Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: SWEKVTGHNS PLYKRQEESG AAASLNVDAA VQQWLQKGTP ASKLILGMPT YGRSFTLASS SDTRVGAPAT GSGTPGPFTK EGGMLAYYEV CSWKGATKQR IQDQKVPYIF RDNQWVGFDD VESFKTKVSY LKQKGLGGAM VWALDLDDFA GFSCNQGRYP LIQTLRQELS LPYLPSGTPE LEVPKPGQPS EPEHGPSPGQ DTFCQGKADG LYPNPRERSS FYSCAAGRLF QQSCPTGLVF SNSCKCCTWN
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chitinase 1 (chitotriosidase); Chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Gene Aliases: 2300002L19Rik; CHI3; CHIT; CHIT1; CHITD
UniProt ID: (Human) Q13231, (Mouse) Q9D7Q1
Entrez Gene ID: (Human) 1118, (Mouse) 71884
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