Proteintech

COXIV Polyclonal Antibody

COXIV Antibody in Immunocytochemistry (ICC/IF)

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COXIV Antibody (11242-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using COXIV rabbit pAb (Product # 11242-1-AP) at dilution of 1:100 and alpha Tubulin Mouse mAb (66031-1-Ig) at dilution of 1:200, further stained with CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) for (Product # 11242-1-AP), and CoraLite594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) for 66031-1-Ig.

COXIV Antibody in Immunohistochemistry (Paraffin) (IHC (P))

COXIV Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11242-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:50,000

View 302 publications 302 publications

Immunohistochemistry (IHC)

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000

Immunocytochemistry (ICC/IF)

1:50-1:500

View 29 publications 29 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

ChIP assay (ChIP)

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 3 publications 3 publications

Not applicable (N/A)

View 6 publications 6 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

COXIV Fusion Protein Ag1640 (1-169 aa encoded by BC021236)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody was generated against full length COX4I1 protein and cross reacts with COX4I2.

Immunogen sequence: MLATRVFSL VGKRAISTSV CVRAHESVVK SEDFSLPAYM DRRDHPLPEV AHVKHLSASQ KALKEKEKAS WSSLSMDEKV ELYRIKFKES FAEMNRGSNE WKTVVGGAMF FIGFTALVIM WQKHYVYGPL PQSFDKEWVA KQTKRMLDMK VNPIQGLASK WDYEKNEWKK (1-169 aa encoded by BC021236)

Target Information

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4 (COX4I1) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Zhang MY,Zhu L,Bao X,Xie TH,Cai J,Zou J,Wang W,Gu S,Li Y,Li HY,Yao Y,Wei TT

Fri Jul 01 00:00:00 EDT 2022

Protective effect of low-dose radiation on doxorubicin-induced brain injury in mice.

Archives of biochemistry and biophysics

Gao Y,Dong J,Chen M,Wang T,Yang Z,He K,Li Y,Wang K,Jiang J,Zhang S

Sun Oct 30 00:00:00 EDT 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 EDT 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 EDT 2022

Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Zhang X,Jia Y,Yuan Z,Wen Y,Zhang Y,Ren J,Ji P,Yao W,Hua Y,Wei Y

Tue Mar 01 00:00:00 EST 2022

B16 Membrane-Coated Vesicles for Combined Photodynamic Therapy and Immunotherapy Shift Immune Microenvironment of Melanoma.

International journal of nanomedicine

Wang Y,Zhao Z,Liu C,Hao M,Kong C,Zhao X,Gao Y,Zhang Y,Cui W,Zhang C,Jiang J

Mon Apr 04 00:00:00 EDT 2022

HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region.

Ecotoxicology and environmental safety

Bao S,Zhang C,Luo S,Jiang L,Li Q,Kong Y,Cao J

Sat Oct 01 00:00:00 EDT 2022

Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.

Journal of molecular histology

Li J,Bu Y,Li B,Zhang H,Guo J,Hu J,Zhang Y

Mon Aug 01 00:00:00 EDT 2022

Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.

Science advances

Guo Q,Xu Z,Zhou D,Fu T,Wang W,Sun W,Xiao L,Liu L,Ding C,Yin Y,Zhou Z,Sun Z,Zhu Y,Zhou W,Jia Y,Xue J,Chen Y,Chen XW,Piao HL,Lu B,Gan Z

Fri Jul 29 00:00:00 EDT 2022

Acetaldehyde Induces Cytotoxicity via Triggering Mitochondrial Dysfunction and Overactive Mitophagy.

Molecular neurobiology

Yan T,Zhao Y,Jiang Z,Chen J

Wed Jun 01 00:00:00 EDT 2022

Pentatricopeptide Protein PTCD2 Regulates COIII Translation in Mitochondria of the HeLa Cell Line.

International journal of molecular sciences

Baleva MV,Chicherin I,Piunova U,Zgoda V,Patrushev MV,Levitskii S,Kamenski P

Thu Nov 17 00:00:00 EST 2022

HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.

Biochemical and biophysical research communications

Liu D,Sun H,Li K,Zhao Z,Liu Z,Zhang G,Ge Y,Zhang J,Wang D,Leng Y

Sat Aug 27 00:00:00 EDT 2022

Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.

Frontiers in oncology

Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P

Sat May 07 00:00:00 EDT 2022

CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.

Proceedings of the National Academy of Sciences of the United States of America

Yu J,Liufu T,Zheng Y,Xu J,Meng L,Zhang W,Yuan Y,Hong D,Charlet-Berguerand N,Wang Z,Deng J

Tue Oct 11 00:00:00 EDT 2022

Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.

Inflammation

Zeng L,He J,Liu C,Zhang F,Zhang Z,Chen H,Wang Q,Ding X,Luo H

Fri Apr 01 00:00:00 EDT 2022

PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.

Cell death & disease

Li J,Lai M,Zhang X,Li Z,Yang D,Zhao M,Wang D,Sun Z,Ehsan S,Li W,Gao H,Zhao D,Yang L

Fri Feb 18 00:00:00 EST 2022

CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis.

Diabetes

Ding M,Ma YJ,Du RQ,Zhou WY,Dou X,Yang QQ,Tang Y,Qian SW,Liu Y,Pan DN,Tang QQ,Liu Y

Thu Sep 01 00:00:00 EDT 2022

Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner.

The Journal of nutritional biochemistry

Tanaka E,Mitani T,Nakashima M,Yonemoto E,Fujii H,Ashida H

Tue Feb 01 00:00:00 EST 2022

PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.

Diabetes

Li C,Li L,Yang M,Yang J,Zhao C,Han Y,Zhao H,Jiang N,Wei L,Xiao Y,Liu Y,Xiong X,Xi Y,Luo S,Deng F,Chen W,Yuan S,Zhu X,Xiao L,Sun L

Sun May 01 00:00:00 EDT 2022

1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.

Toxicology and applied pharmacology

Chang X,Wang J,Bian J,Liu Z,Guo M,Li Z,Wu Y,Zhai X,Zuo D

Thu Sep 01 00:00:00 EDT 2022

An elemental diet protects mouse salivary glands from 5-fluorouracil-induced atrophy.

Oncology letters

Harada K,Ferdous T,Fujiwara R,Watanabe K,Mizukami Y,Mishima K

Wed Jun 01 00:00:00 EDT 2022

Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.

Nature communications

Xu Z,Fu T,Guo Q,Zhou D,Sun W,Zhou Z,Chen X,Zhang J,Liu L,Xiao L,Yin Y,Jia Y,Pang E,Chen Y,Pan X,Fang L,Zhu MS,Fei W,Lu B,Gan Z

Wed Feb 16 00:00:00 EST 2022

Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H₂O₂-induced human granulosa cell line KGN.

Journal of ethnopharmacology

Liu J,Shi D,Ma Q,Zhao P

Thu Sep 15 00:00:00 EDT 2022

Frontiers in molecular neuroscience

Guo J,Zhang L,Bu Y,Li W,Hu J,Li J

Fri Nov 18 00:00:00 EST 2022

The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.

The Journal of biological chemistry

Sun S,Hou H,Ma G,Ma Q,Li N,Zhang L,Dong C,Cao M,Tam KY,Ying Z,Wang H

Thu Dec 01 00:00:00 EST 2022

Brown adipose tissue involution associated with progressive restriction in progenitor competence.

Cell reports

Huang Z,Zhang Z,Moazzami Z,Heck R,Hu P,Nanda H,Ren K,Sun Z,Bartolomucci A,Gao Y,Chung D,Zhu W,Shen S,Ruan HB

Tue Apr 12 00:00:00 EDT 2022

Glyphosate-induced mitochondrial reactive oxygen species overproduction activates parkin-dependent mitophagy to inhibit testosterone synthesis in mouse leydig cells.

Environmental pollution (Barking, Essex : 1987)

Lu L,Liu JB,Wang JQ,Lian CY,Wang ZY,Wang L

Thu Dec 01 00:00:00 EST 2022

ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.

Human molecular genetics

Lin BC,Phung TH,Higgins NR,Greenslade JE,Prado MA,Finley D,Karbowski M,Polster BM,Monteiro MJ

Thu Jun 17 00:00:00 EDT 2021

Raman Spectroscopic Assessment of Myocardial Viability in Langendorff-Perfused Ischemic Rat Hearts.

Acta histochemica et cytochemica

Ikemoto K,Hashimoto K,Harada Y,Kumamoto Y,Hayakawa M,Mochizuki K,Matsuo K,Yashiro K,Yaku H,Takamatsu T,Tanaka H

Wed Apr 28 00:00:00 EDT 2021

Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.

Theranostics

Luo Q,Xian P,Wang T,Wu S,Sun T,Wang W,Wang B,Yang H,Yang Y,Wang H,Liu W,Long Q

Fri Jul 30 00:00:00 EDT 2021

Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.

Oxidative medicine and cellular longevity

Zhao R,Wang B,Wang D,Wu B,Ji P,Tan D

Thu May 20 00:00:00 EDT 2021

Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.

Autophagy

Huang T,Xu T,Wang Y,Zhou Y,Yu D,Wang Z,He L,Chen Z,Zhang Y,Davidson D,Dai Y,Hang C,Liu X,Yan C

Mon Nov 01 00:00:00 EDT 2021

PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.

Frontiers in cell and developmental biology

Jiang XJ,Wu YQ,Ma R,Chang YM,Li LL,Zhu JH,Liu GP,Li G

Sat Jan 22 00:00:00 EST 2022

Remote Ischemic Postconditioning Inhibits Hippocampal Neuronal Apoptosis and Mitophagy After Cardiopulmonary Resuscitation in Rats.

Shock (Augusta, Ga.)

Xie B,Gao X,Huang Y,Zhang Y,Zhu S

Fri Jan 01 00:00:00 EST 2021

Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.

Journal of hazardous materials

Xiaoli F,Yaqing Z,Ruhui L,Xuan L,Aijie C,Yanli Z,Chen H,Lili C,Longquan S

Sun Aug 15 00:00:00 EDT 2021

VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.

Molecular biology of the cell

Du Y,Wang J,Xiong J,Fang N,Ji WK

Sun Aug 01 00:00:00 EDT 2021

miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.

Oxidative medicine and cellular longevity

Bao Y,Qiao Y,Yu H,Zhang Z,Yang H,Xin X,Chen Y,Guo Y,Wu N,Jia D

Tue Jan 11 00:00:00 EST 2022

Protective autophagy attenuates soft substrate-induced apoptosis through ROS/JNK signaling pathway in breast cancer cells.

