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CSRP3 Antibody (PA5-109602) in IHC (P)
Immunohistochemistry analysis of CSRP3 in paraffin-embedded mouse heart. Samples were incubated with CSRP3 Polyclonal antibody (Product # PA5-109602) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-109602
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human CSRP3 (NP_003467.1).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855013
Product Specific Information
Immunogen sequence: MPNWGGGAKC GACEKTVYHA EEIQCNGRSF HKTCFHCMAC RKALDSTTVA AHESEIYCKV CYGRRYGPKG IGYGQGAGCL STDTGEHLGL QFQQSPKPAR SVTTSNPSKF TAKFGESEKC PRCGKSVYAA EKVMGGGKPW HKTCFRCAIC GKSLESTNVT DKDGELYCKV CYAKNFGPTG IGFGGLTQQV EKKE
Target Information
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac LIM domain protein; Cardiac LIM protein; CRP3; Cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); Cysteine-rich protein 3; LIM domain only 4; LIM domain protein, cardiac; MGC14488; MGC61993; Muscle LIM protein; muscle lim protein isoform
Gene Aliases: CLP; CMD1M; CMH12; CRP3; CSRP3; LMO4; MLP; MMLP
UniProt ID: (Human) P50461, (Mouse) P50462, (Rat) P50463
Entrez Gene ID: (Human) 8048, (Mouse) 13009, (Rat) 117505
blood vessel remodeling
regulation of the force of heart contraction
cardiac muscle hypertrophy
cellular calcium ion homeostasis
skeletal muscle tissue development
protein localization to organelle
detection of muscle stretch
positive regulation of transcription from RNA polymerase II promoter
cardiac muscle tissue development
cardiac myofibril assembly
cardiac muscle contraction
multicellular organism development
muscle organ development
positive regulation of myotube differentiation
cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
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