Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Muscarinic cholinergic receptor 2 (CHRM2) is an Acetylcholine Receptor has been suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor has also been suggested to mediate smooth muscle contractility. Alzheimer's disease (AD) involves selective loss of M2 subtype receptors in cortical and hippocampal regions of the human brain. Increase in M2 receptor heterozygosity has been associated with depression in women. The M2 receptor has been reported to be expressed in various regions of the brain including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, and in lung and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetylcholine receptor; AChR M2; cholinergic receptor; FLJ43243; M2-mAChR; m2AChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; Muscarinic acetylcholine receptor M2
Gene Aliases: AChR-M2; Chrm-2; Chrm2; M2
UniProt ID: (Mouse) Q9ERZ4
Entrez Gene ID: (Mouse) 243764
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