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Product Details
11688-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CYP4A11 Fusion Protein Ag2300 (1-215 aa encoded by BC022851)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSVSVLSPS RLLGDVSGIL QAASLLILLL LLIKAVQLYL HRQWLLKALQ QFPCPPSHWL FGHIQELQQD QELQRIQKWV ETFPSACPHW LWGGKVRVQL YDPDYMKVIL GRSDPKSHGS YRFLAPWIGY GLLLLNGQTW FQHRRMLTPA FHYDILKPYV GLMADSVRVM LDKWEELLGQ DSPLEVFQHV SLMTLDTIMK CAFRHWQRAQ HSRHLP (1-215 aa encoded by B C022851)
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; alkane-1 monooxygenase; CYP4AII; CYPIVA11; CYPIVA2; Cytochrome P-450 K-2; Cytochrome P-450HK-omega; Cytochrome P450 4A11; Cytochrome P450 4A2; Cytochrome P450 K-5; cytochrome P450, family 4, subfamily A, polypeptide 11; cytochrome P450, subfamily 4A, polypeptide 11; cytochrome P450, subfamily IVA, polypeptide 11; Cytochrome P450-LA-omega 2; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; P-450 HK omega; P-450 IV4AII; P-450 K-2; P450 K-5; P450-HL-omega; P450-LA-omega 2; P450HL-omega
Gene Aliases: CP4Y; Cyp4a-2; CYP4A11; CYP4A2; CYP4AII
UniProt ID: (Human) Q02928, (Rat) P20816
Entrez Gene ID: (Human) 1579, (Rat) 24306
monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
alkane 1-monooxygenase activity
oxygen binding
heme binding
leukotriene-B4 20-monooxygenase activity
fatty acid binding
arachidonic acid monooxygenase activity
arachidonic acid 11,12-epoxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
arachidonic acid binding
arachidonic acid omega-hydroxylase activity
oxygenase
long-chain fatty acid metabolic process
renal water homeostasis
pressure natriuresis
fatty acid metabolic process
leukotriene metabolic process
arachidonic acid metabolic process
epoxygenase P450 pathway
positive regulation of icosanoid secretion
leukotriene B4 catabolic process
sodium ion homeostasis
oxidation-reduction process
omega-hydroxylase P450 pathway
kidney development
response to hormone
response to drug
linoleic acid metabolic process
icosanoid biosynthetic process
lauric acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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