Product References
Extracellular vesicles as biomarkers for AIDS-associated non-Hodgkin lymphoma risk.
Frontiers in immunology
Martínez LE,Magpantay LI,Guo Y,Hegde P,Detels R,Hussain SK,Epeldegui M
MA3-027 was used in Western Blot to suggest that EVs bearing PD-L1, CD40, TNF-RII and/or IL-6Rα could serve as biomarkers for the early detection of NHL in PLWH.
Wed Nov 01 00:00:00 EDT 2023
Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles.
Journal of cachexia, sarcopenia and muscle
Le Gall L,Duddy WJ,Martinat C,Mariot V,Connolly O,Milla V,Anakor E,Ouandaogo ZG,Millecamps S,Lainé J,Vijayakumar UG,Knoblach S,Raoul C,Lucas O,Loeffler JP,Bede P,Behin A,Blasco H,Bruneteau G,Del Mar Amador M,Devos D,Henriques A,Hesters A,Lacomblez L,Laforet P,Langlet T,Leblanc P,Le Forestier N,Maisonobe T,Meininger V,Robelin L,Salachas F,Stojkovic T,Querin G,Dumonceaux J,Butler Browne G,González De Aguilar JL,Duguez S,Pradat PF
MA3-027 was used in Western Blot to test a hypothesis that muscle vesicles may be involved in ALS pathology.
Fri Apr 01 00:00:00 EDT 2022
Anti-Human CD9 Fab Fragment Antibody Blocks the Extracellular Vesicle-Mediated Increase in Malignancy of Colon Cancer Cells.
Cells
Santos MF,Rappa G,Fontana S,Karbanová J,Aalam F,Tai D,Li Z,Pucci M,Alessandro R,Morimoto C,Corbeil D,Lorico A
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Western Blot
Wed Aug 10 00:00:00 EDT 2022
Physiactisome: A New Nanovesicle Drug Containing Heat Shock Protein 60 for Treating Muscle Wasting and Cachexia.
Cells
Di Felice V,Barone R,Trovato E,D'Amico D,Macaluso F,Campanella C,Marino Gammazza A,Muccilli V,Cunsolo V,Cancemi P,Multhoff G,Coletti D,Adamo S,Farina F,Cappello F
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Western Blot
Thu Apr 21 00:00:00 EDT 2022
Investigating heparin affinity chromatography for extracellular vesicle purification and fractionation.
Journal of chromatography. A
Barnes B,Caws T,Thomas S,Shephard AP,Corteling R,Hole P,Bracewell DG
MA3-027 was used in Western Blotting to find that heparin affinity chromatography could remove on average 98.8% and 99.0% of residual protein and DNA respectively.
Tue May 10 00:00:00 EDT 2022
The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC-II molecules.
EMBO reports
Sarango G,Richetta C,Pereira M,Kumari A,Ghosh M,Bertrand L,Pionneau C,Le Gall M,Grégoire S,Jeger-Madiot R,Rosoy E,Subra F,Delelis O,Faure M,Esclatine A,Graff-Dubois S,Stevanović S,Manoury B,Ramirez BC,Moris A
MA3-027 was used in Proximity Ligation Assay (PLA) to show that the calnexin cytosolic tail is required for this interaction.
Tue Dec 06 00:00:00 EST 2022
Late Breaking Orals.
Journal of extracellular vesicles
No authors listed
MA3-027 was used in Western Blotting to investagate a hypothesis that extracellular vesicles (EVs) released from Leishmania-infected cells (LiEVs) that contain parasite derived molecules, induce cellular responses that promote tissue remodeling.
Mon Aug 01 00:00:00 EDT 2022
Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells.
The Journal of biological chemistry
Hanna DA,Moore CM,Liu L,Yuan X,Dominic IM,Fleischhacker AS,Hamza I,Ragsdale SW,Reddi AR
MA3-027 was used in Western Blot to explain why catalytically inactive mutants of HO-2 are cytoprotective against oxidative stress.
Tue Feb 01 00:00:00 EST 2022
SNARE protein USE1 is involved in the glycosylation and the expression of mumps virus fusion protein and important for viral propagation.
