Product References
Structural Adaptation of the Excitation-Contraction Coupling Apparatus in Calsequestrin1-Null Mice during Postnatal Development.
Biology
Murzilli S,Serano M,Pietrangelo L,Protasi F,Paolini C
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Sat Jul 29 00:00:00 EDT 2023
Structural Adaptation of the Excitation-Contraction Coupling Apparatus in Calsequestrin1-Null Mice during Postnatal Development.
Biology
Murzilli S,Serano M,Pietrangelo L,Protasi F,Paolini C
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Sat Jul 29 00:00:00 EDT 2023
Housekeeping Proteins Exhibit a High Level of Expression Variability Within Control Group and Between Ischemic Human Heart Biopsies.
Journal of the American Heart Association
Colombe AS,Gerbaud P,Benitah JP,Pidoux G
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue Sep 20 00:00:00 EDT 2022
Inducible deletion of raptor and mTOR from adult skeletal muscle impairs muscle contractility and relaxation.
The Journal of physiology
Baraldo M,Zorzato S,Dondjang AHT,Geremia A,Nogara L,Dumitras AG,Canato M,Marcucci L,Nolte H,Blaauw B
PA1-913 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to elucidate the functional role of mTOR in muscle contractility.
Thu Dec 01 00:00:00 EST 2022
Anti-inflammatory effects of endothelin receptor blockade in left atrial tissue of spontaneously hypertensive rats.
International journal of cardiology. Heart & vasculature
Bukowska A,Nikonova Y,Wolke C,Lendeckel U,Kockskämper J,Goette A
PA1-913 was used in Western Blotting to investigate whether an endothelin receptor antagonist, macitentan, could reduce left atrial (LA) remodeling in arterial hypertension.
Sat Oct 01 00:00:00 EDT 2022
Reducing sarcolipin expression improves muscle metabolism in mdx mice.
American journal of physiology. Cell physiology
Balakrishnan R,Mareedu S,Babu GJ
PA1-913 was used in Western Blotting to demonstrate that reduction or ablation of SLN expression can improve muscle metabolism, reduce oxidative stress, decrease muscle pathology, and protects the mdx mice from glucose intolerance.
Tue Feb 01 00:00:00 EST 2022
Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice.
American journal of physiology. Heart and circulatory physiology
Mareedu S,Pachon R,Thilagavathi J,Fefelova N,Balakrishnan R,Niranjan N,Xie LH,Babu GJ
PA1-913 was used in Western Blotting to understand how sarcolipin deficiency in mice effects cardiac SERCA function.
Fri Jan 01 00:00:00 EST 2021
Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake.
Cell reports
Butera G,Vecellio Reane D,Canato M,Pietrangelo L,Boncompagni S,Protasi F,Rizzuto R,Reggiani C,Raffaello A
PA1-913 was used in Western Blot to elucidate the role of parvalbumin in murine muscle cells.
Tue May 04 00:00:00 EDT 2021
Phosphorylation at Serines 157 and 161 Is Necessary for Preserving Cardiac Expression Level and Functions of Sarcomeric Z-Disc Protein Telethonin.
Frontiers in physiology
Lewis HR,Eminaga S,Gautel M,Avkiran M
PA1-913 was used in Western Blot to reveal that telethonin protein turnover in vivo is regulated in a novel phosphorylation-dependent manner and suggest that C-terminal phosphorylation may protect telethonin against proteasomal degradation and preserve cardiac function during hemodynamic stress.
Wed Mar 22 00:00:00 EDT 2023
Calsequestrins New Calcium Store Markers of Adult Zebrafish Cerebellum and Optic Tectum.
Frontiers in neuroanatomy
Furlan S,Campione M,Murgia M,Mosole S,Argenton F,Volpe P,Nori A
PA1-913 was used in Immunohistochemistry to identify new endoplasmic reticulum (ER) calcium store markers in zebrafish adult brain with emphasis on cerebellum and optic tectum.
Mon Sep 28 00:00:00 EDT 2020
Calsequestrins New Calcium Store Markers of Adult Zebrafish Cerebellum and Optic Tectum.
Frontiers in neuroanatomy
Furlan S,Campione M,Murgia M,Mosole S,Argenton F,Volpe P,Nori A
PA1-913 was used in Immunohistochemistry to identify new endoplasmic reticulum (ER) calcium store markers in zebrafish adult brain with emphasis on cerebellum and optic tectum.
Mon Sep 28 00:00:00 EDT 2020
Calsequestrins New Calcium Store Markers of Adult Zebrafish Cerebellum and Optic Tectum.