Free radical biology & medicine

Chen Y,Li P,Peng Y,Xie X,Zhang Y,Jiang Y,Li T,Qin X,Li S,Yang H,Wu C,Zheng C,Zhu J,You F,Liu Y

Fri Aug 20 00:00:00 EDT 2021

The positive regulation loop between NRF1 and NONO-TFE3 fusion promotes phase separation and aggregation of NONO-TFE3 in NONO-TFE3 tRCC.

International journal of biological macromolecules

Wang B,Gan W,Han X,Liu N,Ma T,Li D

Thu Apr 15 00:00:00 EDT 2021

3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures.

Journal of nanobiotechnology

Zhang W,Zhao W,Li Q,Zhao D,Qu J,Yuan Z,Cheng Z,Zhu X,Zhuang X,Zhang Z

Sat Sep 04 00:00:00 EDT 2021

Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice.

Biological trace element research

Lai H,Nie T,Zhang Y,Chen Y,Tao J,Lin T,Ge T,Li F,Li H

Fri Jan 01 00:00:00 EST 2021

trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.

Scientific reports

Hirata Y,Takahashi M,Yamada Y,Matsui R,Inoue A,Ashida R,Noguchi T,Matsuzawa A

Fri May 14 00:00:00 EDT 2021

UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.

Molecular oncology

Liu F,Pan R,Ding H,Gu L,Yang Y,Li C,Xu Y,Hu R,Chen H,Zhang X,Nie Y

Wed Dec 01 00:00:00 EST 2021

MiR-133a-3p relieves the oxidative stress induced trophoblast cell apoptosis through the BACH1/Nrf2/HO-1 signaling pathway.

Physiological research

Guo H,Wang Y,Jia W,Liu L

Wed Mar 17 00:00:00 EDT 2021

Mitochondria transplantation protects traumatic brain injury via promoting neuronal survival and astrocytic BDNF.

Translational research : the journal of laboratory and clinical medicine

Zhao J,Qu D,Xi Z,Huan Y,Zhang K,Yu C,Yang D,Kang J,Lin W,Wu S,Wang Y

Wed Sep 01 00:00:00 EDT 2021

Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence.

Frontiers in immunology

Li Q,Deng Y,Liu L,Zhang C,Cai Y,Zhang T,Han M,Xu G

Thu Mar 03 00:00:00 EST 2022

S100B/RAGE/Ceramide signaling pathway is involved in sepsis-associated encephalopathy.

Life sciences

Zhang L,Jiang Y,Deng S,Mo Y,Huang Y,Li W,Ge C,Ren X,Zhang H,Zhang X,Peng Q,Liu Z,Huang L,Zhou F,Ai Y

Thu Jul 15 00:00:00 EDT 2021

PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.

Autophagy

Wang B,Yin X,Gan W,Pan F,Li S,Xiang Z,Han X,Li D

Wed Sep 01 00:00:00 EDT 2021

Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.

Oxidative medicine and cellular longevity

Lv D,Luo M,Cheng Z,Wang R,Yang X,Guo Y,Huang L,Li X,Huang B,Shen J,Luo S,Yan J

Mon Feb 07 00:00:00 EST 2022

Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.

Oxidative medicine and cellular longevity

Yang DQ,Zuo QN,Wang T,Xu D,Lian L,Gao LJ,Wan C,Chen L,Wen FQ,Shen YC

Tue Dec 28 00:00:00 EST 2021

Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.

International journal of biological sciences

Liu Y,Shi C,He Z,Zhu F,Wang M,He R,Zhao C,Shi X,Zhou M,Pan S,Gao Y,Li X,Qin R

Mon Jan 03 00:00:00 EST 2022

Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.

Human & experimental toxicology

Chen Y,Tian Y,Jin G,Cui Z,Guo W,Zhang X,Liu X

Wed Dec 01 00:00:00 EST 2021

Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.

Frontiers in physiology

Xu L,Xu C,Liu X,Li X,Li T,Yu X,Xue M,Yang J,Kosmas CE,Moris D,Sanchis-Gomar F,Yoshida N,Berger NA,Aronow WS,Sun B,Chen L

Wed Nov 17 00:00:00 EST 2021

Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.

Frontiers in physiology

Xu L,Xu C,Liu X,Li X,Li T,Yu X,Xue M,Yang J,Kosmas CE,Moris D,Sanchis-Gomar F,Yoshida N,Berger NA,Aronow WS,Sun B,Chen L

Wed Nov 17 00:00:00 EST 2021

Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.

Oxidative medicine and cellular longevity

Li Y,Yuan Y,Li Y,Han D,Liu T,Yang N,Mi X,Hong J,Liu K,Song Y,He J,Zhou Y,Han Y,Shi C,Yu S,Zou P,Guo X,Li Z

Tue Jan 04 00:00:00 EST 2022

Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.

Oxidative medicine and cellular longevity

Li Y,Yuan Y,Li Y,Han D,Liu T,Yang N,Mi X,Hong J,Liu K,Song Y,He J,Zhou Y,Han Y,Shi C,Yu S,Zou P,Guo X,Li Z

Tue Jan 04 00:00:00 EST 2022

Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effect.

Nature metabolism

Wiese EK,Hitosugi S,Loa ST,Sreedhar A,Andres-Beck LG,Kurmi K,Pang YP,Karnitz LM,Gonsalves WI,Hitosugi T

Thu Jul 01 00:00:00 EDT 2021

Transcription-Based Multidimensional Regulation of Fatty Acid Metabolism by HIF1α in Renal Tubules.

Frontiers in cell and developmental biology

Li W,Duan A,Xing Y,Xu L,Yang J

Tue Jul 20 00:00:00 EDT 2021

Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation.

Frontiers in cell and developmental biology

Wang Y,Jiang T,Xu J,Gu Y,Zhou Y,Lin Y,Wu Y,Li W,Wang C,Shen B,Mo X,Wang X,Zhou B,Ding C,Hu Z

Thu May 13 00:00:00 EDT 2021

A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.

Toxicology

Mei J,Dlamini MB,Gao Z,Jiang L,Li Q,Geng C,Shi X,Liu Y,Kong Y,Cao J

Fri Oct 01 00:00:00 EDT 2021

SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy.

Cell death & disease

Yang X,Xue P,Yuan M,Xu X,Wang C,Li W,Machens HG,Chen Z

Tue Aug 24 00:00:00 EDT 2021

USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.

Biochemical and biophysical research communications

Wang N,Li J,Xin Q,Xu N

Fri Dec 03 00:00:00 EST 2021

Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.

Developmental cell

Lei Y,Zhang X,Xu Q,Liu S,Li C,Jiang H,Lin H,Kong E,Liu J,Qi S,Li H,Xu W,Lu K

Mon Aug 23 00:00:00 EDT 2021

Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.

Frontiers in cardiovascular medicine

Xu R,Kang L,Wei S,Yang C,Fu Y,Ding Z,Zou Y

Tue Oct 12 00:00:00 EDT 2021

High-Fat Diet-Induced Mitochondrial Dysfunction Promotes Genioglossus Injury - A Potential Mechanism for Obstructive Sleep Apnea with Obesity.

Nature and science of sleep

Chen Q,Han X,Chen M,Zhao B,Sun B,Sun L,Zhang W,Yu L,Liu Y

Fri Apr 29 00:00:00 EDT 2022

p53 induces ARTS to promote mitochondrial apoptosis.

Cell death & disease

Hao Q,Chen J,Liao J,Huang Y,Gan Y,Larisch S,Zeng SX,Lu H,Zhou X

Wed Feb 24 00:00:00 EST 2021

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.

Emerging microbes & infections

Moustaqil M,Ollivier E,Chiu HP,Van Tol S,Rudolffi-Soto P,Stevens C,Bhumkar A,Hunter DJB,Freiberg AN,Jacques D,Lee B,Sierecki E,Gambin Y

Wed Dec 01 00:00:00 EST 2021

The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.

Cell reports

Li S,Kuang M,Chen L,Li Y,Liu S,Du H,Cao L,You F

Tue Jan 19 00:00:00 EST 2021

Bioactive compound from the Tibetan turnip (Brassica rapa L.) elicited anti-hypoxia effects in OGD/R-injured HT22 cells by activating the PI3K/AKT pathway.

Food & function

Hua H,Zhu H,Liu C,Zhang W,Li J,Hu B,Guo Y,Cheng Y,Pi F,Xie Y,Yao W,Qian H

Wed Apr 07 00:00:00 EDT 2021

Neuroprotection against cerebral ischemia/reperfusion by dietary phytochemical extracts from Tibetan turnip (Brassica rapa L.).

Journal of ethnopharmacology

Hua H,Zhang W,Li J,Li J,Liu C,Guo Y,Cheng Y,Pi F,Xie Y,Yao W,Gao Y,Qian H

Sat Jan 30 00:00:00 EST 2021

Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.

Journal of cellular physiology

Wu L,Wang Q,Guo F,Ma X,Wang J,Zhao Y,Yan Y,Qin G

Mon Feb 01 00:00:00 EST 2021

A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca²⁺ influx through mitochondrial calcium uniporter.

Toxicology and applied pharmacology

Xue P,Chen Q,Ren X,Liu D,Yang X

Wed Dec 15 00:00:00 EST 2021

Methionine synthase supports tumour tetrahydrofolate pools.

Nature metabolism

Ghergurovich JM,Xu X,Wang JZ,Yang L,Ryseck RP,Wang L,Rabinowitz JD

Mon Nov 01 00:00:00 EDT 2021

TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy.

Frontiers in cell and developmental biology

Zhang MY,Zhu L,Zheng X,Xie TH,Wang W,Zou J,Li Y,Li HY,Cai J,Gu S,Yao Y,Wei TT

Tue Feb 01 00:00:00 EST 2022

Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.

Toxicology

Arzuk E,Karakuş F,Orhan H

Fri Jan 15 00:00:00 EST 2021

AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.

PLoS genetics

Xiao L,Liu J,Sun Z,Yin Y,Mao Y,Xu D,Liu L,Xu Z,Guo Q,Ding C,Sun W,Yang L,Zhou Z,Zhou D,Fu T,Zhou W,Zhu Y,Chen XW,Li JZ,Chen S,Xie X,Gan Z

Mon Mar 01 00:00:00 EST 2021

EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation.

Cancer cell international

Chang M,Shang M,Yuan F,Guo W,Wang C

Tue Oct 12 00:00:00 EDT 2021

Empagliflozin alleviates ethanol-induced cardiomyocyte injury through inhibition of mitochondrial apoptosis via a SIRT1/PTEN/Akt pathway.

Clinical and experimental pharmacology & physiology

Tian G,Yu Y,Deng H,Yang L,Shi X,Yu B

Tue Jun 01 00:00:00 EDT 2021

Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca²⁺ homeostasis.

