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Product Details
H00001525-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CXADR (NP_001329.1, 1 a.a. approximately 365 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MALLLCFVLL CGVVDFARSL SITTPEEMIE KAKGETAYLP CKFTLSPEDQ GPLDIEWLIS PADNQKVDQV IILYSGDKIY DDYYPDLKGR VHFTSNDLKS GDASINVTNL QLSDIGTYQC KVKKAPGVAN KKIHLVVLVK PSGARCYVDG SEEIGSDFKI KCEPKEGSLP LQYEWQKLSD SQKMPTSWLA EMTSSVISVK NASSEYSGTY SCTVRNRVGS DQCLLRLNVV PPSNKAGLIA GAIIGTLLAL ALIGLIIFCC RKKRREEKYE KEVHHDIRED VPPPKSRTST ARSYIGSNHS SLGSMSPSNM EGYSKTQYNQ VPSEDFERTP QSPTLPPAKV AAPNLSRMGA IPVMIPAQSK DGSIV
Target Information
The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CAR; Coxsackievirus and adenovirus receptor; Coxsackievirus B-adenovirus receptor; CVB3-binding protein; HCVADR
Gene Aliases: CAR; CAR4/6; CXADR; HCAR
UniProt ID: (Human) P78310
Entrez Gene ID: (Human) 1525
mitochondrion organization
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
heart development
germ cell migration
epithelial structure maintenance
neutrophil chemotaxis
actin cytoskeleton reorganization
cell-cell junction organization
gamma-delta T cell activation
viral entry into host cell
cardiac muscle fiber development
regulation of immune response
leukocyte migration
transepithelial transport
AV node cell to bundle of His cell communication
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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