Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: CTQYQQILH RNLVYLATIA DSNQNMQSLL PAPPTQNMNL GPGALTQSGS SQGLHSQGSL SDAISTGLPP SSLLQGQIGN GPSHVSMQQT APNTLPTTSM SISGPGYSHA GPASQGVPMQ GQGTIGNYVS RTNINMQSNP VSMIQQQAAT SHYSSAQGGS QHYQGQSSIA MMGQGSQGSS MMGQRPMAPY RPSQQGSSQQ YLGQEEYYGE QYSHSQGAAE PMGQQYYPDG HGDYAYQQSS YTEQSYDRSF EESTQHYYEG GNSQYSQQQA GYQQGAAQQQ TYSQQQYPSQ QSYPGQQQGY GSAQGAPSQY PGYQQGQGQQ YGSYRAPQTA PSAQQQRPYG YEQGQYGNYQ Q (47-396 aa encoded by BC034494)
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.
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Protein Aliases: Calcium-responsive transactivator; Calcium-responsive transcription coactivator; SS18-like protein 1; synovial sarcoma translocation gene on chromosome 18-like 1; SYT homolog 1
Gene Aliases: A230053O16Rik; CREST; KIAA0693; LP2261; SS18L1
UniProt ID: (Human) O75177, (Mouse) Q8BW22, (Rat) Q91XJ0
Entrez Gene ID: (Human) 26039, (Mouse) 269397, (Rat) 192352
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