PLoS pathogens
Liu Y,Katoh H,Sekizuka T,Bae C,Wakata A,Kato F,Sakata M,Yamaji T,Wang Z,Takeda M
MA3-027 was used in Immunocytochemistry-immunofluorescence to find that a SNARE subfamily protein, USE1, bound specifically to the MuV fusion (F) protein and was important for MuV propagation.
Thu Dec 01 00:00:00 EST 2022
Molecular Characterization of an Aquaporin-2 Mutation Causing Nephrogenic Diabetes Insipidus.
Frontiers in endocrinology
Li Q,Lu B,Yang J,Li C,Li Y,Chen H,Li N,Duan L,Gu F,Zhang J,Xia W
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Western Blot
Mon Dec 20 00:00:00 EST 2021
Novel missense mutations in PTCHD1 alter its plasma membrane subcellular localization and cause intellectual disability and autism spectrum disorder.
Human mutation
Halewa J,Marouillat S,Dixneuf M,Thépault RA,Ung DC,Chatron N,Gérard B,Ghoumid J,Lesca G,Till M,Smol T,Couque N,Ruaud L,Chune V,Grotto S,Verloes A,Vuillaume ML,Toutain A,Raynaud M,Laumonnier F
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunocytochemistry
Thu Jul 01 00:00:00 EDT 2021
Novel missense mutations in PTCHD1 alter its plasma membrane subcellular localization and cause intellectual disability and autism spectrum disorder.
Human mutation
Halewa J,Marouillat S,Dixneuf M,Thépault RA,Ung DC,Chatron N,Gérard B,Ghoumid J,Lesca G,Till M,Smol T,Couque N,Ruaud L,Chune V,Grotto S,Verloes A,Vuillaume ML,Toutain A,Raynaud M,Laumonnier F
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunocytochemistry
Thu Jul 01 00:00:00 EDT 2021
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
BMC cancer
Hong X,Li ZX,Hou J,Zhang HY,Zhang CY,Zhang J,Sun H,Pang LH,Wang T,Deng ZH
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunocytochemistry
Thu Jan 07 00:00:00 EST 2021
The Secreted Protein C10orf118 Is a New Regulator of Hyaluronan Synthesis Involved in Tumour-Stroma Cross-Talk.
Cancers
Caon I,D'Angelo ML,Bartolini B,Caravà E,Parnigoni A,Contino F,Cancemi P,Moretto P,Karamanos NK,Passi A,Vigetti D,Karousou E,Viola M
MA3-027 was used in Immunocytochemistry to suggest c10orf118 as a new player that influences the HA amount in breast cancer microenvironment and is associated with low aggressiveness of cancer.
Fri Mar 05 00:00:00 EST 2021
The Secreted Protein C10orf118 Is a New Regulator of Hyaluronan Synthesis Involved in Tumour-Stroma Cross-Talk.
Cancers
Caon I,D'Angelo ML,Bartolini B,Caravà E,Parnigoni A,Contino F,Cancemi P,Moretto P,Karamanos NK,Passi A,Vigetti D,Karousou E,Viola M
MA3-027 was used in Immunocytochemistry to suggest c10orf118 as a new player that influences the HA amount in breast cancer microenvironment and is associated with low aggressiveness of cancer.
Fri Mar 05 00:00:00 EST 2021
Human Mesenchymal Stromal Cell-Derived Exosomes Promote In Vitro Wound Healing by Modulating the Biological Properties of Skin Keratinocytes and Fibroblasts and Stimulating Angiogenesis.
International journal of molecular sciences
Tutuianu R,Rosca AM,Iacomi DM,Simionescu M,Titorencu I
MA3-027 was used in Western Blotting to test if MSC-derived exosomes could accelerate wound healing by enhancing the biological properties of the main cell types involved in the key phases of this process.
Wed Jun 09 00:00:00 EDT 2021
Proteomic Analysis of Circulating Extracellular Vesicles Identifies Potential Biomarkers for Lymph Node Metastasis in Oral Tongue Squamous Cell Carcinoma.
