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Immunogen sequence: LAYKRFYVKD HRNKAMINLH IQKDNPKIVH AFDMEDLGDK AVYCRCWRSK KFPFCDGAHT KHNEETGDNV GPLIIKKKET; Positive Samples: HeLa, Mouse liver, Mouse heart, Mouse skeletal muscle, Rat brain; Cellular Location: Mitochondrion outer membrane, Single-pass type III membrane protein
This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2.
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Protein Aliases: CDGSH iron sulfur domain-containing protein 1; CDGSH iron-sulfur domain-containing protein 1; Cysteine transaminase CISD1; MGC14684; MitoNEET; zinc finger, CDGSH-type domain 1
Gene Aliases: AU043990; AW743335; Cisd1; D10Ertd214e; MitoNEET; RGD1309529; Zcd1
UniProt ID: (Mouse) Q91WS0, (Rat) B0K020
Entrez Gene ID: (Mouse) 52637, (Rat) 294362
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