Cell biology and toxicology

Zhong Y,Jin C,Han J,Zhu J,Liu Q,Sun D,Xia X,Peng X

Fri Oct 01 00:00:00 EDT 2021

OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.

EMBO reports

Wu Z,Zuo M,Zeng L,Cui K,Liu B,Yan C,Chen L,Dong J,Shangguan F,Hu W,He H,Lu B,Song Z

Thu Jan 07 00:00:00 EST 2021

Influence of psychostimulants and opioids on epigenetic modification of class III histone deacetylase (HDAC)-sirtuins in glial cells.

Scientific reports

Sivalingam K,Doke M,Khan MA,Samikkannu T

Fri Oct 29 00:00:00 EDT 2021

Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics.

Autophagy

Nie T,Tao K,Zhu L,Huang L,Hu S,Yang R,Xu P,Mao Z,Yang Q

Fri Oct 01 00:00:00 EDT 2021

Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.

Toxicology research

Wang HX,Zhang R,Li Z,Wang LS,Yu Y,Wang Q,Ding Z,Zhang JP,Zhang MR,Xu LC

Sun Aug 01 00:00:00 EDT 2021

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.

Nature cell biology

Shi M,Huang XY,Ren XY,Wei XY,Ma Y,Lin ZZ,Liu DT,Song L,Zhao TJ,Li G,Yao L,Zhu M,Zhang C,Xie C,Wu Y,Wu HM,Fan LP,Ou J,Zhan YH,Lin SY,Lin SC

Mon Mar 01 00:00:00 EST 2021

Load-matched acute and chronic exercise induce changes in mitochondrial biogenesis and metabolic markers.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

Rodrigues NA,Gobatto CA,Forte LDM,Sousa FAB,Torsoni AS,Fante T,Manchado-Gobatto FB

Fri Oct 01 00:00:00 EDT 2021

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.

iScience

Zou Q,Yang L,Shi R,Qi Y,Zhang X,Qi H

Fri Dec 17 00:00:00 EST 2021

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.

iScience

Zou Q,Yang L,Shi R,Qi Y,Zhang X,Qi H

Fri Dec 17 00:00:00 EST 2021

Kir6.2 is essential to maintain neurite features by modulating PM20D1-reduced mitochondrial ATP generation.

Redox biology

Song N,Fang Y,Zhu H,Liu J,Jiang S,Sun S,Xu R,Ding J,Hu G,Lu M

Mon Nov 01 00:00:00 EDT 2021

miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes.

Life sciences

Tai Y,Pu M,Yuan L,Guo H,Qiao J,Lu H,Wang G,Chen J,Qi X,Tao Z,Ren J

Thu Jul 01 00:00:00 EDT 2021

Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.

Human & experimental toxicology

Dong Z,Bian L,Wang YL,Sun LM

Wed Sep 01 00:00:00 EDT 2021

Exogenous H₂ S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.

Journal of cellular and molecular medicine

Zhang L,Jiang X,Liu N,Li M,Kang J,Chen L,Tang J,Dong S,Lu F,Zhang W

Wed Sep 01 00:00:00 EDT 2021

Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.

Journal of ethnopharmacology

Qin W,Tong X,Liang R,Tang K,Wu X,Jia Y,Tan N

Mon May 10 00:00:00 EDT 2021

Cordycepin Decreases Ischemia/Reperfusion Injury in Diabetic Hearts via Upregulating AMPK/Mfn2-dependent Mitochondrial Fusion.

Frontiers in pharmacology

Yu H,Hong X,Liu L,Wu Y,Xie X,Fang G,Zhi S

Wed Nov 10 00:00:00 EST 2021

Docosahexaenoic acid promotes the formation of autophagosomes in MCF-7 breast cancer cells through oxidative stress-induced growth inhibitor 1 mediated activation of AMPK/mTOR pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Tsai CH,Lii CK,Wang TS,Liu KL,Chen HW,Huang CS,Li CC

Sun Aug 01 00:00:00 EDT 2021

Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.

Frontiers in cell and developmental biology

Mao X,Gu Y,Sui X,Shen L,Han J,Wang H,Xi Q,Zhuang Q,Meng Q,Wu G

Tue Apr 26 00:00:00 EDT 2022

Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.

Neuropharmacology

Wang M,Wan C,He T,Han C,Zhu K,Waddington JL,Zhen X

Wed Sep 15 00:00:00 EDT 2021

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.

Immunity

Lou F,Sun Y,Xu Z,Niu L,Wang Z,Deng S,Liu Z,Zhou H,Bai J,Yin Q,Cai X,Sun L,Wang H,Li Q,Wu Z,Chen X,Gu J,Shi YL,Tao W,Ginhoux F,Wang H

Tue Jul 14 00:00:00 EDT 2020

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.

Immunity

Lou F,Sun Y,Xu Z,Niu L,Wang Z,Deng S,Liu Z,Zhou H,Bai J,Yin Q,Cai X,Sun L,Wang H,Li Q,Wu Z,Chen X,Gu J,Shi YL,Tao W,Ginhoux F,Wang H

Tue Jul 14 00:00:00 EDT 2020

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.

Immunity

Lou F,Sun Y,Xu Z,Niu L,Wang Z,Deng S,Liu Z,Zhou H,Bai J,Yin Q,Cai X,Sun L,Wang H,Li Q,Wu Z,Chen X,Gu J,Shi YL,Tao W,Ginhoux F,Wang H

Tue Jul 14 00:00:00 EDT 2020

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.

Immunity

Lou F,Sun Y,Xu Z,Niu L,Wang Z,Deng S,Liu Z,Zhou H,Bai J,Yin Q,Cai X,Sun L,Wang H,Li Q,Wu Z,Chen X,Gu J,Shi YL,Tao W,Ginhoux F,Wang H

Tue Jul 14 00:00:00 EDT 2020

16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.

Molecules (Basel, Switzerland)

Chen YC,Wang PY,Huang BM,Chen YJ,Lee WC,Chen YC

Sun Aug 30 00:00:00 EDT 2020

Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.

Stem cell research & therapy

Fan C,Feng J,Tang C,Zhang Z,Feng Y,Duan W,Zhai M,Yan Z,Zhu L,Feng L,Zhu H,Luo E

Thu Oct 15 00:00:00 EDT 2020

Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.

Biochemical pharmacology

Liu YC,Wang HL,Huang YZ,Weng YH,Chen RS,Tsai WC,Yeh TH,Lu CS,Chen YL,Lin YW,Chen YJ,Hsu CC,Chiu CH,Chiu CC

Fri May 01 00:00:00 EDT 2020

RGS12 is required for the maintenance of mitochondrial function during skeletal development.

Cell discovery

Yuan G,Yang S,Liu M,Yang S

Wed Nov 17 00:00:00 EST 2021

trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.

Scientific reports

Hirata Y,Inoue A,Suzuki S,Takahashi M,Matsui R,Kono N,Noguchi T,Matsuzawa A

Mon Feb 17 00:00:00 EST 2020

Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.

Life sciences

Wang Y,Zhang X,Chen W,Gao L,Li J,Song T,Chi J,Zhang X,Shi Z,Dong Y,Yin X,Liu Y

Wed Jul 15 00:00:00 EDT 2020

Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis.

Cancer research

Ghergurovich JM,Esposito M,Chen Z,Wang JZ,Bhatt V,Lan T,White E,Kang Y,Guo JY,Rabinowitz JD

Tue Sep 15 00:00:00 EDT 2020

V-ATPase blockade reduces renal gluconeogenesis and improves insulin secretion in type 2 diabetic rats.

Hypertension research : official journal of the Japanese Society of Hypertension

Hirao J,Tojo A,Hatakeyama S,Satonaka H,Ishimitsu T

Thu Oct 01 00:00:00 EDT 2020

Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses.

Life sciences

Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X

Sat Feb 15 00:00:00 EST 2020

1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.

The Journal of pharmacy and pharmacology

Wang L,Xu X,Liu T,Wang J,Shen J,Guo M,Wu Y,Zhai X,Zuo D

Thu Oct 01 00:00:00 EDT 2020

Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission.

Free radical biology & medicine

Zhou L,Yao M,Tian Z,Song Y,Sun Y,Ye J,Li G,Sng KS,Xu L,Cui X,Wang Y

Wed May 20 00:00:00 EDT 2020

Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA₂ phosphorylation in experimental ischemic stroke.

Cellular signalling

Cao C,Zhou J,Wu X,Qian Y,Hong Y,Mu J,Jin L,Zhu C,Li S

Sat Feb 01 00:00:00 EST 2020

FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Li C,Zhou J,Liu Z,Zhou J,Yao W,Tao J,Shen M,Liu H

Sun Mar 01 00:00:00 EST 2020

OPA1 and MICOS Regulate mitochondrial crista dynamics and formation.

Cell death & disease

Hu C,Shu L,Huang X,Yu J,Li L,Gong L,Yang M,Wu Z,Gao Z,Zhao Y,Chen L,Song Z

Sat Oct 31 00:00:00 EDT 2020

HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.

Cell proliferation

Jiang N,Zhao H,Han Y,Li L,Xiong S,Zeng L,Xiao Y,Wei L,Xiong X,Gao P,Yang M,Liu Y,Sun L

Sun Nov 01 00:00:00 EDT 2020

Dependence of PINK1 accumulation on mitochondrial redox system.

Aging cell

Gao F,Zhang Y,Hou X,Tao Z,Ren H,Wang G

Tue Sep 01 00:00:00 EDT 2020

Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice.

Toxicology letters

Zhao Y,Xu G,Li H,Chang M,Guan Y,Li Y,Wu W,Yao S

Fri May 01 00:00:00 EDT 2020

Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.

Carcinogenesis

Zhuang X,Chen Y,Wu Z,Xu Q,Chen M,Shao M,Cao X,Zhou Y,Xie M,Shi Y,Zeng Y,Bu H

Tue Jul 14 00:00:00 EDT 2020

Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.

Brain sciences

Sivalingam K,Samikkannu T

Sat Sep 05 00:00:00 EDT 2020

Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.

Journal of ethnopharmacology

Meng Q,Qi X,Fu Y,Chen Q,Cheng P,Yu X,Sun X,Wu J,Li W,Zhang Q,Li Y,Wang A,Bian H

Mon Feb 10 00:00:00 EST 2020

Silibinin ameliorats H₂O₂-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells.

Acta histochemica

Guo H,Wang Y,Liu D

Tue Dec 01 00:00:00 EST 2020

Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.

Frontiers in neuroscience

Ji Y,Li Y,Zhao Z,Li P,Xie Y

Tue Apr 19 00:00:00 EDT 2022

Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury.

