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Invitrogen
CXCL10 Recombinant Rabbit Monoclonal Antibody (5C7)
FIGURE: 1 / 1
CXCL10 Antibody (MA5-49840) in IHC (P)
Immunohistochemistry analysis with a CXCL10 monoclonal antibody (Product # MA5-49840) using a dilution of 1:100 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was inc... View More
Product Details
MA5-49840
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5C7
Immunogen
A synthesized peptide derived from human IP10
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_3092788
Target Information
IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 10 kDa interferon gamma-induced protein; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 10; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; CXC; CXC motif chemokine; CXCL; gamma IP10; Gamma-IP10; H-IP-10; interferon-inducible cytokine IP-10; M-IP-10; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10; Small-inducible cytokine B10
Gene Aliases: C7; crg-2; CXCL10; gIP-10; IFI10; INP10; IP-10; mob-1; SCYB10
UniProt ID: (Human) P02778
Entrez Gene ID: (Human) 3627
chemotaxis
inflammatory response
immune response
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
cell-cell signaling
muscle organ development
blood circulation
positive regulation of cell proliferation
response to cold
response to gamma radiation
T cell chemotaxis
regulation of T cell chemotaxis
response to auditory stimulus
negative regulation of angiogenesis
positive regulation of cAMP metabolic process
response to vitamin D
cellular response to heat
endothelial cell activation
regulation of cell proliferation
positive regulation of cAMP-mediated signaling
negative regulation of myoblast differentiation
regulation of protein kinase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of release of sequestered calcium ion into cytosol
defense response to virus
chemokine-mediated signaling pathway
cellular response to lipopolysaccharide
positive regulation of monocyte chemotaxis
regulation of endothelial tube morphogenesis
negative regulation of myoblast fusion
positive regulation of T cell migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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