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Invitrogen
CRISP2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
CRISP2 Antibody (PA5-83187)
Relative expression in different tissues in IHC: Detection of differential expression levels of CRISP2 demonstrates antibody specificity. Immunohistochemical analysis of CRISP2 using anti-CRISP2 Polyclonal Antibody (Product #PA5-83187), shows significant staining of CRISP2 in testis and shows minimal or weak staining in endometrium tissues. The relative expression levels of CRISP2 within each tissue is sho... View More
Product Details
PA5-83187
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CRISP2. Recombinant protein control fragment (Product #RP-94742).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2790343
Product Specific Information
Immunogen sequence: GCPDDCDKGL CTNSCQYQDL LSNCDSLKNT AGCEHELLKE KCKATCLCEN
Target Information
The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 36; CRISP-2; CT36; Cysteine-rich secretory protein 2; glyceraldehyde-3-phosphate dehydrogenase-like 5; MGC111136; OTTHUMP00000016589; testicular tissue protein Li 43; testis specific protein 1 (probe H4-1 p3-1); Testis-specific protein TPX-1
Gene Aliases: CRISP-2; CRISP2; CT36; GAPDL5; TPX1; TSP1
UniProt ID: (Human) P16562
Entrez Gene ID: (Human) 7180
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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