Frontiers in neuroanatomy
Furlan S,Campione M,Murgia M,Mosole S,Argenton F,Volpe P,Nori A
PA1-913 was used in Immunohistochemistry to identify new endoplasmic reticulum (ER) calcium store markers in zebrafish adult brain with emphasis on cerebellum and optic tectum.
Mon Sep 28 00:00:00 EDT 2020
Lack of functional wolframin causes drop in plasmalemmal sodium-calcium exchanger type 1 expression at early stage in rat model of Wolfram syndrome.
General physiology and biophysics
Kureková S,Plaas M,Cagalinec M
PA1-913 was used in Western Blot to investigate if wolframin influences processes in the myocyte plasma membrane.
Tue Sep 01 00:00:00 EDT 2020
Structural, Pro-Inflammatory and Calcium Handling Remodeling Underlies Spontaneous Onset of Paroxysmal Atrial Fibrillation in JDP2-Overexpressing Mice.
International journal of molecular sciences
Parahuleva MS,Kockskämper J,Heger J,Grimm W,Scherer A,Bühler S,Kreutz J,Schulz R,Euler G
PA1-913 was used in Western Blotting to perform in vivo studies on JDP2-overexpressing mice to investigate the impact of JDP2 on the predisposition to spontaneous atrial fibrillation (AF).
Mon Nov 30 00:00:00 EST 2020
Structural, Pro-Inflammatory and Calcium Handling Remodeling Underlies Spontaneous Onset of Paroxysmal Atrial Fibrillation in JDP2-Overexpressing Mice.
International journal of molecular sciences
Parahuleva MS,Kockskämper J,Heger J,Grimm W,Scherer A,Bühler S,Kreutz J,Schulz R,Euler G
PA1-913 was used in Western Blotting to perform in vivo studies on JDP2-overexpressing mice to investigate the impact of JDP2 on the predisposition to spontaneous atrial fibrillation (AF).
Mon Nov 30 00:00:00 EST 2020
Inward Rectifier K+ Currents Contribute to the Proarrhythmic Electrical Phenotype of Atria Overexpressing Cyclic Adenosine Monophosphate Response Element Modulator Isoform CREM-IbΔC-X.
Journal of the American Heart Association
Pluteanu F,Seidl MD,Hamer S,Scholz B,Müller FU
PA1-913 was used in Western Blotting to investigate the regulatory role of CREM-IbΔC-X on the expression of K+ channel subunits and the corresponding K+ currents in relation to AF onset in TG atrial myocytes.
Tue Dec 01 00:00:00 EST 2020
Inward Rectifier K+ Currents Contribute to the Proarrhythmic Electrical Phenotype of Atria Overexpressing Cyclic Adenosine Monophosphate Response Element Modulator Isoform CREM-IbΔC-X.
Journal of the American Heart Association
Pluteanu F,Seidl MD,Hamer S,Scholz B,Müller FU
PA1-913 was used in Western Blotting to investigate the regulatory role of CREM-IbΔC-X on the expression of K+ channel subunits and the corresponding K+ currents in relation to AF onset in TG atrial myocytes.
Tue Dec 01 00:00:00 EST 2020
Calsequestrin Deletion Facilitates Hippocampal Synaptic Plasticity and Spatial Learning in Post-Natal Development.
International journal of molecular sciences
Ambrogini P,Lattanzi D,Di Palma M,Ciacci C,Savelli D,Galati C,Gioacchini AM,Pietrangelo L,Vallorani L,Protasi F,Cuppini R
PA1-913 was used in Western Blotting to suggest that CASQ deletion affects activity-dependent ER Ca2+ release, thus facilitating synaptic plasticity and spatial learning in post-natal development.
Fri Jul 31 00:00:00 EDT 2020
Calsequestrin Deletion Facilitates Hippocampal Synaptic Plasticity and Spatial Learning in Post-Natal Development.
International journal of molecular sciences
Ambrogini P,Lattanzi D,Di Palma M,Ciacci C,Savelli D,Galati C,Gioacchini AM,Pietrangelo L,Vallorani L,Protasi F,Cuppini R
PA1-913 was used in Western Blotting to suggest that CASQ deletion affects activity-dependent ER Ca2+ release, thus facilitating synaptic plasticity and spatial learning in post-natal development.
Fri Jul 31 00:00:00 EDT 2020
Altered calcium handling produces reentry-promoting action potential alternans in atrial fibrillation-remodeled hearts.