Cells
Qu X,Leung TCN,Ngai SM,Tsai SN,Thakur A,Li WK,Lee Y,Leung L,Ng TH,Yam J,Lan L,Lau EHL,Wong EWY,Chan JYK,Meehan K
MA3-027 was used in Western Blot to conclude that the shortlisted EV associated proteins described here may be useful discriminatory biomarkers for differentiating OTSCC with and without nodal disease or non-cancer controls.
Tue Aug 24 00:00:00 EDT 2021
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
EMBO reports
Iacono A,Pompa A,De Marchis F,Panfili E,Greco FA,Coletti A,Orabona C,Volpi C,Belladonna ML,Mondanelli G,Albini E,Vacca C,Gargaro M,Fallarino F,Bianchi R,De Marcos Lousa C,Mazza EM,Bicciato S,Proietti E,Milano F,Martelli MP,Iamandii IM,Graupera Garcia-Mila M,Llena Sopena J,Hawkins P,Suire S,Okkenhaug K,Stark AK,Grassi F,Bellucci M,Puccetti P,Santambrogio L,Macchiarulo A,Grohmann U,Pallotta MT
MA3-027 was used in Immunomicroscopy to investigate whether the catalytic and signaling functions of indoleamine 2,3-dioxygenase 1 are spatially segregated and elucidate the corresponding molecular mechanism involving phosphoinositide 3-kinases.
Thu Dec 03 00:00:00 EST 2020
Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS.
PLoS pathogens
Webb LG,Veloz J,Pintado-Silva J,Zhu T,Rangel MV,Mutetwa T,Zhang L,Bernal-Rubio D,Figueroa D,Carrau L,Fenutria R,Potla U,Reid SP,Yount JS,Stapleford KA,Aguirre S,Fernandez-Sesma A
MA3-027 was used in Immunocytochemistry-immunoflourescence to show Chikungunya virus interacts with and antagonizes cGAS-STING signaling.
Thu Oct 01 00:00:00 EDT 2020
Engagement of people with multiple sclerosis to enhance research into the physiological effect of hyperbaric oxygen therapy.
Multiple sclerosis and related disorders
Moore L,Eggleton P,Smerdon G,Newcombe J,Holley JE,Gutowski NJ,Smallwood M
MA3-027 was used in Immunocytochemistry to advance our understanding of the physiological effects of hyperbaric oxygen treatment on brain cells and their role in neuroinflammation.
Sat Aug 01 00:00:00 EDT 2020
Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis.
EJNMMI research
Marini C,Cossu V,Bonifacino T,Bauckneht M,Torazza C,Bruno S,Castellani P,Ravera S,Milanese M,Venturi C,Carlone S,Piccioli P,Emionite L,Morbelli S,Orengo AM,Donegani MI,Miceli A,Raffa S,Marra S,Signori A,Cortese K,Grillo F,Fiocca R,Bonanno G,Sambuceti G
MA3-027 was used in Western Blotting to assess whether enhanced [18F]-fluorodeoxyglucose (FDG) uptake predictive potential reflects the link between [18F]-fluorodeoxyglucose uptake and redox stress that has been previously reported in different tissues and disease models.
Tue Jul 07 00:00:00 EDT 2020
Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis.
EJNMMI research
Marini C,Cossu V,Bonifacino T,Bauckneht M,Torazza C,Bruno S,Castellani P,Ravera S,Milanese M,Venturi C,Carlone S,Piccioli P,Emionite L,Morbelli S,Orengo AM,Donegani MI,Miceli A,Raffa S,Marra S,Signori A,Cortese K,Grillo F,Fiocca R,Bonanno G,Sambuceti G
MA3-027 was used in Western Blotting to assess whether enhanced [18F]-fluorodeoxyglucose (FDG) uptake predictive potential reflects the link between [18F]-fluorodeoxyglucose uptake and redox stress that has been previously reported in different tissues and disease models.
Tue Jul 07 00:00:00 EDT 2020
CCDC170 affects breast cancer apoptosis through IRE1 pathway.
Aging
Wang Q,Zhao Y,Zheng H,Wang Q,Wang W,Liu B,Han H,Zhang L,Chen K
MA3-027 was used in Immunocytochemistry-immunoflourescence to showe that higher CCDC170 expression is associated with a better prognosis in breast cancer patients and that CCDC170 may promote apoptosis through the IRE1α pathway.