Biochemical pharmacology

Cheng P,Liu H,Li Y,Pi P,Jiang Y,Zang S,Li X,Fu A,Ren X,Xu J,Holmgren A,Lu J

Fri May 01 00:00:00 EDT 2020

Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.

Laboratory investigation; a journal of technical methods and pathology

Kong H,Wang H,Zhuo Z,Li Z,Tian P,Wu J,Liu J,Chen Z,Zhang J,Luo Q

Tue Sep 01 00:00:00 EDT 2020

Magnetic Susceptibility Difference-Induced Nucleus Positioning in Gradient Ultrahigh Magnetic Field.

Biophysical journal

Tao Q,Zhang L,Han X,Chen H,Ji X,Zhang X

Tue Feb 04 00:00:00 EST 2020

Magnetic Susceptibility Difference-Induced Nucleus Positioning in Gradient Ultrahigh Magnetic Field.

Biophysical journal

Tao Q,Zhang L,Han X,Chen H,Ji X,Zhang X

Tue Feb 04 00:00:00 EST 2020

Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission.

Journal of neurochemistry

Zhou LY,Yao M,Tian ZR,Liu SF,Song YJ,Ye J,Li G,Sun YL,Cui XJ,Wang YJ

Tue Sep 01 00:00:00 EDT 2020

Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.

Chemosphere

Wang HW,Zhu SQ,Liu J,Miao CY,Zhang Y,Zhou BH

Wed Jan 01 00:00:00 EST 2020

The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance.

Cell proliferation

Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X

Sun Mar 01 00:00:00 EST 2020

Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.

Cells

Kalpage HA,Wan J,Morse PT,Lee I,Hüttemann M

Thu Aug 06 00:00:00 EDT 2020

Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.

Theranostics

Yang X,Xue P,Chen H,Yuan M,Kang Y,Duscher D,Machens HG,Chen Z

Thu Apr 08 00:00:00 EDT 2021

Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.

Nature metabolism

Li ST,Huang D,Shen S,Cai Y,Xing S,Wu G,Jiang Z,Hao Y,Yuan M,Wang N,Zhu L,Yan R,Yang D,Wang L,Liu Z,Hu X,Zhou R,Qu K,Li A,Duan X,Zhang H,Gao P

Sun Mar 01 00:00:00 EST 2020

Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.

Experimental cell research

Zhang H,Lian Y,Xie N,Cheng X,Chen C,Xu H,Zheng Y

Sat Aug 15 00:00:00 EDT 2020

Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells.

Redox biology

Xu L,Wu T,Lu S,Hao X,Qin J,Wang J,Zhang X,Liu Q,Kong B,Gong Y,Liu Z,Shao C

Tue Sep 01 00:00:00 EDT 2020

Lysophosphatidic Acid Induces Apoptosis of PC12 Cells Through LPA1 Receptor/LPA2 Receptor/MAPK Signaling Pathway.

Frontiers in molecular neuroscience

Zhang J,Li Y,Wang C,Wang Y,Zhang Y,Huang L,Zhang Z

Mon Sep 28 00:00:00 EDT 2020

Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.

Autophagy

Unno R,Kawabata T,Taguchi K,Sugino T,Hamamoto S,Ando R,Okada A,Kohri K,Yoshimori T,Yasui T

Wed Apr 01 00:00:00 EDT 2020

Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.

Cell death & disease

Fan J,Ren D,Wang J,Liu X,Zhang H,Wu M,Yang G

Tue Feb 18 00:00:00 EST 2020

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.

Nature chemical biology

Ghergurovich JM,García-Cañaveras JC,Wang J,Schmidt E,Zhang Z,TeSlaa T,Patel H,Chen L,Britt EC,Piqueras-Nebot M,Gomez-Cabrera MC,Lahoz A,Fan J,Beier UH,Kim H,Rabinowitz JD

Wed Jul 01 00:00:00 EDT 2020

Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.

Toxicology letters

Zhang X,Huang W,Shao Q,Yang Y,Xu Z,Chen J,Zhang X,Ge X

Mon Jun 01 00:00:00 EDT 2020

Berberine protects against diabetic retinopathy by inhibiting cell apoptosis via deactivation of the NF‑κB signaling pathway.

Molecular medicine reports

Zhai J,Li Z,Zhang H,Ma L,Ma Z,Zhang Y,Zou J,Li M,Ma L,Wang X,Li X

Sun Nov 01 00:00:00 EDT 2020

Prenatal High-Salt Diet-Induced Metabolic Disorders via Decreasing Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring.

Molecular nutrition & food research

Liu Y,Yang C,Feng X,Qi L,Guo J,Zhu D,Thai PN,Zhang Y,Zhang P,Sun M,Lv J,Zhang L,Xu Z,Lu X

Wed Jul 01 00:00:00 EDT 2020

Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate.

Cell death and differentiation

Ma K,Zhang Z,Chang R,Cheng H,Mu C,Zhao T,Chen L,Zhang C,Luo Q,Lin J,Zhu Y,Chen Q

Sun Mar 01 00:00:00 EST 2020

Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.

Oxidative medicine and cellular longevity

Feng TY,Li Q,Ren F,Xi HM,Lv DL,Li Y,Hu JH

Fri Sep 03 00:00:00 EDT 2021

Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice.

Clinical science (London, England : 1979)

Ma H,Jiang T,Tang W,Ma Z,Pu K,Xu F,Chang H,Zhao G,Gao W,Li Y,Wang Q

Fri Aug 28 00:00:00 EDT 2020

Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.

Bio-protocol

Lv T,Zhu S,Ma Y,Feng H,Wan Q

Sun Sep 20 00:00:00 EDT 2020

Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.

Bio-protocol

Lv T,Zhu S,Ma Y,Feng H,Wan Q

Sun Sep 20 00:00:00 EDT 2020

Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.

Journal of proteome research

Meng K,Lu S,Yan X,Sun Y,Gao J,Wang Y,Yin X,Sun Z,He QY

Fri Mar 06 00:00:00 EST 2020

Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.

International journal of biological sciences

Deng X,Liu J,Liu L,Sun X,Huang J,Dong J

Mon Sep 27 00:00:00 EDT 2021

Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1α in a Rat Model of Isoproterenol-Induced Cardiomyopathy.

Frontiers in pharmacology

Zhu Z,Li H,Chen W,Cui Y,Huang A,Qi X

Mon Sep 28 00:00:00 EDT 2020

Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.

Cell death & disease

Yang X,Chen G,Yu KN,Yang M,Peng S,Ma J,Qin F,Cao W,Cui S,Nie L,Han W

Mon Apr 27 00:00:00 EDT 2020

DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice.

Nature communications

Li X,Pan J,Li H,Li G,Liu X,Liu B,He Z,Peng Z,Zhang H,Li Y,Xiang X,Chai X,Yuan Y,Zheng P,Liu F,Zhang D

Fri Sep 18 00:00:00 EDT 2020

Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy.

Redox biology

Wu H,Wei H,Zhang D,Sehgal SA,Zhang D,Wang X,Qin Y,Liu L,Chen Q

Tue Sep 01 00:00:00 EDT 2020

Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise.

Journal of molecular and cellular cardiology

Moyzis AG,Lally NS,Liang W,Leon LJ,Najor RH,Orogo AM,Gustafsson ÅB

Tue Sep 01 00:00:00 EDT 2020

Lanthanum chloride impairs spatial learning and memory by inducing [Ca²⁺]_m overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.

Metallomics : integrated biometal science

Yu M,Yang J,Gao X,Sun W,Liu S,Han Y,Lu X,Jin C,Wu S,Cai Y

Wed Apr 01 00:00:00 EDT 2020

Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.

Chemosphere

Wang HW,Liu J,Wei SS,Zhao WP,Zhu SQ,Zhou BH

Sat Feb 01 00:00:00 EST 2020

DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice.

Diabetes

Xu X,Wang W,Wang Z,Lv J,Xu X,Xu J,Yang J,Zhu X,Lu Y,Duan W,Huang X,Wang J,Zhou J,Shen X

Tue Sep 01 00:00:00 EDT 2020

Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis.

Haematologica

Zhang Z,Huang Z,Ong B,Sahu C,Zeng H,Ruan HB

Sun Sep 01 00:00:00 EDT 2019

Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.

Acta pharmacologica Sinica

Deng XH,Liu JJ,Sun XJ,Dong JC,Huang JH

Wed May 01 00:00:00 EDT 2019

Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.

Acta pharmacologica Sinica

Deng XH,Liu JJ,Sun XJ,Dong JC,Huang JH

Wed May 01 00:00:00 EDT 2019

Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.

Acta pharmacologica Sinica

Deng XH,Liu JJ,Sun XJ,Dong JC,Huang JH

Wed May 01 00:00:00 EDT 2019

Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.

Acta pharmacologica Sinica

Deng XH,Liu JJ,Sun XJ,Dong JC,Huang JH

Wed May 01 00:00:00 EDT 2019

Increased Dynamin-Related Protein 1-Dependent Mitochondrial Fission Contributes to High-Fat-Diet-Induced Cardiac Dysfunction and Insulin Resistance by Elevating Tafazzin in Mouse Hearts.

Molecular nutrition & food research

Chang W,Xiao D,Ao X,Li M,Xu T,Wang J

Mon Apr 01 00:00:00 EDT 2019

Increased Dynamin-Related Protein 1-Dependent Mitochondrial Fission Contributes to High-Fat-Diet-Induced Cardiac Dysfunction and Insulin Resistance by Elevating Tafazzin in Mouse Hearts.

Molecular nutrition & food research

Chang W,Xiao D,Ao X,Li M,Xu T,Wang J

Mon Apr 01 00:00:00 EDT 2019

Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.

Bioconjugate chemistry

Du Y,Hu H,Pei X,Du K,Wei T

Wed Mar 20 00:00:00 EDT 2019

Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.

Bioconjugate chemistry

Du Y,Hu H,Pei X,Du K,Wei T

Wed Mar 20 00:00:00 EDT 2019

Brain microvascular endothelial cell exosome-mediated S100A16 up-regulation confers small-cell lung cancer cell survival in brain.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Xu ZH,Miao ZW,Jiang QZ,Gan DX,Wei XG,Xue XZ,Li JQ,Zheng F,Qin XX,Fang WG,Chen YH,Li B

Fri Feb 01 00:00:00 EST 2019

Brain microvascular endothelial cell exosome-mediated S100A16 up-regulation confers small-cell lung cancer cell survival in brain.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Xu ZH,Miao ZW,Jiang QZ,Gan DX,Wei XG,Xue XZ,Li JQ,Zheng F,Qin XX,Fang WG,Chen YH,Li B

Fri Feb 01 00:00:00 EST 2019

Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.

Human molecular genetics

Pulman J,Ruzzenente B,Bianchi L,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD

Wed May 01 00:00:00 EDT 2019

Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.