JCI insight
Liu T,Xiong F,Qi XY,Xiao J,Villeneuve L,Abu-Taha I,Dobrev D,Huang C,Nattel S
PA1-913 was used in Western Blotting to show reduced expression of total and phosphorylated ryanodine receptors and calsequestrin in AF and unchanged phospholamban/SERCA expression.
Tue Apr 07 00:00:00 EDT 2020
Phosphorylation of cardiac myosin-binding protein-C contributes to calcium homeostasis.
The Journal of biological chemistry
Kumar M,Haghighi K,Kranias EG,Sadayappan S
PA1-913 was used in Western Blotting to conclude that improvement of contractile deficits alone without improving calcium handling may be insufficient for effective management of heart failure.
Fri Aug 07 00:00:00 EDT 2020
TRPV4 increases cardiomyocyte calcium cycling and contractility yet contributes to damage in the aged heart following hypoosmotic stress.
Cardiovascular research
Jones JL,Peana D,Veteto AB,Lambert MD,Nourian Z,Karasseva NG,Hill MA,Lindman BR,Baines CP,Krenz M,Domeier TL
PA1-913 was used in Western Blotting to provide a new mechanism for hypoosmotic stress-induced cardiomyocyte Ca2+ entry and cell damage in the aged heart.
Tue Jan 01 00:00:00 EST 2019
TRPV4 increases cardiomyocyte calcium cycling and contractility yet contributes to damage in the aged heart following hypoosmotic stress.
Cardiovascular research
Jones JL,Peana D,Veteto AB,Lambert MD,Nourian Z,Karasseva NG,Hill MA,Lindman BR,Baines CP,Krenz M,Domeier TL
PA1-913 was used in Western Blotting to provide a new mechanism for hypoosmotic stress-induced cardiomyocyte Ca2+ entry and cell damage in the aged heart.
Tue Jan 01 00:00:00 EST 2019
Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress.
International journal of molecular sciences
van Opbergen CJM,Noorman M,Pfenniger A,Copier JS,Vermij SH,Li Z,van der Nagel R,Zhang M,de Bakker JMT,Glass AM,Mohler PJ,Taffet SM,Vos MA,van Rijen HVM,Delmar M,van Veen TAB
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Wed Aug 21 00:00:00 EDT 2019
Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2-dependent transcription in cardiac myocytes.
EMBO molecular medicine
Tóth AD,Schell R,Lévay M,Vettel C,Theis P,Haslinger C,Alban F,Werhahn S,Frischbier L,Krebs-Haupenthal J,Thomas D,Gröne HJ,Avkiran M,Katus HA,Wieland T,Backs J
PA1-913 was used in Western Blotting to link between inflammation and cardiac remodeling by de-repression of MEF2 through HDAC5 inactivation, providing new ways to treat inflammatory cardiomyopathies.
Sun Jul 01 00:00:00 EDT 2018
Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6S10F mutant.
Autophagy
Liu GS,Zhu H,Cai WF,Wang X,Jiang M,Essandoh K,Vafiadaki E,Haghighi K,Lam CK,Gardner G,Adly G,Nicolaou P,Sanoudou D,Liang Q,Rubinstein J,Fan GC,Kranias EG
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue Feb 26 00:00:00 EST 2019
Facilitation of ischaemia-induced ventricular fibrillation by catecholamines is mediated by β1 and β2 agonism in the rat heart in vitro.
British journal of pharmacology
Wilder CDE,Pavlaki N,Dursun T,Gyimah P,Caldwell-Dunn E,Ranieri A,Lewis HR,Curtis MJ
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue May 01 00:00:00 EDT 2018
Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.
Human molecular genetics
Flores DJ,Duong T,Brandenberger LO,Mitra A,Shirali A,Johnson JC,Springer D,Noguchi A,Yu ZX,Ebert SN,Ludwig A,Knollmann BC,Levin MD,Pfeifer K
PA1-913 was used in Immunohistochemistry to generate and characterise novel conditional deletion and conditional rescue mouse models to test the influence of developmental programs on the heart rate and stress-induced polymorphic ventricular tachycardia phenotypes.
Tue May 01 00:00:00 EDT 2018
The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
eLife
Makarewich CA,Munir AZ,Schiattarella GG,Bezprozvannaya S,Raguimova ON,Cho EE,Vidal AH,Robia SL,Bassel-Duby R,Olson EN
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue Oct 09 00:00:00 EDT 2018
Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation.
