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Product Details
MA5-24010
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2B
Class
Monoclonal
Type
Antibody
Clone
299133
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CREG Arg32-Gln220
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610027
Product Specific Information
In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CREG is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cellular repressor of E1A-stimulated genes 1; Protein CREG1
Gene Aliases: CREG; CREG1; UNQ727/PRO1409
UniProt ID: (Human) O75629
Entrez Gene ID: (Human) 8804
Performance Guarantee
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