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Product Details
H00004283-M06
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1F5
Immunogen
CXCL9 (AAH63122, 23 a.a. approximately 125 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KTT
Target Information
MIG, also known as CXCL9, is a T-cell chemoattractant inducible by gamma interferon that is a member of the CXC chemokine family of cytokines.This gene is mapped to 4q21. It is noted that, although the best-described activities of the chemokines are as chemotactic factors, chemokines also have an effect on T-cell activation, angiogenesis, and HIV infection. While most CXC chemokines are chemotactic for neutrophils, MIG and INP10 are unusual and similar in being CXC chemokines that are chemotactic for lymphocytes and inactive in neutrophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 9; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 9; CXC; CXC motif chemokine; CXCL; Gamma-interferon-induced monokine; HuMIG; monokine induced by gamma interferon; Monokine induced by interferon-gamma; Small-inducible cytokine B9
Gene Aliases: CMK; crg-10; CXCL9; Humig; MIG; SCYB9
UniProt ID: (Human) Q07325
Entrez Gene ID: (Human) 4283
positive regulation of leukocyte chemotaxis
chemotaxis
defense response
inflammatory response
immune response
cellular defense response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
positive regulation of cAMP metabolic process
response to lipopolysaccharide
regulation of cell proliferation
positive regulation of cAMP-mediated signaling
positive regulation of myoblast differentiation
positive regulation of release of sequestered calcium ion into cytosol
defense response to virus
cell chemotaxis
chemokine-mediated signaling pathway
positive regulation of myoblast fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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