Frontiers in physiology
Molina CE,Abu-Taha IH,Wang Q,Roselló-Díez E,Kamler M,Nattel S,Ravens U,Wehrens XHT,Hove-Madsen L,Heijman J,Dobrev D
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue Sep 29 00:00:00 EDT 2020
Stress-induced protein S-glutathionylation and phosphorylation crosstalk in cardiac sarcomeric proteins - Impact on heart function.
International journal of cardiology
Chakouri N,Reboul C,Boulghobra D,Kleindienst A,Nottin S,Gayrard S,Roubille F,Matecki S,Lacampagne A,Cazorla O
PA1-913 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to investigate crosstalk between β-adrenergic and redox signaling in cardiac tissue.
Tue May 01 00:00:00 EDT 2018
A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure.
eLife
Pollak AJ,Liu C,Gudlur A,Mayfield JE,Dalton ND,Gu Y,Chen J,Heller Brown J,Hogan PG,Wiley SE,Peterson KL,Dixon JE
PA1-913 was used in Western Blot to show that Fam20C plays an overarching role in ER/SR Ca2+ homeostasis and cardiac pathophysiology.
Thu Dec 06 00:00:00 EST 2018
Overexpression of integrin α11 induces cardiac fibrosis in mice.
Acta physiologica (Oxford, England)
Romaine A,Sørensen IW,Zeltz C,Lu N,Erusappan PM,Melleby AO,Zhang L,Bendiksen B,Robinson EL,Aronsen JM,Herum KM,Danielsen HE,Sjaastad I,Christensen G,Gullberg D
PA1-913 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to report for the first time that overexpression of integrin α11 induces cardiac fibrosis and left ventricular hypertrophy.
Thu Feb 01 00:00:00 EST 2018
T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.
Cardiovascular research
Schobesberger S,Wright P,Tokar S,Bhargava A,Mansfield C,Glukhov AV,Poulet C,Buzuk A,Monszpart A,Sikkel M,Harding SE,Nikolaev VO,Lyon AR,Gorelik J
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Thu Jun 01 00:00:00 EDT 2017
The TRPM4 channel is functionally important for the beneficial cardiac remodeling induced by endurance training.
Journal of muscle research and cell motility
Gueffier M,Zintz J,Lambert K,Finan A,Aimond F,Chakouri N,Hédon C,Granier M,Launay P,Thireau J,Richard S,Demion M
PA1913 was used in western blot to test if the TRPM4 channel contributes to physiological cardiac hypertrophy
Wed Feb 01 00:00:00 EST 2017
A chemical chaperone improves muscle function in mice with a RyR1 mutation.
Nature communications
Lee CS,Hanna AD,Wang H,Dagnino-Acosta A,Joshi AD,Knoblauch M,Xia Y,Georgiou DK,Xu J,Long C,Amano H,Reynolds C,Dong K,Martin JC,Lagor WR,Rodney GG,Sahin E,Sewry C,Hamilton SL
PA1913 was used in immunohistochemistry and western blot to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease
Fri Mar 24 00:00:00 EDT 2017
A chemical chaperone improves muscle function in mice with a RyR1 mutation.
Nature communications
Lee CS,Hanna AD,Wang H,Dagnino-Acosta A,Joshi AD,Knoblauch M,Xia Y,Georgiou DK,Xu J,Long C,Amano H,Reynolds C,Dong K,Martin JC,Lagor WR,Rodney GG,Sahin E,Sewry C,Hamilton SL
PA1913 was used in immunohistochemistry and western blot to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease
Fri Mar 24 00:00:00 EDT 2017
Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis.
Acta neuropathologica communications
Amici DR,Pinal-Fernandez I,Mázala DA,Lloyd TE,Corse AM,Christopher-Stine L,Mammen AL,Chin ER
PA1913 was used in western blot to determine the role of calcium regulation in sporadic inclusion body myositis
Wed Mar 22 00:00:00 EDT 2017
Genotype-Dependent and -Independent Calcium Signaling Dysregulation in Human Hypertrophic Cardiomyopathy.
Circulation
Helms AS,Alvarado FJ,Yob J,Tang VT,Pagani F,Russell MW,Valdivia HH,Day SM
PA1913 was used in western blot to discuss how mutations in sarcomere genes may result in altered calcium signaling and heart defects
Tue Nov 29 00:00:00 EST 2016
The angiotensin receptor-associated protein Atrap is a stimulator of the cardiac Ca2+-ATPase SERCA2a.
