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CXCL5 Antibody (PA5-115069) in IHC (P)
Immunohistochemistry analysis of CXCL5 in rat testis tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115069) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115069
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CXCL5(Accession P42830), corresponding to amino acid residues G13-I63.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899705
Product Specific Information
Antibody detects endogenous levels of total CXCL5.
Target Information
The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 5; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; CXC; CXC motif chemokine; CXCL; Cytokine LIX; ENA-78(1-78); Epithelial-derived neutrophil-activating protein 78; granulocyte chemotactic protein-2; Neutrophil-activating peptide ENA-78; neutrophil-activating protein 78; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78); small inducible cytokine subfamily B, member 15; Small-inducible cytokine B5
Gene Aliases: AMCF-II; CXCL5; ENA-78; ENA78; GCP-2; LIX; SCYB5; Scyb6
UniProt ID: (Human) P42830, (Mouse) P50228
Entrez Gene ID: (Human) 6374, (Mouse) 20311
neutrophil mediated immunity
positive regulation of leukocyte chemotaxis
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
positive regulation of cell proliferation
response to lipopolysaccharide
cell chemotaxis
chemokine-mediated signaling pathway
leukocyte homeostasis
cytokine production
positive regulation of neuron projection development
organ regeneration
regulation of chemokine production
regulation of cell proliferation
positive regulation of JAK-STAT cascade
regulation of neutrophil mediated killing of gram-negative bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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