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CHRNB1 Polyclonal Antibody

CHRNB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CHRNB1 Antibody (11553-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human colon cancer using 11553-1-AP (CHRNB1 antibody) at dilution of 1:50 (under 10x lens).

CHRNB1 Antibody in Immunoprecipitation (IP)

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Product Details

11553-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CHRNB1 Fusion Protein Ag2108 (151-501 aa encoded by BC023553)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: CSIQVTYFP FDWQNCTMVF SSYSYDSSEV SLQTGLGPDG QGHQEIHIHE GTFIENGQWE IIHKPSRLIQ PPGDPRGGRE GQRQEVIFYL IIRRKPLFYL VNVIAPCILI TLLAIFVFYL PPDAGEKMGL SIFALLTLTV FLLLLADKVP ETSLSVPIII KYLMFTMVLV TFSVILSVVV LNLHHRSPHT HQMPLWVRQI FIHKLPLYLR LKRPKPERDL MPEPPHCSSP GSGWGRGTDE YFIRKPPSDF LFPKPNRFQP ELSAPDLRRF IDGPNRAVAL LPELREVVSS ISYIARQLQE QEDHDALKED WQFVAMVVDR LFLWTFIIFT SVGTLVIFLD ATYHLPPPDP FP (151-501 aa encoded by BC023553)

Target Information

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

MiR-142a-3p: A novel ACh receptor transcriptional regulator in association with peripheral nerve injury.

Molecular therapy. Nucleic acids

Qi Z,Wang S,Xuan A,Gu X,Deng J,Huang C,Zhang L,Yin X

Tue Dec 13 00:00:00 EST 2022

Association of a newly identified lncRNA LNC_000280 with the formation of acetylcholine receptor clusters in vitro.

Biochemical and biophysical research communications

Deng J,Wang S,Meng S,Qi Z,Gu X,Huang C,Yin X

Sat Jun 25 00:00:00 EDT 2022

A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.

Aging

Wu X,Sheng H,Wang L,Xia P,Wang Y,Yu L,Lv W,Hu J

Fri Mar 26 00:00:00 EDT 2021

A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.

Translational psychiatry

Guo Y,Zhu X,Zeng M,Qi L,Tang X,Wang D,Zhang M,Xie Y,Li H,Yang X,Chen D

Thu May 27 00:00:00 EDT 2021

Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.

Aging

Wang D,Zhang H,Zeng M,Tang X,Zhu X,Guo Y,Qi L,Xie Y,Zhang M,Chen D

Fri Mar 26 00:00:00 EDT 2021

Plasticity of the murine spleen T-cell cholinergic receptors and their role in in vitro differentiation of naïve CD4 T cells toward the Th1, Th2 and Th17 lineages.

Genes and immunity

Qian J,Galitovskiy V,Chernyavsky AI,Marchenko S,Grando SA

Fri Apr 01 00:00:00 EDT 2011

Plasticity of the murine spleen T-cell cholinergic receptors and their role in in vitro differentiation of naïve CD4 T cells toward the Th1, Th2 and Th17 lineages.

Genes and immunity

Qian J,Galitovskiy V,Chernyavsky AI,Marchenko S,Grando SA

Fri Apr 01 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: acetylcholine receptor; Acetylcholine receptor beta; Acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); AChR beta; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 1; cholinergic receptor, nicotinic beta 1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); Chrnb 1; nAChRB1

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Gene Aliases: Achr-2; ACHRB; Acrb; CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; RNACRB1; SCCMS

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UniProt ID: (Human) P11230, (Rat) P25109, (Mouse) P09690

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Entrez Gene ID: (Human) 1140, (Rat) 24261, (Mouse) 11443

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Function(s)

acetylcholine-activated cation-selective channel activity channel activity ligand-gated ion channel activity acetylcholine receptor activity acetylcholine binding ion channel activity extracellular ligand-gated ion channel activity protein binding ligand-gated ion channel

Process(es)

postsynaptic membrane organization skeletal muscle contraction cation transport muscle contraction signal transduction synaptic transmission, cholinergic neuromuscular synaptic transmission behavioral response to nicotine regulation of membrane potential muscle fiber development neurological system process cation transmembrane transport ion transmembrane transport transmembrane transport transport ion transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CHRNB1 Polyclonal Antibody

CHRNB1 Antibody (11553-1-AP) in IHC (P)

Product Details

11553-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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