Cardiovascular research
Mederle K,Gess B,Pluteanu F,Plackic J,Tiefenbach KJ,Grill A,Kockskämper J,Castrop H
PA1-913 was used in Western Blotting to determine the role of angiotensin II type 1 receptor- associated protein in the heart.
Wed Jun 01 00:00:00 EDT 2016
The maintenance ability and Ca2+ availability of skeletal muscle are enhanced by sildenafil.
Experimental & molecular medicine
Huang M,Lee KJ,Kim KJ,Ahn MK,Cho CH,Kim DH,Lee EH
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Fri Dec 09 00:00:00 EST 2016
Cannabinoid signalling inhibits sarcoplasmic Ca2+ release and regulates excitation-contraction coupling in mammalian skeletal muscle.
The Journal of physiology
Oláh T,Bodnár D,Tóth A,Vincze J,Fodor J,Reischl B,Kovács A,Ruzsnavszky O,Dienes B,Szentesi P,Friedrich O,Csernoch L
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Thu Dec 15 00:00:00 EST 2016
Acyl CoA synthetase-1 links facilitated long chain fatty acid uptake to intracellular metabolic trafficking differently in hearts of male versus female mice.
Journal of molecular and cellular cardiology
Goldenberg JR,Wang X,Lewandowski ED
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Sun May 01 00:00:00 EDT 2016
Heterozygous deletion of sarcolipin maintains normal cardiac function.
American journal of physiology. Heart and circulatory physiology
Shimura D,Kusakari Y,Sasano T,Nakashima Y,Nakai G,Jiao Q,Jin M,Yokota T,Ishikawa Y,Nakano A,Goda N,Minamisawa S
PA1-913 was used in western blot to maintain cardiac function through a heterozygous deletion of sarcolipin
Fri Jan 01 00:00:00 EST 2016
Development of a high-affinity peptide that prevents phospholemman (PLM) inhibition of the sodium/calcium exchanger 1 (NCX1).
The Biochemical journal
Wanichawan P,Hodne K,Hafver TL,Lunde M,Martinsen M,Louch WE,Sejersted OM,Carlson CR
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Mon Aug 01 00:00:00 EDT 2016
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman.
The Journal of biological chemistry
Hafver TL,Hodne K,Wanichawan P,Aronsen JM,Dalhus B,Lunde PK,Lunde M,Martinsen M,Enger UH,Fuller W,Sjaastad I,Louch WE,Sejersted OM,Carlson CR
PA1-913 was used in western blot to research how protein phosphatase 1c associates with cardiac sodium calcium exchanger 1
Fri Feb 26 00:00:00 EST 2016
Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization.
PloS one
Ramratnam M,Salama G,Sharma RK,Wang DW,Smith SH,Banerjee SK,Huang XN,Gifford LM,Pruce ML,Gabris BE,Saba S,Shroff SG,Ahmad F
PA1913 was used in western blot to study mouse models of dilated cardiomyopathy to study calcium signaling
Fri Jul 07 00:00:00 EDT 2017
Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I.
Circulation. Heart failure
Carley AN,Taglieri DM,Bi J,Solaro RJ,Lewandowski ED
PA1-913 was used in western blot to study the metabolic responses during chronic pressure overloads in mouse hearts expressing ssTnI
Thu Jan 01 00:00:00 EST 2015
Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.
Skeletal muscle
Lee CS,Dagnino-Acosta A,Yarotskyy V,Hanna A,Lyfenko A,Knoblauch M,Georgiou DK,Poché RA,Swank MW,Long C,Ismailov II,Lanner J,Tran T,Dong K,Rodney GG,Dickinson ME,Beeton C,Zhang P,Dirksen RT,Hamilton SL
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Thu Feb 26 00:00:00 EST 2015
p11 modulates calcium handling through 5-HT₄R pathway in rat ventricular cardiomyocytes.
Cell calcium
Meschin P,Demion M,Cazorla O,Finan A,Thireau J,Richard S,Lacampagne A
PA1-913 was used in western blot to test if p11 regulates the serotonin receptor 4 pathway in the heart
Tue Dec 01 00:00:00 EST 2015
Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation.
FEBS letters
Van B,Nishi M,Komazaki S,Ichimura A,Kakizawa S,Nakanaga K,Aoki J,Park KH,Ma J,Ueyama T,Ogata T,Maruyama N,Takeshima H
PA1-913 was used in western blot to investigate Mitsugumin 56 in skeletal muscle maturation using knockout mice
Tue Apr 28 00:00:00 EDT 2015
Sox9 expression in canine epithelial skin tumors.
