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Product Details
CL594-68069
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1C10E3
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTILYKLKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGG QDKIRPLWRH YFQNTQGLIF VVDSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKLGLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K
Target Information
ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor 1
Gene Aliases: ARF1
UniProt ID: (Human) P84077, (Mouse) P84078, (Rat) P84079
Entrez Gene ID: (Human) 375, (Rabbit) 100354334, (Mouse) 11840, (Rat) 64310
regulation of receptor internalization
phosphatidylinositol biosynthetic process
cellular copper ion homeostasis
post-Golgi vesicle-mediated transport
actin filament organization
small GTPase mediated signal transduction
protein transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
regulation of Arp2/3 complex-mediated actin nucleation
very-low-density lipoprotein particle assembly
positive regulation of catalytic activity
positive regulation of endocytosis
positive regulation of calcium ion-dependent exocytosis
regulation of defense response to virus by virus
positive regulation of protein secretion
Golgi to transport vesicle transport
long term synaptic depression
positive regulation of dendritic spine development
synaptic vesicle budding
dendritic spine organization
lysosomal membrane organization
positive regulation of sodium ion transmembrane transport
positive regulation of late endosome to lysosome transport
positive regulation of ER to Golgi vesicle-mediated transport
regulation of phospholipid metabolic process
transport
vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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