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FIGURE: 1 / 3
Positive Control: Rat bladder tissue lysates, mouse lung tissue lysates, mouse kidney tissue.
Subcellular Location: Mitochondrion.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1,25-@dihydroxyvitamin D3 24-hydroxylase; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 24-OHase; 24R-Ohase; 25-hydroxyvitamin D-24-hydroxylase; 25-hydroxyvitamin D3 24-hydroxylase; Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase); Cytochrome P450 24A1; cytochrome P450, 24; cytochrome P450, 24a1; cytochrome P450, family 24, subfamily A, polypeptide 1; cytochrome P450, subfamily 24; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); Cytochrome P450-CC24; exo-mitochondrial protein; MGC126273; MGC126274; P450-CC24; vitamin D 24-hydroxylase; vitamin D(3) 24-hydroxylase
Gene Aliases: 24-OHase; 25-hydroxyvitaminD324-hydroxylase; CP24; Cyp-24; CYP24; CYP24A1; HCAI; HCINF1; P450-CC24; VITD12
UniProt ID: (Human) Q07973, (Mouse) Q64441, (Rat) Q09128
Entrez Gene ID: (Human) 1591, (Mouse) 13081, (Rat) 25279
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