European journal of histochemistry : EJH
Fantinato E,Milani L,Sironi G
PA1-913 was used in western blot to determine Sox9 expression in eleven different types of canine skin neoplasms
Thu Jul 09 00:00:00 EDT 2015
The Effect of SERCA1b Silencing on the Differentiation and Calcium Homeostasis of C2C12 Skeletal Muscle Cells.
PloS one
Tóth A,Fodor J,Vincze J,Oláh T,Juhász T,Zákány R,Csernoch L,Zádor E
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Wed Jan 13 00:00:00 EST 2016
Expression of calcium-buffering proteins in rat intrinsic laryngeal muscles.
Physiological reports
Ferretti R,Marques MJ,Khurana TS,Santo Neto H
PA1-913 was used in western blot to examine calcium-related proteins in the intrinsic laryngeal muscles, cricothyroid, and tibialis anterior muscles from male Sprague-Dawley rats
Mon Jun 01 00:00:00 EDT 2015
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
Frontiers in physiology
De Andrade PB,Neff LA,Strosova MK,Arsenijevic D,Patthey-Vuadens O,Scapozza L,Montani JP,Ruegg UT,Dulloo AG,Dorchies OM
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Wed Oct 07 00:00:00 EDT 2015
Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy.
Molecular bioSystems
Gehmlich K,Dodd MS,Allwood JW,Kelly M,Bellahcene M,Lad HV,Stockenhuber A,Hooper C,Ashrafian H,Redwood CS,Carrier L,Dunn WB
PA1-913 was used in western blot to determine the effect of perhexiline treatment on the cardiac metabolome in wild type and Mybpc3-targeted knock-in mice
Sun Feb 01 00:00:00 EST 2015
Effectiveness of gene delivery systems for pluripotent and differentiated cells.
Molecular therapy. Methods & clinical development
Rapti K,Stillitano F,Karakikes I,Nonnenmacher M,Weber T,Hulot JS,Hajjar RJ
PA1-913 was used in western blot to compare the transduction efficiency of recombinant adeno-associated vectors, adenoviruses, and lentiviral vectors in human embryonic stem cells, human induced pluripotent stem cells, and the derived cardiomyocytes.
Mon Jun 08 00:00:00 EDT 2015
Suppression of Early and Late Afterdepolarizations by Heterozygous Knockout of the Na+/Ca2+ Exchanger in a Murine Model.
Circulation. Arrhythmia and electrophysiology
Bögeholz N,Pauls P,Bauer BK,Schulte JS,Dechering DG,Frommeyer G,Kirchhefer U,Goldhaber JI,Müller FU,Eckardt L,Pott C
PA1-913 was used in Western Blotting to demonstrate that genetic inhibition of NCX protects against afterdepolarizations and to investigate the underlying mechanisms.
Thu Oct 01 00:00:00 EDT 2015
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias.
Nature medicine
Chen W,Wang R,Chen B,Zhong X,Kong H,Bai Y,Zhou Q,Xie C,Zhang J,Guo A,Tian X,Jones PP,O'Mara ML,Liu Y,Mi T,Zhang L,Bolstad J,Semeniuk L,Cheng H,Zhang J,Chen J,Tieleman DP,Gillis AM,Duff HJ,Fill M,Song LS,Chen SR
PA1-913 was used in western blot to study the role of the ryanodine receptor store-sensing gate in ventricular tachyarrhythmias
Sat Feb 01 00:00:00 EST 2014
Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation.
Circulation
Voigt N,Heijman J,Wang Q,Chiang DY,Li N,Karck M,Wehrens XHT,Nattel S,Dobrev D
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue Jan 14 00:00:00 EST 2014
Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age.
Circulation
Denegri M,Bongianino R,Lodola F,Boncompagni S,De Giusti VC,Avelino-Cruz JE,Liu N,Persampieri S,Curcio A,Esposito F,Pietrangelo L,Marty I,Villani L,Moyaho A,Baiardi P,Auricchio A,Protasi F,Napolitano C,Priori SG
PA1-913 was used in Western Blotting to investigate the efficacy and durability of viral gene transfer of wild-type calsequestrin 2 in a catecholaminergic polymorphic ventricular tachycardia knock-in mouse model carrying the CASQ2 R33Q mutation.
Tue Jun 24 00:00:00 EDT 2014
Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release.
