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CXCL5 Antibody (BS-2549R) in IHC (P)
Paraformaldehyde-fixed, paraffin-embedded Rat Brain tissue; Antigen retrieval by boiling in sodium citrate buffer (0.01M, pH6) for 15 minutes; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20 minutes; Antibody incubation with CXCL5 Polyclonal Antibody, Unconjugated (bs-2549R) at 1:400 overnight at 4°C, followed by a conjugated secondary a... View More
Product Details
BS-2549R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat,
Mouse,
Rabbit
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse CXCL5, amino acids 51-132.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 5; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; Cytokine LIX; granulocyte chemotactic protein-2; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B, member 15; Small-inducible cytokine B5
Gene Aliases: AMCF-II; Cxcl5; ENA-78; GCP-2; LIX; Scyb5; Scyb6
UniProt ID: (Mouse) P50228
Entrez Gene ID: (Mouse) 20311
leukocyte homeostasis
cytokine production
positive regulation of leukocyte chemotaxis
chemotaxis
inflammatory response
immune response
G-protein coupled receptor signaling pathway
positive regulation of neuron projection development
organ regeneration
response to lipopolysaccharide
regulation of chemokine production
regulation of cell proliferation
positive regulation of JAK-STAT cascade
cell chemotaxis
chemokine-mediated signaling pathway
regulation of neutrophil mediated killing of gram-negative bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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