Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: AQPAELSVE VPENYGGNFP LYLTKLPLPR EGAEGQIVLS GDSGKATEGP FAMDPDSGFL LVTRALDREE QAEYQLQVTL EMQDGHVLWG PQPVLVHVKD ENDQVPHFSQ AIYRARLSRG TRPGIPFLFL EASDRDEPGT ANSDLRFHIL SQAPAQPSPD MFQLEPRLGA LALSPKGSTS LDHALERTYQ LLVQVKDMGD QASGHQATAT VEVSIIESTW VSLEPIHLAE NLKVLYPHHM AQVHWSGGDV HYHLESHPPG PFEVNAEGNL YVTRELDREA QAEYLLQVRA QNSHGEDYAA PLELHVLVMD ENDNVPICPP RDPTVSIPEL SP (20-350 aa encoded by BC027912)
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cadherin; cadherin 16, KSP-cadherin; Cadherin-16; Cadherin-16 (CDH16); CDH 16; Kidney-specific cadherin; KSP-cadherin; Ksp-cadherin antibody
Gene Aliases: CDH16; UNQ695/PRO1340
UniProt ID: (Human) O75309, (Mouse) O88338
Entrez Gene ID: (Human) 1014, (Rat) 307614, (Mouse) 12556
Molecular Function:
cadherin
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