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Recommended positive controls: HeLa, HeLa nucleus, mouse brain.
Predicted reactivity: Human (99%), Mouse (88%), Rat (80%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcium-responsive transactivator; SS18-like protein 1; synovial sarcoma translocation gene on chromosome 18-like 1; SYT homolog 1
Gene Aliases: A230053O16Rik; CREST; KIAA0693; LP2261; SS18L1
UniProt ID: (Human) O75177, (Mouse) Q8BW22
Entrez Gene ID: (Human) 26039, (Mouse) 269397
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