Human molecular genetics

Pulman J,Ruzzenente B,Bianchi L,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD

Wed May 01 00:00:00 EDT 2019

Effects of resveratrol on regulation on UCP2 and cardiac function in diabetic rats.

Journal of physiology and biochemistry

Diao J,Wei J,Yan R,Fan G,Lin L,Chen M

Fri Feb 01 00:00:00 EST 2019

Effects of resveratrol on regulation on UCP2 and cardiac function in diabetic rats.

Journal of physiology and biochemistry

Diao J,Wei J,Yan R,Fan G,Lin L,Chen M

Fri Feb 01 00:00:00 EST 2019

NADPH oxidase inhibitor apocynin decreases mitochondrial dysfunction and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging model in rats.

Neurochemistry international

Du ZD,Yu S,Qi Y,Qu TF,He L,Wei W,Liu K,Gong SS

Fri Mar 01 00:00:00 EST 2019

NADPH oxidase inhibitor apocynin decreases mitochondrial dysfunction and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging model in rats.

Neurochemistry international

Du ZD,Yu S,Qi Y,Qu TF,He L,Wei W,Liu K,Gong SS

Fri Mar 01 00:00:00 EST 2019

A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma.

American journal of cancer research

Li Z,Zhu T,Xu Y,Wu C,Chen J,Ren Y,Kong L,Sun S,Guo W,Wang Y,Jing C,Dong J,Zhou J,Zhang L,Shen Q,Zhou X

Thu Oct 01 00:00:00 EDT 2020

Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.

International journal of molecular medicine

Kang Y,Li Y,Zhang T,Chi Y,Liu M

Thu Aug 01 00:00:00 EDT 2019

Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response.

Nature communications

Li SZ,Shu QP,Song Y,Zhang HH,Liu Y,Jin BX,Liuyu TZ,Li C,Huang XC,Du RL,Song W,Zhong B,Zhang XD

Fri Jul 19 00:00:00 EDT 2019

GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.

Journal of physiology and biochemistry

Lv T,Hu Y,Ma Y,Zhen J,Xin W,Wan Q

Fri Nov 01 00:00:00 EDT 2019

Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes.

Oxidative medicine and cellular longevity

Huang J,Peng W,Zheng Y,Hao H,Li S,Yao Y,Ding Y,Zhang J,Lyu J,Zeng Q

Mon Dec 16 00:00:00 EST 2019

Mitochondrial DNA 3,860-bp Deletion Increases with Aging in the Auditory Nervous System of C57BL/6J Mice.

ORL; journal for oto-rhino-laryngology and its related specialties

Du ZD,He L,Tu C,Guo XA,Yu S,Liu K,Gong S

Thu Apr 30 00:00:00 EDT 2020

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.

Molecular genetics & genomic medicine

Sha Y,Liu W,Huang X,Li Y,Ji Z,Mei L,Lin S,Kong S,Lu J,Kong L,Zhu X,Lu Z,Ding L

Thu Aug 01 00:00:00 EDT 2019

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.

Molecular genetics & genomic medicine

Sha Y,Liu W,Huang X,Li Y,Ji Z,Mei L,Lin S,Kong S,Lu J,Kong L,Zhu X,Lu Z,Ding L

Thu Aug 01 00:00:00 EDT 2019

Zinc accumulation in mitochondria promotes ischemia-induced BBB disruption through Drp1-dependent mitochondria fission.

Toxicology and applied pharmacology

Qi Z,Shi W,Zhao Y,Ji X,Liu KJ

Thu Aug 15 00:00:00 EDT 2019

Mitochondria-Targeting Thermosensitive Initiator with Enhanced Anticancer Efficiency.

ACS applied bio materials

Peng M,Wang XQ,Zhang Y,Li CX,Zhang M,Cheng H,Zhang XZ

Mon Oct 21 00:00:00 EDT 2019

Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.

Cells

Tang Z,Zhang Z,Zhang H,Wang Y,Zhang Y,Zhao J,Yang H,Wang Z

Fri Dec 27 00:00:00 EST 2019

Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.

European journal of pharmacology

Yu X,Hao M,Liu Y,Ma X,Lin W,Xu Q,Zhou H,Shao N,Kuang H

Sun Dec 01 00:00:00 EST 2019

Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.

Journal of virology

Lin P,Cheng Y,Song S,Qiu J,Yi L,Cao Z,Li J,Cheng S,Wang J

Fri Nov 15 00:00:00 EST 2019

Determination of the Molecular Mechanism of Torularhodin against Hepatic Oxidative Damage by Transcriptome Analysis.

Oxidative medicine and cellular longevity

Li J,Guo Y,Cheng Y,Pi F,Yao W,Xie Y,Qian H

Fri Jan 03 00:00:00 EST 2020

NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly.

Cell research

Hou T,Zhang R,Jian C,Ding W,Wang Y,Ling S,Ma Q,Hu X,Cheng H,Wang X

Sun Sep 01 00:00:00 EDT 2019

Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure.

Oxidative medicine and cellular longevity

Wang Y,Yang F,Jiao FZ,Chen Q,Zhang WB,Wang LW,Gong ZJ

Mon Dec 16 00:00:00 EST 2019

2-D08 as a SUMOylation inhibitor induced ROS accumulation mediates apoptosis of acute myeloid leukemia cells possibly through the deSUMOylation of NOX2.

Biochemical and biophysical research communications

Zhou P,Chen X,Li M,Tan J,Zhang Y,Yuan W,Zhou J,Wang G

Tue Jun 11 00:00:00 EDT 2019

Fetal bovine serum inhibits neomycin-induced apoptosis of hair cell-like HEI-OC-1 cells by maintaining mitochondrial function.

American journal of translational research

Guan M,Zhang Y,Huang Q,He L,Fang Q,Zhang J,Gao S,Fang J,Ma Y,Su K,Gao X

Wed Sep 30 00:00:00 EDT 2020

A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.

Toxicology and applied pharmacology

Shen J,Wang J,Du J,Wang L,Zhou X,Chang X,Li Z,Zhai X,Zuo D,Wu Y

Fri Nov 15 00:00:00 EST 2019

Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.

Autophagy

Wu H,Wang Y,Li W,Chen H,Du L,Liu D,Wang X,Xu T,Liu L,Chen Q

Fri Nov 01 00:00:00 EDT 2019

MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.

Pharmacological research

Zhao X,Jin Y,Li L,Xu L,Tang Z,Qi Y,Yin L,Peng J

Thu Aug 01 00:00:00 EDT 2019

Phenylephrine Alleviates ¹³¹I Radiation Damage in Submandibular Gland Through Maintaining Mitochondrial Homeostasis.

International journal of radiation oncology, biology, physics

Wang XY,Yu J,Zhang FY,Liu KJ,Xiang B

Mon Jul 01 00:00:00 EDT 2019

Promotion of Mitochondrial Biogenesis via Activation of AMPK-PGC1α Signaling Pathway by Ginger (Zingiber officinale Roscoe) Extract, and Its Major Active Component 6-Gingerol.

Journal of food science

Deng X,Zhang S,Wu J,Sun X,Shen Z,Dong J,Huang J

Thu Aug 01 00:00:00 EDT 2019

Promotion of Mitochondrial Biogenesis via Activation of AMPK-PGC1α Signaling Pathway by Ginger (Zingiber officinale Roscoe) Extract, and Its Major Active Component 6-Gingerol.

Journal of food science

Deng X,Zhang S,Wu J,Sun X,Shen Z,Dong J,Huang J

Thu Aug 01 00:00:00 EDT 2019

The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.

Nature communications

Ma B,Cheng H,Mu C,Geng G,Zhao T,Luo Q,Ma K,Chang R,Liu Q,Gao R,Nie J,Xie J,Han J,Chen L,Ma G,Zhu Y,Chen Q

Mon Mar 04 00:00:00 EST 2019

Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.

Cell death & disease

Guo T,Liu T,Sun Y,Liu X,Xiong R,Li H,Li Z,Zhang Z,Tian Z,Tian Y

Tue Jun 11 00:00:00 EDT 2019

NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats.

Neural plasticity

Du ZD,Wei W,Yu S,Song QL,Liu K,Gong SS

Wed Jul 29 00:00:00 EDT 2020

NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats.

Neural plasticity

Du ZD,Wei W,Yu S,Song QL,Liu K,Gong SS

Wed Jul 29 00:00:00 EDT 2020

NDUFAB1 protects against obesity and insulin resistance by enhancing mitochondrial metabolism.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhang R,Hou T,Cheng H,Wang X

Sun Dec 01 00:00:00 EST 2019

SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.

Journal of Cancer

Zhang R,Wang C,Tian Y,Yao Y,Mao J,Wang H,Li Z,Xu Y,Ye M,Wang L

Thu Oct 01 00:00:00 EDT 2020

Mitochondrial respiratory chain dysfunction mediated by ROS is a primary point of fluoride-induced damage in Hepa1-6 cells.

Environmental pollution (Barking, Essex : 1987)

Wang HW,Zhang Y,Tan PP,Jia LS,Chen Y,Zhou BH

Sun Dec 01 00:00:00 EST 2019

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway.

Cell metabolism

Kurmi K,Hitosugi S,Yu J,Boakye-Agyeman F,Wiese EK,Larson TR,Dai Q,Machida YJ,Lou Z,Wang L,Boughey JC,Kaufmann SH,Goetz MP,Karnitz LM,Hitosugi T

Tue Dec 04 00:00:00 EST 2018

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway.

Cell metabolism

Kurmi K,Hitosugi S,Yu J,Boakye-Agyeman F,Wiese EK,Larson TR,Dai Q,Machida YJ,Lou Z,Wang L,Boughey JC,Kaufmann SH,Goetz MP,Karnitz LM,Hitosugi T

Tue Dec 04 00:00:00 EST 2018

Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.

Cell proliferation

Bai Z,Gao M,Xu X,Zhang H,Xu J,Guan Q,Wang Q,Du J,Li Z,Zuo D,Zhang W,Wu Y

Wed Aug 01 00:00:00 EDT 2018

Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.

Cell proliferation

Bai Z,Gao M,Xu X,Zhang H,Xu J,Guan Q,Wang Q,Du J,Li Z,Zuo D,Zhang W,Wu Y

Wed Aug 01 00:00:00 EDT 2018

PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.

The Journal of cell biology

Papadopoulos N,Lennartsson J,Heldin CH

Mon May 07 00:00:00 EDT 2018

PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.

The Journal of cell biology

Papadopoulos N,Lennartsson J,Heldin CH

Mon May 07 00:00:00 EDT 2018

Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.

Cancer science

Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y

Sat Dec 01 00:00:00 EST 2018

Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.

