Proteintech

COLEC11 Polyclonal Antibody

COLEC11 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

COLEC11 Antibody (15269-1-AP) in ICC/IF

IF result (confocal image) of CL-K1 in ATCD5 cell show Golgi localization from Prof. Philip L. Beales.

COLEC11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

COLEC11 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

15269-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 2 publications 2 publications

Flow Cytometry (Flow)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

COLEC11 Fusion Protein Ag7374 (18-271 aa encoded by BC000078)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SLLPSGHPQ PAGDDACSVQ ILVPGLKGDA GEKGDKGAPG RPGRVGPTGE KGDMGDKGQK GSVGRHGKIG PIGSKGEKGD SGDIGPPGPN GEPGLPCECS QLRKAIGEMD NQVSQLTSEL KFIKNAVAGV RETESKIYLL VKEEKRYADA QLSCQGRGGT LSMPKDEAAN GLMAAYLAQA GLARVFIGIN DLEKEGAFVY SDHSPMRTFN KWRSGEPNNA YDEEDCVEMV ASGGWNDVAC HTTMYFMCEF DKENM (18-271 aa encoded by B C000078)

Target Information

This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Collectin11 and Complement Activation in IgA Nephropathy.

Clinical journal of the American Society of Nephrology : CJASN

Wei M,Guo WY,Xu BY,Shi SF,Liu LJ,Zhou XJ,Lv JC,Zhu L,Zhang H

Wed Dec 01 00:00:00 EST 2021

Collectin11 and Complement Activation in IgA Nephropathy.

Clinical journal of the American Society of Nephrology : CJASN

Wei M,Guo WY,Xu BY,Shi SF,Liu LJ,Zhou XJ,Lv JC,Zhu L,Zhang H

Wed Dec 01 00:00:00 EST 2021

iTRAQ plasma proteomics analysis for candidate biomarkers of type 2 incipient diabetic nephropathy.

Clinical proteomics

Lu H,Deng S,Zheng M,Hu K

Sat Apr 09 00:00:00 EDT 2022

Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1).

Frontiers in immunology

Bayarri-Olmos R,Kirketerp-Moller N,Pérez-Alós L,Skjodt K,Skjoedt MO,Garred P

Mon Oct 21 00:00:00 EDT 2019

Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1).

Frontiers in immunology

Bayarri-Olmos R,Kirketerp-Moller N,Pérez-Alós L,Skjodt K,Skjoedt MO,Garred P

Mon Oct 21 00:00:00 EDT 2019

Heterocomplex formation between MBL/ficolin/CL-11-associated serine protease-1 and -3 and MBL/ficolin/CL-11-associated protein-1.

Journal of immunology (Baltimore, Md. : 1950)

Rosbjerg A,Munthe-Fog L,Garred P,Skjoedt MO

Thu May 01 00:00:00 EDT 2014

Heterocomplex formation between MBL/ficolin/CL-11-associated serine protease-1 and -3 and MBL/ficolin/CL-11-associated protein-1.

Journal of immunology (Baltimore, Md. : 1950)

Rosbjerg A,Munthe-Fog L,Garred P,Skjoedt MO

Thu May 01 00:00:00 EDT 2014

Collectin-11/MASP complex formation triggers activation of the lectin complement pathway--the fifth lectin pathway initiation complex.

Journal of innate immunity

Ma YJ,Skjoedt MO,Garred P

Mon Nov 04 00:00:00 EST 2013

Collectin-11/MASP complex formation triggers activation of the lectin complement pathway--the fifth lectin pathway initiation complex.

Journal of innate immunity

Ma YJ,Skjoedt MO,Garred P

Mon Nov 04 00:00:00 EST 2013

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome.

Nature genetics

Rooryck C,Diaz-Font A,Osborn DP,Chabchoub E,Hernandez-Hernandez V,Shamseldin H,Kenny J,Waters A,Jenkins D,Kaissi AA,Leal GF,Dallapiccola B,Carnevale F,Bitner-Glindzicz M,Lees M,Hennekam R,Stanier P,Burns AJ,Peeters H,Alkuraya FS,Beales PL

Tue Mar 01 00:00:00 EST 2011

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome.

Nature genetics

Tue Mar 01 00:00:00 EST 2011

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome.

Nature genetics

Tue Mar 01 00:00:00 EST 2011

Bioinformatics

Protein Aliases: CL-K1; Collectin 11; Collectin K1; Collectin kidney protein 1; collectin sub-family member 11; Collectin-11; Collectin11

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Gene Aliases: 1010001H16Rik; 3MC2; CL-K1-I; CL-K1-II; CL-K1-IIa; CL-K1-IIb; CLK1; COLEC11; UNQ596/PRO1182

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UniProt ID: (Human) Q9BWP8, (Mouse) Q3SXB8

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Entrez Gene ID: (Human) 78989, (Mouse) 71693, (Rat) 366588

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Function(s)

serine-type endopeptidase activity mannose binding carbohydrate binding surfactant

Process(es)

proteolysis receptor-mediated endocytosis complement activation multicellular organism development developmental process biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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COLEC11 Polyclonal Antibody

COLEC11 Antibody (15269-1-AP) in ICC/IF

Product Details

15269-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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