Thu Dec 03 00:00:00 EST 2020
CCDC170 affects breast cancer apoptosis through IRE1 pathway.
Aging
Wang Q,Zhao Y,Zheng H,Wang Q,Wang W,Liu B,Han H,Zhang L,Chen K
MA3-027 was used in Immunocytochemistry-immunoflourescence to showe that higher CCDC170 expression is associated with a better prognosis in breast cancer patients and that CCDC170 may promote apoptosis through the IRE1α pathway.
Thu Dec 03 00:00:00 EST 2020
Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells.
bioRxiv : the preprint server for biology
Kwon Y,Nukala SB,Srivastava S,Miyamoto H,Ismail NI,Rehman J,Ong SB,Lee WH,Ong SG
MA3-027 was used in Western Blotting to demonstrate that SARS-CoV-2 RNA-containing extracellular vesicles represent an indirect route of viral RNA entry into human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).
Wed Jul 01 00:00:00 EDT 2020
Heme oxygenase-2 is post-translationally regulated by heme occupancy in the catalytic site.
The Journal of biological chemistry
Liu L,Dumbrepatil AB,Fleischhacker AS,Marsh ENG,Ragsdale SW
MA3-027 was used in Immunocytochemistry-immunoflourescence to elucidate the mechanism of post-translational regulation of cellular HO2 levels by heme.
Fri Dec 11 00:00:00 EST 2020
Vps34 derived phosphatidylinositol 3-monophosphate modulates megakaryocyte maturation and proplatelet production through late endosomes/lysosomes.
Journal of thrombosis and haemostasis : JTH
Bertović I,Kurelić R,Milošević I,Bender M,Krauss M,Haucke V,Jurak Begonja A
MA3-027 was used in Immunocytochemistry-immunofluorescence to suggest that PI3P-positive LE/Lys contribute to the membrane growth and proplatelet formation in MKs by their translocation to the cell periphery and fusion with the plasma membrane.
Wed Jul 01 00:00:00 EDT 2020
Neonatal Hypocalcemic Seizures in Offspring of a Mother With Familial Hypocalciuric Hypercalcemia Type 1 (FHH1).
The Journal of clinical endocrinology and metabolism
Dharmaraj P,Gorvin CM,Soni A,Nelhans ND,Olesen MK,Boon H,Cranston T,Thakker RV,Hannan FM
MA3-027 was used in Western Blotting to characterize the range of calcitropic phenotypes in the children of a mother with FHH1.
Fri May 01 00:00:00 EDT 2020
Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing.
Disease models & mechanisms
Klaver E,Zhao P,May M,Flanagan-Steet H,Freeze HH,Gilmore R,Wells L,Contessa J,Steet R
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunocytochemistry
Wed Jun 05 00:00:00 EDT 2019
Neuronal life or death linked to depression treatment: the interplay between drugs and their stress-related outcomes relate to single or combined drug therapies.
Apoptosis : an international journal on programmed cell death
Solek P,Koszla O,Mytych J,Badura J,Chelminiak Z,Cuprys M,Fraczek J,Tabecka-Lonczynska A,Koziorowski M
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Western Blot
Tue Oct 01 00:00:00 EDT 2019
Allicin disrupts cardiac Cav1.2 channels via trafficking.
Pharmaceutical biology
Han D,Xu L,Liu P,Liu Y,Sun C,Yin Y
MA3-027 was used in Immunocytochemistry to evaluate the potential of allicin on the synthesis and trafficking of Cav1.2 channels.
Sun Dec 01 00:00:00 EST 2019
Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum.
PLoS biology
Yin Y,Garcia MR,Novak AJ,Saunders AM,Ank RS,Nam AS,Fisher LW
MA3-027 was used in Immunocytochemistry to study the role of surfeit locus protein 4 as a cargo receptor.
Wed Aug 01 00:00:00 EDT 2018
Alternative splicing variant of RHBDD2 is associated with cell stress response and breast cancer progression.
Oncology reports
Canzoneri R,Rabassa ME,Gurruchaga A,Ferretti V,Palma S,Isla-Larrain M,Croce MV,Lacunza E,Abba MC
MA3-027 was used in Immunocytochemistry-immunoflourescence to identify that tumor progression in breast cancer cells can be attributed to an alternative transcription variant of RHBDD2 that can bypass the stressful tumor microenvironment.
