Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen shares 95% identity with rat.
Specificity of this antibody: CHMP6.
CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Charged multivesicular body protein 6; chromatin modifying protein 6; Chromatin-modifying protein 6; novel SNF7 protein
Gene Aliases: 2400004G01Rik; Chmp6; RGD1565325
UniProt ID: (Mouse) P0C0A3
Entrez Gene ID: (Mouse) 208092, (Rat) 287873
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