Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: 293T, A431, H1299, HeLaS3.
Predicted reactivity: Mouse (93%), Rat (92%), Xenopus laevis (81%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calpain htra-3; Calpain-5; nCL-3; New calpain 3; testis tissue sperm-binding protein Li 91mP
Gene Aliases: ADNIV; CAPN5; HTRA3; nCL-3; NCL3; VRNI
UniProt ID: (Human) O15484
Entrez Gene ID: (Human) 726
Molecular Function:
cysteine protease
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