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CLCN5 Antibody (OSC00239W-100UL) in IHC (P)
IHC-P on paraffin sections of rat cerebellum. The section appears largely negative. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 100 mL of 37C PBS and then fixed with 300 mL 4% FA (37C) before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP pol... View More
Product Details
OSC00239W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mouse CLCN5 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and human.
Specificity of this antibody: CLCN5.
Target Information
Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: chloride channel 5; Chloride channel protein 5; chloride channel, voltage-sensitive 5; Chloride transporter ClC-5; ClC-5; H(+)/Cl(-) exchange transporter 5; hClC-K2; voltage-gated chloride ion channel CLCN5
Gene Aliases: 5430408K11Rik; ClC-5; CLC5; CLCK2; CLCN5; D930009B12Rik; DENTS; DXImx42e; hCIC-K2; NPHL1; NPHL2; Sfc13; T25545; XLRH; XRN
UniProt ID: (Human) P51795, (Rat) P51796, (Mouse) Q9WVD4
Entrez Gene ID: (Human) 1184, (Rat) 25749, (Mouse) 12728
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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