Proteintech

CPT1B Polyclonal Antibody

CPT1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CPT1B Antibody (22170-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse heart tissue slide using 22170-1-AP (CPT1B-specific antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

CPT1B Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

CPT1B Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

22170-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 33 publications 33 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CPT1B-specific Fusion Protein Ag17840 (110-250 aa encoded by BC131570)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: FNTTRIPGK DTDVLQHLSD SRHVAVYHKG RFFKLWLYEG ARLLKPQDLE MQFQRILDDP SPPQPGEEKL AALTAGGRVE WAQARQAFFS SGKNKAALEA IERAAFFVAL DEESYSYDPE DEASLSLYGK ALLHGNCYNR WF (110-250 aa encoded by BC131570)

Target Information

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.

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Bioinformatics

Protein Aliases: Carnitine O-palmitoyltransferase 1, muscle isoform; carnitine O-palmitoyltransferase 1B; carnitine O-palmitoyltransferase I, mitochondrial muscle isoform; Carnitine O-palmitoyltransferase I, muscle isoform; Carnitine palmitoyltransferase 1 beta, muscle isoform; Carnitine palmitoyltransferase 1, muscle; Carnitine palmitoyltransferase 1B; carnitine palmitoyltransferase 1B (muscle); Carnitine palmitoyltransferase I-like protein; carnitine palmitoyltransferase Ibeta 1; carnitine palmitoyltransferase Ibeta 2; carnitine palmitoyltransferase Ibeta 3; CPT I; CPT-Ibeta 1; CPT-Ibeta 3; CPT1-M; CPTI-M; EC 2.3.1.21; FLJ55729; FLJ58750; muscle-type carnitine palmitoyltransferase I

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Gene Aliases: CPT-IB; Cpt1; CPT1-M; CPT1B; CPT1M; CPTI; CPTI-M; KIAA1670; M-CPT1; M-CPTI; MCCPT1; MCPT1

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UniProt ID: (Human) Q92523, (Mouse) Q924X2, (Rat) Q63704

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Entrez Gene ID: (Human) 1375, (Mouse) 12895, (Rat) 25756

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Function(s)

carnitine O-palmitoyltransferase activity protein binding transferase activity transferase activity, transferring acyl groups acyltransferase

Process(es)

fatty acid beta-oxidation carnitine shuttle lipid metabolic process fatty acid metabolic process transport long-chain fatty acid transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CPT1B Polyclonal Antibody

CPT1B Antibody (22170-1-AP) in IHC (P)

Product Details

22170-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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