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Product Details
MA5-46944
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1164
Immunogen
Recombinant protein encompassing a sequence within the center region of human CPT1A. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938016
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1, liver; Carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase I, liver; CPT 1; CPT I; CPT1 L; CPT1-L; CPTI-L; L-CPT I; Succinyltransferase CPT1A
Gene Aliases: C730027G07; Cpt-1; CPT1; CPT1-L; CPT1A; CPTI; L-CPT1
UniProt ID: (Human) P50416, (Mouse) P97742
Entrez Gene ID: (Human) 1374, (Mouse) 12894
long-chain fatty acid metabolic process
glucose metabolic process
fatty acid beta-oxidation
triglyceride metabolic process
carnitine shuttle
circadian rhythm
carnitine metabolic process
response to organic cyclic compound
epithelial cell differentiation
positive regulation of fatty acid beta-oxidation
response to drug
eating behavior
regulation of insulin secretion
protein homooligomerization
cellular response to fatty acid
lipid metabolic process
fatty acid metabolic process
transport
regulation of fatty acid oxidation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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