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Product Details
12220-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CREG1 Fusion Protein Ag2901 (1-220 aa encoded by BC008628)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGLSRGSA RALLAALLAS TLLALLVSPA RGRGGRDHGD WDEASRLPPL PPREDAARVA RFVTHVSDWG ALATISTLEA VRGRPFADVL SLSDGPPGAG SGVPYFYLSP LQLSVSNLQE NPYATLTMTL AQTNFCKKHG FDPQSPLCVH IMLSGTVTKV NETEMDIAKH SLFIRHPEMK TWPSSHNWFF AKLNITNIWV LDYFGGPKIV TPEEYYNVTV Q (1-220 aa encoded by BC008628)
Target Information
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cellular repressor of E1A-stimulated genes 1; Protein CREG1
Gene Aliases: AA755314; CREG; CREG1; UNQ727/PRO1409
UniProt ID: (Human) O75629, (Mouse) O88668
Entrez Gene ID: (Human) 8804, (Mouse) 433375, (Rat) 289185
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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