Wed Aug 01 00:00:00 EDT 2018
Extramitochondrial energy production in platelets.
Biology of the cell
Ravera S,Signorello MG,Bartolucci M,Ferrando S,Manni L,Caicci F,Calzia D,Panfoli I,Morelli A,Leoncini G
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Tue May 01 00:00:00 EDT 2018
A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination.
Cell research
Qiu J,Yu K,Fei X,Liu Y,Nakayasu ES,Piehowski PD,Shaw JB,Puvar K,Das C,Liu X,Luo ZQ
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Sat Jul 01 00:00:00 EDT 2017
A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination.
Cell research
Qiu J,Yu K,Fei X,Liu Y,Nakayasu ES,Piehowski PD,Shaw JB,Puvar K,Das C,Liu X,Luo ZQ
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Sat Jul 01 00:00:00 EDT 2017
cTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.
The Journal of cell biology
Fan J,Wang Y,Liu L,Zhang H,Zhang F,Shi L,Yu M,Gao F,Xu Z
MA3-027 was used in Immunocytochemistry-immunoflourescence to study the underlying mechanism of the proinsulin trafficking pathway.
Mon Dec 04 00:00:00 EST 2017
A conserved role for the ESCRT membrane budding complex in LINE retrotransposition.
PLoS genetics
Horn AV,Celic I,Dong C,Martirosyan I,Han JS
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Thu Jun 01 00:00:00 EDT 2017
Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection.
The Journal of biological chemistry
Serfass JM,Takahashi Y,Zhou Z,Kawasawa YI,Liu Y,Tsotakos N,Young MM,Tang Z,Yang L,Atkinson JM,Chroneos ZC,Wang HG
MA3-027 was used in Western Blotting to elucidate that endophilin B2 is not required for embryonic development in vivo but that endophilin B2 deficiency impairs endosomal trafficking in vitro.
Fri Jun 16 00:00:00 EDT 2017
Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response.
The Journal of biological chemistry
Willy JA,Young SK,Mosley AL,Gawrieh S,Stevens JL,Masuoka HC,Wek RC
MA3-027 was used in Western Blotting to indicate a function for IBTKα in nonalcoholic steatohepatitis that links autophagy with activation of the unfolded protein response.
Fri Aug 25 00:00:00 EDT 2017
RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.
EMBO reports
Kajiho H,Kajiho Y,Frittoli E,Confalonieri S,Bertalot G,Viale G,Di Fiore PP,Oldani A,Garre M,Beznoussenko GV,Palamidessi A,Vecchi M,Chavrier P,Perez F,Scita G
MA3-027 was used in immunocytochemistry to analyze control of MT1-MMP endocytic and E-cadherin polarized golgi trafficking to promote invasive breast cancer programs by RAB2A
Fri Jul 01 00:00:00 EDT 2016
Effects of an In-Frame Deletion of the 6k Gene Locus from the Genome of Ross River Virus.
Journal of virology
Taylor A,Melton JV,Herrero LJ,Thaa B,Karo-Astover L,Gage PW,Nelson MA,Sheng KC,Lidbury BA,Ewart GD,McInerney GM,Merits A,Mahalingam S
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Fri Apr 01 00:00:00 EDT 2016
Effects of an In-Frame Deletion of the 6k Gene Locus from the Genome of Ross River Virus.
Journal of virology
Taylor A,Melton JV,Herrero LJ,Thaa B,Karo-Astover L,Gage PW,Nelson MA,Sheng KC,Lidbury BA,Ewart GD,McInerney GM,Merits A,Mahalingam S
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Fri Apr 01 00:00:00 EDT 2016
Effects of an In-Frame Deletion of the 6k Gene Locus from the Genome of Ross River Virus.
Journal of virology
Taylor A,Melton JV,Herrero LJ,Thaa B,Karo-Astover L,Gage PW,Nelson MA,Sheng KC,Lidbury BA,Ewart GD,McInerney GM,Merits A,Mahalingam S
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Fri Apr 01 00:00:00 EDT 2016
The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport.