Cancer science

Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y

Sat Dec 01 00:00:00 EST 2018

Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.

Journal of agricultural and food chemistry

Kou G,Li Z,Wu C,Liu Y,Hu Y,Guo L,Xu X,Zhou Z

Wed Nov 14 00:00:00 EST 2018

Journal of agricultural and food chemistry

Kou G,Li Z,Wu C,Liu Y,Hu Y,Guo L,Xu X,Zhou Z

Wed Nov 14 00:00:00 EST 2018

Journal of agricultural and food chemistry

Kou G,Li Z,Wu C,Liu Y,Hu Y,Guo L,Xu X,Zhou Z

Wed Nov 14 00:00:00 EST 2018

Journal of agricultural and food chemistry

Kou G,Li Z,Wu C,Liu Y,Hu Y,Guo L,Xu X,Zhou Z

Wed Nov 14 00:00:00 EST 2018

Hyper-acetylation contributes to the sensitivity of chemo-resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A.

Journal of cellular and molecular medicine

Xu Q,Liu X,Zhu S,Hu X,Niu H,Zhang X,Zhu D,Nesa EU,Tian K,Yuan H

Thu Mar 01 00:00:00 EST 2018

Hyper-acetylation contributes to the sensitivity of chemo-resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A.

Journal of cellular and molecular medicine

Xu Q,Liu X,Zhu S,Hu X,Niu H,Zhang X,Zhu D,Nesa EU,Tian K,Yuan H

Thu Mar 01 00:00:00 EST 2018

NF-κB and JNK mediated apoptosis and G₀/G₁ arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.

Journal of ethnopharmacology

Zeng GZ,Wang Z,Zhao LM,Fan JT,Tan NH

Thu Jun 28 00:00:00 EDT 2018

NF-κB and JNK mediated apoptosis and G₀/G₁ arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.

Journal of ethnopharmacology

Zeng GZ,Wang Z,Zhao LM,Fan JT,Tan NH

Thu Jun 28 00:00:00 EDT 2018

Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.

Human mutation

Ruzzenente B,Assouline Z,Barcia G,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD

Sat Dec 01 00:00:00 EST 2018

Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.

Human mutation

Ruzzenente B,Assouline Z,Barcia G,Rio M,Boddaert N,Munnich A,Rötig A,Metodiev MD

Sat Dec 01 00:00:00 EST 2018

A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues.

Journal of cellular biochemistry

Chen D,Li X,Zhang L,Zhu M,Gao L

Thu Nov 01 00:00:00 EDT 2018

A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues.

Journal of cellular biochemistry

Chen D,Li X,Zhang L,Zhu M,Gao L

Thu Nov 01 00:00:00 EDT 2018

Modulation of sphingosine 1-phosphate (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism.

Psychopharmacology

Wu H,Zhang Q,Gao J,Sun C,Wang J,Xia W,Cao Y,Hao Y,Wu L

Thu Mar 01 00:00:00 EST 2018

Modulation of sphingosine 1-phosphate (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism.

Psychopharmacology

Wu H,Zhang Q,Gao J,Sun C,Wang J,Xia W,Cao Y,Hao Y,Wu L

Thu Mar 01 00:00:00 EST 2018

Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.

Toxicology in vitro : an international journal published in association with BIBRA

Sun DZ,Song CQ,Xu YM,Wang R,Liu W,Liu Z,Dong XS

Sat Dec 01 00:00:00 EST 2018

Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.

Toxicology in vitro : an international journal published in association with BIBRA

Sun DZ,Song CQ,Xu YM,Wang R,Liu W,Liu Z,Dong XS

Sat Dec 01 00:00:00 EST 2018

Curcumin inhibits the growth of liver cancer stem cells through the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway.

Experimental and therapeutic medicine

Wang J,Wang C,Bu G

Sun Apr 01 00:00:00 EDT 2018

Curcumin inhibits the growth of liver cancer stem cells through the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway.

Experimental and therapeutic medicine

Wang J,Wang C,Bu G

Sun Apr 01 00:00:00 EDT 2018

The dual role of poly(ADP-ribose) polymerase-1 in modulating parthanatos and autophagy under oxidative stress in rat cochlear marginal cells of the stria vascularis.

Redox biology

Jiang HY,Yang Y,Zhang YY,Xie Z,Zhao XY,Sun Y,Kong WJ

Sun Apr 01 00:00:00 EDT 2018

The dual role of poly(ADP-ribose) polymerase-1 in modulating parthanatos and autophagy under oxidative stress in rat cochlear marginal cells of the stria vascularis.

Redox biology

Jiang HY,Yang Y,Zhang YY,Xie Z,Zhao XY,Sun Y,Kong WJ

Sun Apr 01 00:00:00 EDT 2018

Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.

Cell reports

Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z

Tue Jun 05 00:00:00 EDT 2018

Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.

Cell reports

Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z

Tue Jun 05 00:00:00 EDT 2018

Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.

Journal of experimental & clinical cancer research : CR

Yuan G,Chen X,Liu Z,Wei W,Shu Q,Abou-Hamdan H,Jiang L,Li X,Chen R,Désaubry L,Zhou F,Xie D

Wed Feb 07 00:00:00 EST 2018

Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.

Journal of experimental & clinical cancer research : CR

Yuan G,Chen X,Liu Z,Wei W,Shu Q,Abou-Hamdan H,Jiang L,Li X,Chen R,Désaubry L,Zhou F,Xie D

Wed Feb 07 00:00:00 EST 2018

O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.

Cell death & disease

Wu W,Zheng X,Wang J,Yang T,Dai W,Song S,Fang L,Wang Y,Gu J

Thu Sep 20 00:00:00 EDT 2018

O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.

Cell death & disease

Wu W,Zheng X,Wang J,Yang T,Dai W,Song S,Fang L,Wang Y,Gu J

Thu Sep 20 00:00:00 EDT 2018

Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.

Cell death & disease

Aulas A,Lyons SM,Fay MM,Anderson P,Ivanov P

Tue Nov 13 00:00:00 EST 2018

The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.

The Journal of biological chemistry

Purandare N,Somayajulu M,Hüttemann M,Grossman LI,Aras S

Fri Apr 27 00:00:00 EDT 2018

The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.

The Journal of biological chemistry

Purandare N,Somayajulu M,Hüttemann M,Grossman LI,Aras S

Fri Apr 27 00:00:00 EDT 2018

SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.

EBioMedicine

Du Y,Hu H,Qu S,Wang J,Hua C,Zhang J,Wei P,He X,Hao J,Liu P,Yang F,Li T,Wei T

Mon Oct 01 00:00:00 EDT 2018

SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.

EBioMedicine

Du Y,Hu H,Qu S,Wang J,Hua C,Zhang J,Wei P,He X,Hao J,Liu P,Yang F,Li T,Wei T

Mon Oct 01 00:00:00 EDT 2018

Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.

Cell reports

Fu T,Xu Z,Liu L,Guo Q,Wu H,Liang X,Zhou D,Xiao L,Liu L,Liu Y,Zhu MS,Chen Q,Gan Z

Tue May 01 00:00:00 EDT 2018

Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.

Cell reports

Fu T,Xu Z,Liu L,Guo Q,Wu H,Liang X,Zhou D,Xiao L,Liu L,Liu Y,Zhu MS,Chen Q,Gan Z

Tue May 01 00:00:00 EDT 2018

Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.

Scientific reports

Song Y,Du Y,Zou W,Luo Y,Zhang X,Fu J

Mon Feb 19 00:00:00 EST 2018

Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.

Scientific reports

Song Y,Du Y,Zou W,Luo Y,Zhang X,Fu J

Mon Feb 19 00:00:00 EST 2018

MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca²⁺-Dependent Antioxidant Response.

Diabetes

Ji L,Liu F,Jing Z,Huang Q,Zhao Y,Cao H,Li J,Yin C,Xing J,Li F

Thu Jun 01 00:00:00 EDT 2017

MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca²⁺-Dependent Antioxidant Response.

Diabetes

Ji L,Liu F,Jing Z,Huang Q,Zhao Y,Cao H,Li J,Yin C,Xing J,Li F

Thu Jun 01 00:00:00 EDT 2017

Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation.

Oxidative medicine and cellular longevity

Deng F,Wang S,Cai S,Hu Z,Xu R,Wang J,Feng D,Zhang L

Wed Jul 11 00:00:00 EDT 2018

Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation.

Oxidative medicine and cellular longevity

Deng F,Wang S,Cai S,Hu Z,Xu R,Wang J,Feng D,Zhang L

Wed Jul 11 00:00:00 EDT 2018

Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.

Journal of agricultural and food chemistry

Su WC,Lin YF,Yu XP,Wang YX,Lin XD,Su QZ,Shen DY,Chen QX

Wed Jul 19 00:00:00 EDT 2017

Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.

Journal of agricultural and food chemistry

Su WC,Lin YF,Yu XP,Wang YX,Lin XD,Su QZ,Shen DY,Chen QX

Wed Jul 19 00:00:00 EDT 2017

Docosahexaenoic acid increases the expression of oxidative stress-induced growth inhibitor 1 through the PI3K/Akt/Nrf2 signaling pathway in breast cancer cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Tsai CH,Shen YC,Chen HW,Liu KL,Chang JW,Chen PY,Lin CY,Yao HT,Li CC

Sun Oct 01 00:00:00 EDT 2017

Docosahexaenoic acid increases the expression of oxidative stress-induced growth inhibitor 1 through the PI3K/Akt/Nrf2 signaling pathway in breast cancer cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Tsai CH,Shen YC,Chen HW,Liu KL,Chang JW,Chen PY,Lin CY,Yao HT,Li CC

Sun Oct 01 00:00:00 EDT 2017

Low-level laser therapy for beta amyloid toxicity in rat hippocampus.

Neurobiology of aging

Lu Y,Wang R,Dong Y,Tucker D,Zhao N,Ahmed ME,Zhu L,Liu TC,Cohen RM,Zhang Q

Sun Jan 01 00:00:00 EST 2017

Low-level laser therapy for beta amyloid toxicity in rat hippocampus.

Neurobiology of aging

Lu Y,Wang R,Dong Y,Tucker D,Zhao N,Ahmed ME,Zhu L,Liu TC,Cohen RM,Zhang Q

Sun Jan 01 00:00:00 EST 2017

Low-level laser therapy for beta amyloid toxicity in rat hippocampus.

Neurobiology of aging

Lu Y,Wang R,Dong Y,Tucker D,Zhao N,Ahmed ME,Zhu L,Liu TC,Cohen RM,Zhang Q

Sun Jan 01 00:00:00 EST 2017

Low-level laser therapy for beta amyloid toxicity in rat hippocampus.

