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Product Details
MA1-90591
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
SP17
Immunogen
Synthetic human calcitonin 1-32 amino acid peptide.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
tissue culture supernatant
Contains
0.09% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Wet ice
RRID
AB_2068522
Product Specific Information
Recommended positive controls: Thyroid or Medullary carcinoma.
Target Information
Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Alpha CGRP; Alpha type CGRP; Alpha-type CGRP; Calcitonin; calcitonin 1; calcitonin gene related peptide 1; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin-related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; CGRP-I; katacalcin; katacalcin (KC)
Gene Aliases: CALC1; CALCA; CGRP; CGRP-I; CGRP1; CT; KC; PCT
UniProt ID: (Human) P01258
Entrez Gene ID: (Human) 796
vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure
regulation of heart rate
monocyte chemotaxis
inflammatory response
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
embryo implantation
aging
feeding behavior
response to heat
negative regulation of ossification
negative regulation of neurological system process
activation of protein kinase activity
cellular protein metabolic process
positive regulation of adenylate cyclase activity
positive regulation of ossification
negative regulation of bone resorption
negative regulation of transcription, DNA-templated
negative regulation of smooth muscle contraction
response to pain
detection of temperature stimulus involved in sensory perception of pain
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
cellular response to tumor necrosis factor
cellular response to nerve growth factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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