Oncotarget
Torgersen ML,Klokk TI,Kavaliauskiene S,Klose C,Simons K,Skotland T,Sandvig K
MA3027 was used in immunocytochemistry to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport
Tue Dec 27 00:00:00 EST 2016
Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Schaefer N,Kluck CJ,Price KL,Meiselbach H,Vornberger N,Schwarzinger S,Hartmann S,Langlhofer G,Schulz S,Schlegel N,Brockmann K,Lynch B,Becker CM,Lummis SC,Villmann C
MA3-027 was used in Immunocytochemistry to conclude that a proportion of GlyR α1 mutants can be transported to the plasma membrane but do not necessarily form functional ion channels.
Wed Jan 07 00:00:00 EST 2015
Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Schaefer N,Kluck CJ,Price KL,Meiselbach H,Vornberger N,Schwarzinger S,Hartmann S,Langlhofer G,Schulz S,Schlegel N,Brockmann K,Lynch B,Becker CM,Lummis SC,Villmann C
MA3-027 was used in Immunocytochemistry to conclude that a proportion of GlyR α1 mutants can be transported to the plasma membrane but do not necessarily form functional ion channels.
Wed Jan 07 00:00:00 EST 2015
Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Schaefer N,Kluck CJ,Price KL,Meiselbach H,Vornberger N,Schwarzinger S,Hartmann S,Langlhofer G,Schulz S,Schlegel N,Brockmann K,Lynch B,Becker CM,Lummis SC,Villmann C
MA3-027 was used in Immunocytochemistry to conclude that a proportion of GlyR α1 mutants can be transported to the plasma membrane but do not necessarily form functional ion channels.
Wed Jan 07 00:00:00 EST 2015
Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Schaefer N,Kluck CJ,Price KL,Meiselbach H,Vornberger N,Schwarzinger S,Hartmann S,Langlhofer G,Schulz S,Schlegel N,Brockmann K,Lynch B,Becker CM,Lummis SC,Villmann C
MA3-027 was used in Immunocytochemistry to conclude that a proportion of GlyR α1 mutants can be transported to the plasma membrane but do not necessarily form functional ion channels.
Wed Jan 07 00:00:00 EST 2015
Limitations of In Vivo Reprogramming to Dopaminergic Neurons via a Tricistronic Strategy.
Human gene therapy methods
Theodorou M,Rauser B,Zhang J,Prakash N,Wurst W,Schick JA
MA3-027 was used in immunohistochemistry - frozen section to identify somatic cell types in vivo that can be reprogrammed
Sat Aug 01 00:00:00 EDT 2015
Connexins modulate autophagosome biogenesis.
Nature cell biology
Bejarano E,Yuste A,Patel B,Stout RF,Spray DC,Cuervo AM
MA3-027 was used in western blot to study the regulation of autophagosome biogenesis by connexins
Thu May 01 00:00:00 EDT 2014
Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease.
Molecular cell
Wei PC,Hsieh YH,Su MI,Jiang X,Hsu PH,Lo WT,Weng JY,Jeng YM,Wang JM,Chen PL,Chang YC,Lee KF,Tsai MD,Shew JY,Lee WH
MA3-027 was used in western blot to study the role of NPGPx as an oxidative stress sensor and its role in GPR78 chaperone activity
Fri Dec 14 00:00:00 EST 2012
Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress.
Nucleic acids research
Wei PC,Lo WT,Su MI,Shew JY,Lee WH
MA3-027 was used in western blot to identify NPGPx as a novel responder to non-targeting siRNA-induced stress
Sun Jan 01 00:00:00 EST 2012
Importin beta interacts with the endoplasmic reticulum-associated degradation machinery and promotes ubiquitination and degradation of mutant alpha1-antitrypsin.
The Journal of biological chemistry
Zhong Y,Wang Y,Yang H,Ballar P,Lee JG,Ye Y,Monteiro MJ,Fang S
MA3-027 was used in western blot to investigate the role of importin beta in intracellular protein degradation process
Fri Sep 30 00:00:00 EDT 2011
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Cell
Lee JH,Yu WH,Kumar A,Lee S,Mohan PS,Peterhoff CM,Wolfe DM,Martinez-Vicente M,Massey AC,Sovak G,Uchiyama Y,Westaway D,Cuervo AM,Nixon RA
MA3-027 was used in western blot to investigate the role of presenilin 1 in Lysosomal proteolysis and autophagy
Fri Jun 25 00:00:00 EDT 2010
A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum.
