Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: ACRHGDRCSR LHNKPTFSQT IALLNIYRNP QNSSQSADGL RCAVSDVEMQ EHYDEFFEEV FTEMEEKYGE VEEMNVCDNL GDHLVGNVYV KFRREEDAEK AVIDLNNRWF NGQPIHAELS PVTDFREACC RQYEMGECTR GGFCNFMHLK PISRELRREL YGRRRKKHRS RSRSRERRSR SRDRGRGGGG GGGGGGGGRE RDRRRSRDRE RSGRF
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: Splicing factor U2AF 35 kDa subunit; splicing factor U2AF 35kDa subunit; U2 auxiliary factor 35 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF),35 kDa; U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit; U2 small nuclear RNA auxiliary factor 1; U2 small nuclear RNA auxillary factor 1; U2 snRNP auxiliary factor small subunit; U2(RNU2) small nuclear RNA auxiliary factor binding protein
Gene Aliases: 2010107D16Rik; 35kDa; FP793; RN; RNU2AF1; U2AF1; U2AF35; U2AFBP
UniProt ID: (Human) Q01081, (Mouse) Q9D883
Entrez Gene ID: (Human) 7307, (Mouse) 108121, (Rat) 687575
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