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Proteintech
Flotillin 1 Monoclonal Antibody (1D6C6), CoraLite® Plus 488
FIGURE: 1 / 1
Flotillin 1 Antibody (CL488-67968) in Flow
1X10^6 Raji cells were intracellularly stained with 0.8 µg CoraLite® Plus 488 Anti-Human Flotillin 1 (CL488-67968, Clone:1D6C6) (red), or 0.8 µg CoraLite® Plus 488 Mouse IgG2b Isotype Control (MPC-11) (CL488-65128, Clone: MPC-11) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-67968
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1D6C6
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MLAAACQMFL GKTEAEIAHI ALETLEGHQR AIMAHMTVEE IYKDRQKFSE QVFKVASSDL VNMGISVVSY TLKDIHDDQD YLHSLGKART AQVQKDARIG EAEAKRDAGI REAKAKQEKV SAQYLSEIEM AKAQRDYELK KAAYDIEVNT RRAQADLAYQ LQVAKTKQQI EEQRVQVQVV ERAQQVAVQE QEIARREKEL EARVRKPAEA ERYKLERLAE AEKSQLIMQA EAEAASVRMR GEAEAFAIGA RARAEAEQMA KKAEAFQLYQ EAAQLDMLLE KLPQVAEEIS GPLTSANKIT LVSSGSGTMG AAKVTGEVLD ILTRLPESVE RLTGVSISQV NHKPLRTA
Target Information
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DADB-118P11.2; Flotillin-1; integral membrane component of caveolae; OTTHUMP00000164855; REG-2; Reggie-2
Gene Aliases: FLOT1; Rareg; Reg2; reggie-2
UniProt ID: (Human) O75955, (Pig) Q767L6, (Mouse) O08917, (Rat) Q9Z1E1
Entrez Gene ID: (Human) 10211, (Pig) 100151746, (Rabbit) 100358951, (Mouse) 14251, (Rat) 64665
membrane raft assembly
positive regulation of cytokine production
positive regulation of protein phosphorylation
regulation of receptor internalization
endocytosis
axonogenesis
axon guidance
extracellular matrix disassembly
positive regulation of protein binding
positive regulation of interferon-beta production
dsRNA transport
positive regulation of heterotypic cell-cell adhesion
positive regulation of toll-like receptor 3 signaling pathway
response to endoplasmic reticulum stress
regulation of Rho protein signal transduction
plasma membrane raft assembly
positive regulation of endocytosis
positive regulation of skeletal muscle tissue development
protein homooligomerization
positive regulation of cell adhesion molecule production
protein kinase C signaling
cellular response to exogenous dsRNA
protein localization to plasma membrane
establishment of protein localization to plasma membrane
positive regulation of myoblast fusion
positive regulation of cell junction assembly
protein localization to membrane raft
positive regulation of cell-cell adhesion mediated by cadherin
positive regulation of synaptic transmission, dopaminergic
regulation of toll-like receptor 4 signaling pathway
protein stabilization
positive regulation of NF-kappaB transcription factor activity
regulation of neurotransmitter uptake
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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