The Journal of general virology
Däubner T,Fink A,Seitz A,Tenzer S,Müller J,Strand D,Seckert CK,Janssen C,Renzaho A,Grzimek NK,Simon CO,Ebert S,Reddehase MJ,Oehrlein-Karpi SA,Lemmermann NA
MA3-027 was used in western blot to identify the mechanism for the retention of a herpesvirus glycoprotein in the endoplasmic reticulum
Tue Jun 01 00:00:00 EDT 2010
The human IFN-inducible p53 target gene TRIM22 colocalizes with the centrosome independently of cell cycle phase.
Experimental cell research
Petersson J,Lönnbro P,Herr AM,Mörgelin M,Gullberg U,Drott K
MA3-027 was used in immunocytochemistry to investigate the colocalization of human IFN-inducible p53 target gene TRIM22 with the centrosome
Mon Feb 15 00:00:00 EST 2010
West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis.
Journal of virology
Medigeshi GR,Lancaster AM,Hirsch AJ,Briese T,Lipkin WI,Defilippis V,Früh K,Mason PW,Nikolich-Zugich J,Nelson JA
MA3-027 was used in western blot to study the effect of West Nile virus infection on CHOP induction and apoptosis
Mon Oct 01 00:00:00 EDT 2007
Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation.
Molecular cancer therapeutics
Marrocco DL,Tilley WD,Bianco-Miotto T,Evdokiou A,Scher HI,Rifkind RA,Marks PA,Richon VM,Butler LM
MA3-027 was used in western blot to study the effects of suberoylanilide hydroxamic acid (vorinostat) on androgen receptor expression and prostate cancer cell proliferation
Mon Jan 01 00:00:00 EST 2007
Cysteine string protein monitors late steps in cystic fibrosis transmembrane conductance regulator biogenesis.
The Journal of biological chemistry
Zhang H,Schmidt BZ,Sun F,Condliffe SB,Butterworth MB,Youker RT,Brodsky JL,Aridor M,Frizzell RA
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunocytochemistry
Fri Apr 21 00:00:00 EDT 2006
Cysteine string protein monitors late steps in cystic fibrosis transmembrane conductance regulator biogenesis.
The Journal of biological chemistry
Zhang H,Schmidt BZ,Sun F,Condliffe SB,Butterworth MB,Youker RT,Brodsky JL,Aridor M,Frizzell RA
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunocytochemistry
Fri Apr 21 00:00:00 EDT 2006
Isolation of lipid droplets from cells by density gradient centrifugation.
Current protocols in cell biology
Brasaemle DL,Wolins NE
MA3-027 was used in western blot to evaluate a density gradient centrifugation protocol for the isolation of cellular lipid droplets
Sun Jan 01 00:00:00 EST 2006
The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma.
Nucleic acids research
Chin KT,Zhou HJ,Wong CM,Lee JM,Chan CP,Qiang BQ,Yuan JG,Ng IO,Jin DY
MA3-027 was used in immunocytochemistry to demonstrate the role of the liver-enriched bZIP transcription factor CREB-H on hepatic physiology and hepatocarcinogenesis.
Tue May 03 00:00:00 EDT 2005
The stop transfer sequence of the human UDP-glucuronosyltransferase 1A determines localization to the endoplasmic reticulum by both static retention and retrieval mechanisms.
The FEBS journal
Barré L,Magdalou J,Netter P,Fournel-Gigleux S,Ouzzine M
MA3-027 was used in immunocytochemistry to study how the stop tranfer sequence regulates ER residency of UGT1A
Tue Feb 01 00:00:00 EST 2005
Interaction of transducin-alpha with LGN, a G-protein modulator expressed in photoreceptor cells.
Molecular and cellular neurosciences
Kerov VS,Natochin M,Artemyev NO
MA3-027 was used in immunohistochemistry to investigate the functions of LGN and AGS3 in photoreceptor cells
Tue Mar 01 00:00:00 EST 2005
An LQT mutant minK alters KvLQT1 trafficking.