Neurobiology of aging

Lu Y,Wang R,Dong Y,Tucker D,Zhao N,Ahmed ME,Zhu L,Liu TC,Cohen RM,Zhang Q

Sun Jan 01 00:00:00 EST 2017

Impaired mitochondrial fusion, autophagy, biogenesis and dysregulated lipid metabolism is associated with preeclampsia.

Experimental cell research

Zhou X,Han TL,Chen H,Baker PN,Qi H,Zhang H

Sun Oct 01 00:00:00 EDT 2017

Impaired mitochondrial fusion, autophagy, biogenesis and dysregulated lipid metabolism is associated with preeclampsia.

Experimental cell research

Zhou X,Han TL,Chen H,Baker PN,Qi H,Zhang H

Sun Oct 01 00:00:00 EDT 2017

Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.

Chemical research in toxicology

Liu Z,Wang Y,Wang Y,Dong W,Xia X,Song E,Song Y

Mon Oct 16 00:00:00 EDT 2017

Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.

Chemical research in toxicology

Liu Z,Wang Y,Wang Y,Dong W,Xia X,Song E,Song Y

Mon Oct 16 00:00:00 EDT 2017

Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway.

Acta biochimica et biophysica Sinica

Liu J,Zhang Y,Chen L,Yu F,Li X,Zhao J,Zhou S

Thu Jun 01 00:00:00 EDT 2017

Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway.

Acta biochimica et biophysica Sinica

Liu J,Zhang Y,Chen L,Yu F,Li X,Zhao J,Zhou S

Thu Jun 01 00:00:00 EDT 2017

The changes in glucose metabolism and cell proliferation in the kidneys of polycystic kidney disease mini-pig models.

Biochemical and biophysical research communications

Lian X,Zhao J,Wu X,Zhang Y,Li Q,Lin S,Bai XY,Chen X

Sat Jun 24 00:00:00 EDT 2017

The changes in glucose metabolism and cell proliferation in the kidneys of polycystic kidney disease mini-pig models.

Biochemical and biophysical research communications

Lian X,Zhao J,Wu X,Zhang Y,Li Q,Lin S,Bai XY,Chen X

Sat Jun 24 00:00:00 EDT 2017

PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.

Experimental and therapeutic medicine

Xu X,Cui Y,Cao L,Zhang Y,Yin Y,Hu X

Mon May 01 00:00:00 EDT 2017

PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.

Experimental and therapeutic medicine

Xu X,Cui Y,Cao L,Zhang Y,Yin Y,Hu X

Mon May 01 00:00:00 EDT 2017

Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.

The Journal of toxicological sciences

Miyata M,Shinno K,Kinoshita T,Kinoshita Y,Sugiura Y

Mon Mar 12 00:00:00 EDT 2018

Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.

The Journal of toxicological sciences

Miyata M,Shinno K,Kinoshita T,Kinoshita Y,Sugiura Y

Mon Mar 12 00:00:00 EDT 2018

Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Deng F,Wang S,Zhang L,Xie X,Cai S,Li H,Xie GL,Miao HL,Yang C,Liu X,Xia Z

Tue Mar 06 00:00:00 EST 2018

Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Deng F,Wang S,Zhang L,Xie X,Cai S,Li H,Xie GL,Miao HL,Yang C,Liu X,Xia Z

Tue Mar 06 00:00:00 EST 2018

Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.

Scientific reports

Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y

Thu Oct 19 00:00:00 EDT 2017

Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.

Scientific reports

Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y

Thu Oct 19 00:00:00 EDT 2017

Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.

Scientific reports

Hu D,Cao S,Zhang G,Xiao Y,Liu S,Shang Y

Thu Oct 19 00:00:00 EDT 2017

Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.

Scientific reports

Sbardella D,Tundo GR,Campagnolo L,Valacchi G,Orlandi A,Curatolo P,Borsellino G,D'Esposito M,Ciaccio C,Cesare SD,Pierro DD,Galasso C,Santarone ME,Hayek J,Coletta M,Marini S

Tue Sep 26 00:00:00 EDT 2017

Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.

Scientific reports

Sbardella D,Tundo GR,Campagnolo L,Valacchi G,Orlandi A,Curatolo P,Borsellino G,D'Esposito M,Ciaccio C,Cesare SD,Pierro DD,Galasso C,Santarone ME,Hayek J,Coletta M,Marini S

Tue Sep 26 00:00:00 EDT 2017

ABT737 induces mitochondrial pathway apoptosis and mitophagy by regulating DRP1-dependent mitochondrial fission in human ovarian cancer cells.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Yu Y,Xu L,Qi L,Wang C,Xu N,Liu S,Li S,Tian H,Liu W,Xu Y,Li Z

Fri Dec 01 00:00:00 EST 2017

CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis.

Oncotarget

Gou H,Zhao M,Xu H,Yuan J,He W,Zhu M,Ding H,Yi L,Chen J

Tue Jun 13 00:00:00 EDT 2017

CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis.

Oncotarget

Gou H,Zhao M,Xu H,Yuan J,He W,Zhu M,Ding H,Yi L,Chen J

Tue Jun 13 00:00:00 EDT 2017

A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell.

PloS one

Wang M,Kanako N,Zhang Y,Xiao X,Gao Q,Tetsuya K

Fri Sep 29 00:00:00 EDT 2017

A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell.

PloS one

Wang M,Kanako N,Zhang Y,Xiao X,Gao Q,Tetsuya K

Fri Sep 29 00:00:00 EDT 2017

Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.

Journal of cell science

Jian C,Xu F,Hou T,Sun T,Li J,Cheng H,Wang X

Tue Aug 01 00:00:00 EDT 2017

ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.

Molecular cell

Li TY,Sun Y,Liang Y,Liu Q,Shi Y,Zhang CS,Zhang C,Song L,Zhang P,Zhang X,Li X,Chen T,Huang HY,He X,Wang Y,Wu YQ,Chen S,Jiang M,Chen C,Xie C,Yang JY,Lin Y,Zhao S,Ye Z,Lin SY,Chiu DT,Lin SC

Thu May 05 00:00:00 EDT 2016

ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.

Molecular cell

Li TY,Sun Y,Liang Y,Liu Q,Shi Y,Zhang CS,Zhang C,Song L,Zhang P,Zhang X,Li X,Chen T,Huang HY,He X,Wang Y,Wu YQ,Chen S,Jiang M,Chen C,Xie C,Yang JY,Lin Y,Zhao S,Ye Z,Lin SY,Chiu DT,Lin SC

Thu May 05 00:00:00 EDT 2016

Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.

Hepatology (Baltimore, Md.)

Wang MD,Wu H,Fu GB,Zhang HL,Zhou X,Tang L,Dong LW,Qin CJ,Huang S,Zhao LH,Zeng M,Wu MC,Yan HX,Wang HY

Fri Apr 01 00:00:00 EDT 2016

Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.

Hepatology (Baltimore, Md.)

Wang MD,Wu H,Fu GB,Zhang HL,Zhou X,Tang L,Dong LW,Qin CJ,Huang S,Zhao LH,Zeng M,Wu MC,Yan HX,Wang HY

Fri Apr 01 00:00:00 EDT 2016

Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.

Autophagy

Zhang Y,Shen K,Bai Y,Lv X,Huang R,Zhang W,Chao J,Nguyen LK,Hua J,Gan G,Hu G,Yao H

Thu Sep 01 00:00:00 EDT 2016

Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.

Autophagy

Zhang Y,Shen K,Bai Y,Lv X,Huang R,Zhang W,Chao J,Nguyen LK,Hua J,Gan G,Hu G,Yao H

Thu Sep 01 00:00:00 EDT 2016

Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.

Cancer letters

Wen C,Chen J,Zhang D,Wang H,Che J,Qin Q,He L,Cai Z,Lin M,Lou Q,Huang L,Chen D,Iwamoto A,Ren D,Wang L,Lan P,Wang J,Liu H,Yang X

Wed Dec 28 00:00:00 EST 2016

Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.

Cancer letters

Wen C,Chen J,Zhang D,Wang H,Che J,Qin Q,He L,Cai Z,Lin M,Lou Q,Huang L,Chen D,Iwamoto A,Ren D,Wang L,Lan P,Wang J,Liu H,Yang X

Wed Dec 28 00:00:00 EST 2016

Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.

Annals of the New York Academy of Sciences

Niewiadomski J,Zhou JQ,Roman HB,Liu X,Hirschberger LL,Locasale JW,Stipanuk MH

Fri Jan 01 00:00:00 EST 2016

Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.

Annals of the New York Academy of Sciences

Niewiadomski J,Zhou JQ,Roman HB,Liu X,Hirschberger LL,Locasale JW,Stipanuk MH

Fri Jan 01 00:00:00 EST 2016

Oral quercetin administration transiently protects respiratory function in dystrophin-deficient mice.

The Journal of physiology

Selsby JT,Ballmann CG,Spaulding HR,Ross JW,Quindry JC

Sat Oct 15 00:00:00 EDT 2016

Oral quercetin administration transiently protects respiratory function in dystrophin-deficient mice.

The Journal of physiology

Selsby JT,Ballmann CG,Spaulding HR,Ross JW,Quindry JC

Sat Oct 15 00:00:00 EDT 2016

Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS.

Analytical and bioanalytical chemistry

Chen R,Xiao M,Gao H,Chen Y,Li Y,Liu Y,Zhang N

Mon Feb 01 00:00:00 EST 2016

Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS.

Analytical and bioanalytical chemistry

Chen R,Xiao M,Gao H,Chen Y,Li Y,Liu Y,Zhang N

Mon Feb 01 00:00:00 EST 2016

CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.

Disease markers

Han Y,Sun S,Zhao M,Zhang Z,Gong S,Gao P,Liu J,Zhou J,Ma D,Gao Q,Wu P

Mon Feb 20 00:00:00 EST 2017

CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.

Disease markers

Han Y,Sun S,Zhao M,Zhang Z,Gong S,Gao P,Liu J,Zhou J,Ma D,Gao Q,Wu P

Mon Feb 20 00:00:00 EST 2017

HDAC4 mediates IFN-γ induced disruption of energy expenditure-related gene expression by repressing SIRT1 transcription in skeletal muscle cells.

Biochimica et biophysica acta

Fang M,Fan Z,Tian W,Zhao Y,Li P,Xu H,Zhou B,Zhang L,Wu X,Xu Y

Mon Feb 01 00:00:00 EST 2016

HDAC4 mediates IFN-γ induced disruption of energy expenditure-related gene expression by repressing SIRT1 transcription in skeletal muscle cells.

