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Product Details
H00008048-M03
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
6D2
Immunogen
CSRP3 (NP_003467, 95 a.a. approximately 194 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: SPKPARSVTT SNPSKFTAKF GESEKCPRCG KSVYAAEKVM GGGKPWHKTC FRCAICGKSL ESTNVTDKDG ELYCKVCYAK NFGPTGIGFG GLTQQVEKKE
Target Information
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac LIM domain protein; Cardiac LIM protein; CRP3; Cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); Cysteine-rich protein 3; LIM domain only 4; LIM domain protein, cardiac; MGC14488; MGC61993; Muscle LIM protein; muscle lim protein isoform
Gene Aliases: CLP; CMD1M; CMH12; CRP3; CSRP3; LMO4; MLP
UniProt ID: (Human) P50461
Entrez Gene ID: (Human) 8048
blood vessel remodeling
regulation of the force of heart contraction
cardiac muscle hypertrophy
cellular calcium ion homeostasis
skeletal muscle tissue development
protein localization to organelle
detection of muscle stretch
positive regulation of transcription from RNA polymerase II promoter
cardiac muscle tissue development
cardiac myofibril assembly
cardiac muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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