American journal of physiology. Cell physiology
Krumerman A,Gao X,Bian JS,Melman YF,Kagan A,McDonald TV
MA3-027 was used in immunocytochemistry to study the effect of the minK LQT mutation
Tue Jun 01 00:00:00 EDT 2004
Transient calnexin interaction confers long-term stability on folded K+ channel protein in the ER.
Journal of cell science
Khanna R,Lee EJ,Papazian DM
MA3-027 was used in immunocytochemistry to investigate the endoplasmic reticulum-associated degradation of channel proteins .
Tue Jun 15 00:00:00 EDT 2004
Sec13 shuttles between the nucleus and the cytoplasm and stably interacts with Nup96 at the nuclear pore complex.
Molecular and cellular biology
Enninga J,Levay A,Fontoura BM
MA3-027 was used in western blot to study the interaction of Sec13 and Nup96 during interphase.
Wed Oct 01 00:00:00 EDT 2003
Oolemmal proteomics--identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane.
Reproductive biology and endocrinology : RB&E
Calvert ME,Digilio LC,Herr JC,Coonrod SA
MA3-027 was used in immunohistochemistry to identify highly abundant heat shock proteins and chaperone proteins in mature mouse egg proteome.
Fri Feb 14 00:00:00 EST 2003
Formation of transitory intrachain and interchain disulfide bonds accompanies the folding and oligomerization of simian virus 40 Vp1 in the cytoplasm.
Proceedings of the National Academy of Sciences of the United States of America
Li PP,Nakanishi A,Clark SW,Kasamatsu H
MA3-027 was used in immunocytochemistry to study the disulfide bond formation during simian virus 40 Vp1 oligomerization
Tue Feb 05 00:00:00 EST 2002
c-erbB-3: a nuclear protein in mammary epithelial cells.
The Journal of cell biology
Offterdinger M,Schöfer C,Weipoltshammer K,Grunt TW
MA3-027 was used in western blot to demonstrate the nuclear expression and localization of c-erbB-3 in MCF-7 cells
Mon Jun 10 00:00:00 EDT 2002
Cysteine string protein interacts with and modulates the maturation of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry
Zhang H,Peters KW,Sun F,Marino CR,Lang J,Burgoyne RD,Frizzell RA
MA3-027 was used in immunocytochemistry to investigate the role of Csp in regulating CFTR trafficking at the plasma membrane.
Fri Aug 09 00:00:00 EDT 2002
Glycosylation increases potassium channel stability and surface expression in mammalian cells.
The Journal of biological chemistry
Khanna R,Myers MP,Lainé M,Papazian DM
MA3-027 was used in immunocytochemistry to demonstrate the effect of glycosylation on Shaker protein stability and surface expression in mammalian cells.
Fri Sep 07 00:00:00 EDT 2001
CTP:phosphocholine cytidylyltransferase alpha is a cytosolic protein in pulmonary epithelial cells and tissues.
The Journal of biological chemistry
Ridsdale R,Tseu I,Wang J,Post M
MA3-027 was used in immunocytochemistry to examine the expression of CTP:phosphocholine cytidylyltransferase alpha in pulmonary epithelial cells and tissues.
Fri Dec 28 00:00:00 EST 2001
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis.
The EMBO journal
Meacham GC,Lu Z,King S,Sorscher E,Tousson A,Cyr DM
Published figure using Calnexin monoclonal antibody (Product # MA3-027) in Immunofluorescence
Mon Mar 15 00:00:00 EST 1999
ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.
The EMBO journal
Lindquist JA,Jensen ON,Mann M,Hämmerling GJ
MA3-027 was used in immunoprecipitation to discover novel factors related to the assembly of MHC class I molecules
Wed Apr 15 00:00:00 EDT 1998
Retention of unassembled components of integral membrane proteins by calnexin.
Science (New York, N.Y.)
Rajagopalan S,Xu Y,Brenner MB
MA3-027 was used in immunoprecipitation to investigate calnexin's interaction with incompletely assembled TCR components
Fri Jan 21 00:00:00 EST 1994