Biochimica et biophysica acta

Fang M,Fan Z,Tian W,Zhao Y,Li P,Xu H,Zhou B,Zhang L,Wu X,Xu Y

Mon Feb 01 00:00:00 EST 2016

Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Li X,Song Y,Zhang P,Zhu H,Chen L,Xiao Y,Xing Y

Wed Jun 01 00:00:00 EDT 2016

Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Li X,Song Y,Zhang P,Zhu H,Chen L,Xiao Y,Xing Y

Wed Jun 01 00:00:00 EDT 2016

Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.

PloS one

Duan F,Yu Y,Guan R,Xu Z,Liang H,Hong L

Fri Aug 18 00:00:00 EDT 2017

Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.

PloS one

Duan F,Yu Y,Guan R,Xu Z,Liang H,Hong L

Fri Aug 18 00:00:00 EDT 2017

Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.

PloS one

Duan F,Yu Y,Guan R,Xu Z,Liang H,Hong L

Fri Aug 18 00:00:00 EDT 2017

Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.

Oncotarget

Zhu E,Yang Y,Zhang J,Li Y,Li C,Chen L,Sun B

Tue Dec 06 00:00:00 EST 2016

Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.

Oncotarget

Zhu E,Yang Y,Zhang J,Li Y,Li C,Chen L,Sun B

Tue Dec 06 00:00:00 EST 2016

Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle.

The Journal of biological chemistry

Liang X,Liu L,Fu T,Zhou Q,Zhou D,Xiao L,Liu J,Kong Y,Xie H,Yi F,Lai L,Vega RB,Kelly DP,Smith SR,Gan Z

Fri Dec 02 00:00:00 EST 2016

Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle.

The Journal of biological chemistry

Liang X,Liu L,Fu T,Zhou Q,Zhou D,Xiao L,Liu J,Kong Y,Xie H,Yi F,Lai L,Vega RB,Kelly DP,Smith SR,Gan Z

Fri Dec 02 00:00:00 EST 2016

Bcl-2 phosphorylation triggers autophagy switch and reduces mitochondrial damage in limb remote ischemic conditioned rats after ischemic stroke.

Translational stroke research

Qi Z,Dong W,Shi W,Wang R,Zhang C,Zhao Y,Ji X,Liu KJ,Luo Y

Mon Jun 01 00:00:00 EDT 2015

Bcl-2 phosphorylation triggers autophagy switch and reduces mitochondrial damage in limb remote ischemic conditioned rats after ischemic stroke.

Translational stroke research

Qi Z,Dong W,Shi W,Wang R,Zhang C,Zhao Y,Ji X,Liu KJ,Luo Y

Mon Jun 01 00:00:00 EDT 2015

Reduction of zinc accumulation in mitochondria contributes to decreased cerebral ischemic injury by normobaric hyperoxia treatment in an experimental stroke model.

Experimental neurology

Dong W,Qi Z,Liang J,Shi W,Zhao Y,Luo Y,Ji X,Liu KJ

Thu Oct 01 00:00:00 EDT 2015

Reduction of zinc accumulation in mitochondria contributes to decreased cerebral ischemic injury by normobaric hyperoxia treatment in an experimental stroke model.

Experimental neurology

Dong W,Qi Z,Liang J,Shi W,Zhao Y,Luo Y,Ji X,Liu KJ

Thu Oct 01 00:00:00 EDT 2015

Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Deng S,Tang S,Zhang S,Zhang C,Wang C,Zhou Y,Dai C,Xiao X

Thu Jan 01 00:00:00 EST 2015

Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Deng S,Tang S,Zhang S,Zhang C,Wang C,Zhou Y,Dai C,Xiao X

Thu Jan 01 00:00:00 EST 2015

RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells.

Apoptosis : an international journal on programmed cell death

Chen G,Cheng X,Zhao M,Lin S,Lu J,Kang J,Yu X

Thu Jan 01 00:00:00 EST 2015

RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells.

Apoptosis : an international journal on programmed cell death

Chen G,Cheng X,Zhao M,Lin S,Lu J,Kang J,Yu X

Thu Jan 01 00:00:00 EST 2015

Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.

Journal of chromatography. A

Yang XX,Xu F,Wang D,Yang ZW,Tan HR,Shang MY,Wang X,Cai SQ

Fri Sep 25 00:00:00 EDT 2015

Journal of chromatography. A

Yang XX,Xu F,Wang D,Yang ZW,Tan HR,Shang MY,Wang X,Cai SQ

Fri Sep 25 00:00:00 EDT 2015

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

Mitochondrion

Aras S,Bai M,Lee I,Springett R,Hüttemann M,Grossman LI

Thu Jan 01 00:00:00 EST 2015

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

Mitochondrion

Aras S,Bai M,Lee I,Springett R,Hüttemann M,Grossman LI

Thu Jan 01 00:00:00 EST 2015

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

Mitochondrion

Aras S,Bai M,Lee I,Springett R,Hüttemann M,Grossman LI

Thu Jan 01 00:00:00 EST 2015

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

Mitochondrion

Aras S,Bai M,Lee I,Springett R,Hüttemann M,Grossman LI

Thu Jan 01 00:00:00 EST 2015

8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Yang H,Xiong J,Luo W,Yang J,Xi T

Wed May 25 00:00:00 EDT 2016

8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Yang H,Xiong J,Luo W,Yang J,Xi T

Wed May 25 00:00:00 EDT 2016

PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.

International journal of clinical and experimental pathology

Piao MX,Bai JW,Zhang PF,Zhang YZ

Thu Mar 10 00:00:00 EST 2016

PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.

International journal of clinical and experimental pathology

Piao MX,Bai JW,Zhang PF,Zhang YZ

Thu Mar 10 00:00:00 EST 2016

FUS Interacts with HSP60 to Promote Mitochondrial Damage.

PLoS genetics

Deng J,Yang M,Chen Y,Chen X,Liu J,Sun S,Cheng H,Li Y,Bigio EH,Mesulam M,Xu Q,Du S,Fushimi K,Zhu L,Wu JY

Tue Sep 01 00:00:00 EDT 2015

FUS Interacts with HSP60 to Promote Mitochondrial Damage.

PLoS genetics

Deng J,Yang M,Chen Y,Chen X,Liu J,Sun S,Cheng H,Li Y,Bigio EH,Mesulam M,Xu Q,Du S,Fushimi K,Zhu L,Wu JY

Tue Sep 01 00:00:00 EDT 2015

PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.

Drug design, development and therapy

Yao Z,Sun B,Hong Q,Yan J,Mu D,Li J,Sheng H,Guo H

Thu Sep 15 00:00:00 EDT 2016

PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.

Drug design, development and therapy

Yao Z,Sun B,Hong Q,Yan J,Mu D,Li J,Sheng H,Guo H

Thu Sep 15 00:00:00 EDT 2016

Treatment with carnosine reduces hypoxia-ischemia brain damage in a neonatal rat model.

European journal of pharmacology

Zhang H,Guo S,Zhang L,Jia L,Zhang Z,Duan H,Zhang J,Liu J,Zhang W

Sat Mar 15 00:00:00 EDT 2014

Treatment with carnosine reduces hypoxia-ischemia brain damage in a neonatal rat model.

European journal of pharmacology

Zhang H,Guo S,Zhang L,Jia L,Zhang Z,Duan H,Zhang J,Liu J,Zhang W

Sat Mar 15 00:00:00 EDT 2014

N -methyl- N -nitrosourea-induced retinal degeneration in mice.

Experimental eye research

Chen YY,Liu SL,Hu DP,Xing YQ,Shen Y

Tue Apr 01 00:00:00 EDT 2014

N -methyl- N -nitrosourea-induced retinal degeneration in mice.

Experimental eye research

Chen YY,Liu SL,Hu DP,Xing YQ,Shen Y

Tue Apr 01 00:00:00 EDT 2014

Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells.

PloS one

Sun S,Han Y,Liu J,Fang Y,Tian Y,Zhou J,Ma D,Wu P

Thu Jan 14 00:00:00 EST 2016

Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells.

PloS one

Sun S,Han Y,Liu J,Fang Y,Tian Y,Zhou J,Ma D,Wu P

Thu Jan 14 00:00:00 EST 2016

S1 kills MCF-7/ADR cells more than MCF-7 cells: A protective mechanism of endoplasmic reticulum stress.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Song T,Liang F,Zhang Z,Liu Y,Sheng H,Xie M

Tue Oct 01 00:00:00 EDT 2013

S1 kills MCF-7/ADR cells more than MCF-7 cells: A protective mechanism of endoplasmic reticulum stress.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Song T,Liang F,Zhang Z,Liu Y,Sheng H,Xie M

Tue Oct 01 00:00:00 EDT 2013

Mitochondrial bioenergetic deficits in the hippocampi of rats with chronic ischemia-induced vascular dementia.

Neuroscience

Du J,Ma M,Zhao Q,Fang L,Chang J,Wang Y,Fei R,Song X

Tue Feb 12 00:00:00 EST 2013

Mitochondrial bioenergetic deficits in the hippocampi of rats with chronic ischemia-induced vascular dementia.

Neuroscience

Du J,Ma M,Zhao Q,Fang L,Chang J,Wang Y,Fei R,Song X

Tue Feb 12 00:00:00 EST 2013

Phosphorylation of p38 MAPK mediates hypoxic preconditioning-induced neuroprotection against cerebral ischemic injury via mitochondria translocation of Bcl-xL in mice.

Brain research

Zhao L,Liu X,Liang J,Han S,Wang Y,Yin Y,Luo Y,Li J

Fri Mar 29 00:00:00 EDT 2013

Phosphorylation of p38 MAPK mediates hypoxic preconditioning-induced neuroprotection against cerebral ischemic injury via mitochondria translocation of Bcl-xL in mice.

Brain research

Zhao L,Liu X,Liang J,Han S,Wang Y,Yin Y,Luo Y,Li J

Fri Mar 29 00:00:00 EDT 2013

alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.

Biochemical pharmacology

Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G

Thu Jul 15 00:00:00 EDT 2010

alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.

Biochemical pharmacology

Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G

Thu Jul 15 00:00:00 EDT 2010

Bioinformatics

Protein Aliases: cox iv; COX IV-1; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit IV; Cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; FLJ23483; MGC72016

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Gene Aliases: AL024441; COX; COX IV-1; COX4; COX4-1; Cox4a; COX4I1; COXIV; COXIV-1; IV-1

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UniProt ID: (Human) P13073, (Rat) P10888, (Mouse) P19783

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Entrez Gene ID: (Human) 1327, (Rat) 29445, (Mouse) 12857

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Function(s)

cytochrome-c oxidase activity protein binding oxidase

Process(es)

generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen response to nutrient hydrogen ion transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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COXIV Polyclonal Antibody

COXIV Antibody (11242-1-AP) in ICC/IF

Product Details

11242-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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