Circulation. Arrhythmia and electrophysiology
Chiang DY,Kongchan N,Beavers DL,Alsina KM,Voigt N,Neilson JR,Jakob H,Martin JF,Dobrev D,Wehrens XH,Li N
PA1-913 was used in western blot to study the loss of thd miR-106b-25 cluster in the pathogenesis of atrial fibrillation
Mon Dec 01 00:00:00 EST 2014
Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.
PloS one
Sivagangabalan G,Nazzari H,Bignolais O,Maguy A,Naud P,Farid T,Massé S,Gaborit N,Varro A,Nair K,Backx P,Vigmond E,Nattel S,Demolombe S,Nanthakumar K
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Fri Oct 17 00:00:00 EDT 2014
Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure.
The Journal of biological chemistry
Wanichawan P,Hafver TL,Hodne K,Aronsen JM,Lunde IG,Dalhus B,Lunde M,Kvaløy H,Louch WE,Tønnessen T,Sjaastad I,Sejersted OM,Carlson CR
PA1-913 was used in western blot to determine the relationship between calpain and NCX1 in the heart
Fri Dec 05 00:00:00 EST 2014
Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance.
Nature medicine
Wang W,Barnabei MS,Asp ML,Heinis FI,Arden E,Davis J,Braunlin E,Li Q,Davis JP,Potter JD,Metzger JM
PA1-913 was used in western blot to study the beneficial effects on cardiac performance of a EF-hand motif mutation that creates a highly delayed Ca2(+) buffer
Fri Mar 01 00:00:00 EST 2013
The anticancer drug tamoxifen counteracts the pathology in a mouse model of duchenne muscular dystrophy.
The American journal of pathology
Dorchies OM,Reutenauer-Patte J,Dahmane E,Ismail HM,Petermann O,Patthey- Vuadens O,Comyn SA,Gayi E,Piacenza T,Handa RJ,Décosterd LA,Ruegg UT
PA1-913 was used in western blot to study the beneficial effects of tamoxifen on muscle force and structure in a murine model of Duchenne muscular dystrophy
Fri Feb 01 00:00:00 EST 2013
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart.
The FEBS journal
Strand ME,Herum KM,Rana ZA,Skrbic B,Askevold ET,Dahl CP,Vistnes M,Hasic A,Kvaløy H,Sjaastad I,Carlson CR,Tønnessen T,Gullestad L,Christensen G,Lunde IG
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Wed May 01 00:00:00 EDT 2013
Knockout of the Na,K-ATPase α2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction.
American journal of physiology. Heart and circulatory physiology
Rindler TN,Lasko VM,Nieman ML,Okada M,Lorenz JN,Lingrel JB
PA1-913 was used in western blot to study the role of cardiac myocyte Na,K-ATPase-alpha 2 in the devopment of cardiac dysfunction in response to pressure overload-induced
Mon Apr 15 00:00:00 EDT 2013
Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophy.
Journal of muscle research and cell motility
Schneider JS,Shanmugam M,Gonzalez JP,Lopez H,Gordan R,Fraidenraich D,Babu GJ
PA1-913 was used in western blot to study changes in sarcolipin levels and SR Ca(2+) metabolism in skeletal muscle in a murine model of Duchenne muscular dystrophy
Sun Dec 01 00:00:00 EST 2013
The PEG-switch assay: a fast semi-quantitative method to determine protein reversible cysteine oxidation.
Journal of pharmacological and toxicological methods
Burgoyne JR,Oviosu O,Eaton P
PA1-913 was used in western blot to develop an assay utilizing a PEG-based alkylating agent for the semi-quantitative measurement of the reversible oxidation of protein cysteine residues
Mon Sep 08 00:00:00 EDT 2014
Comparative differential proteomic profiles of nonfailing and failing hearts after in vivo thoracic aortic constriction in mice overexpressing FKBP12.6.
Physiological reports
Prévilon M,Le Gall M,Chafey P,Federeci C,Pezet M,Clary G,Broussard C,François G,Mercadier JJ,Rouet-Benzineb P
PA1-913 was used in western blot to study the proteomic profiles of failing and non-failing hearts of FKBP12.6-overexpressing mice subjected to thoracic aortic constriction
Thu Aug 01 00:00:00 EDT 2013
Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction.
Circulation
Gurha P,Abreu-Goodger C,Wang T,Ramirez MO,Drumond AL,van Dongen S,Chen Y,Bartonicek N,Enright AJ,Lee B,Kelm RJ,Reddy AK,Taffet GE,Bradley A,Wehrens XH,Entman ML,Rodriguez A
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue Jun 05 00:00:00 EDT 2012
Functional evidence for an active role of B-type natriuretic peptide in cardiac remodelling and pro-arrhythmogenicity.
