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Invitrogen
Calretinin Polyclonal Antibody (DC8)
FIGURE: 1 / 5
Calretinin Antibody (18-0211) in ICC/IF
Frontiers in cell and developmental biology 2022 -
FIGURE 3 Ednrb -/- mice lack a GABA-ergic neuron population marked by Neurod6 and Gad2 in the SI of WT mice. (A) Violin plots showing expression of the denoted GABA-ergic neuron marker genes in WT and Ednrb -/- SI. (B) Gross appearance of the stomach and SI of WT and Ednrb -/- mice. (C) , (D) High-power microscopy images showing immunostaining for the denoted proteins in the SI of WT and Ednrb -/- mice, as ... View More
Product Details
18-0211
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Clone
DC8
Immunogen
Recombinant human calretinin
Conjugate
Form
Liquid
Purification
purified
Storage buffer
PBS with 1% BSA
Contains
0.1% sodium azide
Storage conditions
2-8°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2925239
Product Specific Information
Calretinin, a calcium-binding protein with a molecular weight of 29 kD, is a member of the large family of EF-hand proteins that also includes S-100 protein. This antibody is useful for differentiating mesotheliomas from adenocarcinomas. Positive tissue: Human normal pleura lining/ malignant mesothelioma.
Expected Staining Pattern: Cytoplasmic and nuclear
Target Information
Calretinin is encoded by the CALB2 gene located on chromosome 16. It is a troponin C superfamily protein having six EF-hand structural motifs. The EF motif allows the protein to bind calcium, and function in calcium signaling, calcium buffering, and modulating neuronal excitability. Calretinin is expressed in the mesothelium, mast cells, some neural cells, hair follicles, and fat cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 29 kDa calbindin; 29kD calretinin; 29kDa calbindin; calbindin 2, (29kD, calretinin); calbindin D29K; Calretinin; CR; testicular secretory protein Li 8
Gene Aliases: CAB29; CAL2; CALB2; CR
UniProt ID: (Human) P22676
Entrez Gene ID: (Human) 794
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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