Proteintech

CXCR7 Polyclonal Antibody

CXCR7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CXCR7 Antibody (20423-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 20423-1-AP ( CXCR7 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

CXCR7 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

20423-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 13 publications 13 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CXCR7 Fusion Protein Ag14247 (273-362 aa encoded by BC036661)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa.

Immunogen sequence: LLDIFSILH YIPFTCRLEH ALFTALHVTQ CLSLVHCCVN PVLYSFINRN YRYELMKAFI FKYSAKTGLT KLIDASRVSE TEYSALEQST K (273-362 aa encoded by BC036661)

Target Information

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells.

Journal of molecular medicine (Berlin, Germany)

Gohara Y,Tomonobu N,Kinoshita R,Futami J,Audebert L,Chen Y,Komalasari NLGY,Jiang F,Yoshizawa C,Murata H,Yamamoto KI,Watanabe M,Kumon H,Sakaguchi M

Sat Apr 01 00:00:00 EDT 2023

Inhibition of Angiogenesis by MiR-524-5p through Suppression of AKT and ERK Activation by Targeting CXCR7 in Colon Cancer Cells.

Journal of oncology

Li X,Li Z,Li C,Fang Y,Zhang G,Yan Y,Zhao X,Song X,Zhang Z

Tue Nov 22 00:00:00 EST 2022

The proton-activated G protein-coupled receptor GPR4 regulates the development of osteoarthritis via modulating CXCL12/CXCR7 signaling.

Cell death & disease

Li R,Guan Z,Bi S,Wang F,He L,Niu X,You Y,Liu Y,Ding Y,Siwko S,Wang N,Zhang Z,Jin Y,Luo J

Mon Feb 14 00:00:00 EST 2022

Overexpression of NNMT in Glioma Aggravates Tumor Cell Progression: An Emerging Therapeutic Target.

Cancers

Sun W,Zou Y,Cai Z,Huang J,Hong X,Liang Q,Jin W

Thu Jul 21 00:00:00 EDT 2022

KLF15 negatively regulates cardiac fibrosis by which SDF-1β attenuates cardiac fibrosis in type 2 diabetic mice.

Toxicology and applied pharmacology

Tian Y,Wang Z,Zheng X,Song W,Cai L,Rane M,Zhao Y

Wed Sep 15 00:00:00 EDT 2021

Increased tumor-infiltrating plasmacytoid dendritic cells promote cancer cell proliferation and invasion via TNF-α/NF-κB/CXCR-4 pathway in oral squamous cell carcinoma.

Journal of Cancer

Han N,Li X,Wang Y,Wang L,Zhang C,Zhang Z,Ruan M,Zhang C

Fri Apr 16 00:00:00 EDT 2021

Increased tumor-infiltrating plasmacytoid dendritic cells promote cancer cell proliferation and invasion via TNF-α/NF-κB/CXCR-4 pathway in oral squamous cell carcinoma.

Journal of Cancer

Han N,Li X,Wang Y,Wang L,Zhang C,Zhang Z,Ruan M,Zhang C

Fri Apr 16 00:00:00 EDT 2021

Interleukin-1β augments the angiogenesis of endothelial progenitor cells in an NF-κB/CXCR7-dependent manner.

Journal of cellular and molecular medicine

Fan X,He L,Dai Q,He J,Chen X,Dai X,Zhang C,Sun D,Meng X,Sun S,Huang J,Chen J,Lin L,Chen L,Tan Y,Yan X

Fri May 01 00:00:00 EDT 2020

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice.

Annals of the rheumatic diseases

Kuang L,Wu J,Su N,Qi H,Chen H,Zhou S,Xiong Y,Du X,Tan Q,Yang J,Jin M,Luo F,Ouyang J,Zhang B,Wang Z,Jiang W,Chen L,Chen S,Wang Z,Liu P,Yin L,Guo F,Deng C,Chen D,Liu C,Xie Y,Ni Z,Chen L

Wed Jan 01 00:00:00 EST 2020

The protective effects of umbilical cord-derived endothelial colony forming cells on hepatic veno-occlusive disease.

Cell biology international