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Invitrogen
CXCR7 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Product Details
PA5-27077
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 187 and 282 of Human CXCR7
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2544553
Product Specific Information
Recommended positive controls: PC-3, U87-MG, human CXCR7 transfected Mesenchymal stem cells.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Atypical chemokine receptor 3; C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 7; CC motif chemokine; CCmotif chemokine; chemokine; chemokine (C-X-C motif) receptor 7; Chemokine orphan receptor 1; CXC; CXC motif chemokine; CXC-R7; G protein-coupled receptor; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1
Gene Aliases: ACKR3; AW541270; CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1
UniProt ID: (Human) P25106, (Mouse) P56485
Entrez Gene ID: (Human) 57007, (Mouse) 12778
angiogenesis
vasculogenesis
positive regulation of defense response to virus by host
chemotaxis
cell adhesion
G-protein coupled receptor signaling pathway
viral process
receptor internalization
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
xenophagy
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
signal transduction
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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