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Product Details
MA5-30321
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
050
Immunogen
Recombinant Human CXCL9/MIG protein (Thr23-Thr125)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2786069
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CXCL9/MIG.
Target Information
MIG, also known as CXCL9, is a T-cell chemoattractant inducible by gamma interferon that is a member of the CXC chemokine family of cytokines.This gene is mapped to 4q21. It is noted that, although the best-described activities of the chemokines are as chemotactic factors, chemokines also have an effect on T-cell activation, angiogenesis, and HIV infection. While most CXC chemokines are chemotactic for neutrophils, MIG and INP10 are unusual and similar in being CXC chemokines that are chemotactic for lymphocytes and inactive in neutrophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 9; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 9; CXC; CXC motif chemokine; CXCL; Gamma-interferon-induced monokine; HuMIG; monokine induced by gamma interferon; Monokine induced by interferon-gamma; Small-inducible cytokine B9
Gene Aliases: CMK; crg-10; CXCL9; Humig; MIG; SCYB9
UniProt ID: (Human) Q07325
Entrez Gene ID: (Human) 4283
positive regulation of leukocyte chemotaxis
chemotaxis
defense response
inflammatory response
immune response
cellular defense response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
positive regulation of cAMP metabolic process
response to lipopolysaccharide
regulation of cell proliferation
positive regulation of cAMP-mediated signaling
positive regulation of myoblast differentiation
positive regulation of release of sequestered calcium ion into cytosol
defense response to virus
cell chemotaxis
chemokine-mediated signaling pathway
positive regulation of myoblast fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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