Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
CL647-15184
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
654/674 nm
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: QSLDAVEKAA FFVTLDETEE GYRSEDPDTS MDSYAKSLLH GRCYDRWFDK SFTFVVFKNG KMGLNAEHSW ADAPIVAHLW EYVMSIDSLQ LGYAEDGHCK GDINPNIPYP TRLQWDIPGE CQEVIETSLN TANLLANDVD FHSFPFVAFG KGIIKKCRTS PDAFVQLALQ LAHYKDMGKF CLTYEASMTR LFREGRTETV RSCTTESCDF VRAMVDPAQT VEQRLKLFKL ASEKHQHMYR LAMTGSGIDR HLFCLYVVSK YLAVESPFLK EVLSEPWRLS TSQTPQQQVE LFDLENNPEY VSSGGGFGPV ADDGYGVSYI LVGENLINFH ISSKFSCPET GIISQGPSSD T
Target Information
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; Carnitine palmitoyltransferase 1 alpha, liver isoform; carnitine palmitoyltransferase 1, liver; Carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase I, liver; CPT 1; CPT I; CPT1 L; CPT1-L; CPTI-L; L-CPT I; Succinyltransferase CPT1A
Gene Aliases: C730027G07; Cpt-1; CPT-Ia; CPT1; CPT1-L; CPT1A; CPTI; L-CPT1
UniProt ID: (Human) P50416, (Mouse) P97742, (Rat) P32198
Entrez Gene ID: (Human) 1374, (Mouse) 12894, (Rat) 25757
long-chain fatty acid metabolic process
glucose metabolic process
fatty acid beta-oxidation
triglyceride metabolic process
carnitine shuttle
circadian rhythm
carnitine metabolic process
response to organic cyclic compound
epithelial cell differentiation
positive regulation of fatty acid beta-oxidation
response to drug
eating behavior
regulation of insulin secretion
protein homooligomerization
cellular response to fatty acid
lipid metabolic process
fatty acid metabolic process
transport
regulation of fatty acid oxidation
regulation of fatty acid beta-oxidation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support