Cardiovascular research
Thireau J,Karam S,Fauconnier J,Roberge S,Cassan C,Cazorla O,Aimond F,Lacampagne A,Babuty D,Richard S
PA1-913 was used in western blot to study the role of B-type natriuretic peptide in cardiac remodelling and pro-arrhythmogenicity
Sun Jul 01 00:00:00 EDT 2012
Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy.
The Journal of cell biology
Drawnel FM,Wachten D,Molkentin JD,Maillet M,Aronsen JM,Swift F,Sjaastad I,Liu N,Catalucci D,Mikoshiba K,Hisatsune C,Okkenhaug H,Andrews SR,Bootman MD,Roderick HL
PA1-913 was used in western blot to study the role of inositol-1,4,5-triphosphate receptor II and muscle-specific miRNA-133a in pro-hypertrophic calcium metabolism in heart
Mon Nov 26 00:00:00 EST 2012
Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Sassi Y,Abi-Gerges A,Fauconnier J,Mougenot N,Reiken S,Haghighi K,Kranias EG,Marks AR,Lacampagne A,Engelhardt S,Hatem SN,Lompre AM,Hulot JS
PA1-913 was used in western blot to study the role of efflux protein MRP4 in cAMP homeostasis in cardiac myocytes
Thu Mar 01 00:00:00 EST 2012
Functional scaffold-free 3-D cardiac microtissues: a novel model for the investigation of heart cells.
American journal of physiology. Heart and circulatory physiology
Desroches BR,Zhang P,Choi BR,King ME,Maldonado AE,Li W,Rago A,Liu G,Nath N,Hartmann KM,Yang B,Koren G,Morgan JR,Mende U
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue May 15 00:00:00 EDT 2012
CREB critically regulates action potential shape and duration in the adult mouse ventricle.
American journal of physiology. Heart and circulatory physiology
Schulte JS,Seidl MD,Nunes F,Freese C,Schneider M,Schmitz W,Müller FU
PA1-913 was used in western blot to study the role of CREB in action potential regulation in the adult mouse ventricle
Tue May 15 00:00:00 EDT 2012
Immortalization of bone marrow-derived porcine mesenchymal stem cells and their differentiation into cells expressing cardiac phenotypic markers.
Journal of tissue engineering and regenerative medicine
Moscoso I,Rodriguez-Barbosa JI,Barallobre-Barreiro J,Anon P,Domenech N
PA1-913 was used in western blot to immortalize bone marrow-derived porcine mesenchymal stem cells
Wed Aug 01 00:00:00 EDT 2012
Role of Junctin protein interactions in cellular dynamics of calsequestrin polymer upon calcium perturbation.
The Journal of biological chemistry
Lee KW,Maeng JS,Choi JY,Lee YR,Hwang CY,Park SS,Park HK,Chung BH,Lee SG,Kim YS,Jeon H,Eom SH,Kang C,Kim DH,Kwon KS
PA1-913 was used in immunoprecipitation to investigate the role of junctin in calsequestrin polymerization and depolymerization and in calcium homeostasis
Fri Jan 13 00:00:00 EST 2012
Conserved expression and functions of PDE4 in rodent and human heart.
Basic research in cardiology
Richter W,Xie M,Scheitrum C,Krall J,Movsesian MA,Conti M
PA1-913 was used in western blot to investigate the distribution and function of PDE4 in mammalian heart
Tue Mar 01 00:00:00 EST 2011
Ageing, but not yet senescent, rats exhibit reduced muscle quality and sarcoplasmic reticulum function.
Acta physiologica (Oxford, England)
Russ DW,Grandy JS,Toma K,Ward CW
PA1-913 was used in western blot to study the effects of ageing on muscle quality and sarcoplasmic reticulum Ca(2+) release.
Tue Mar 01 00:00:00 EST 2011
Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure.
The Journal of physiology
Briston SJ,Caldwell JL,Horn MA,Clarke JD,Richards MA,Greensmith DJ,Graham HK,Hall MC,Eisner DA,Dibb KM,Trafford AW
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Tue Mar 15 00:00:00 EDT 2011
SR-targeted CaMKII inhibition improves SR Ca²+ handling, but accelerates cardiac remodeling in mice overexpressing CaMKIIδC.
Journal of molecular and cellular cardiology
Huke S,Desantiago J,Kaetzel MA,Mishra S,Brown JH,Dedman JR,Bers DM
PA1-913 was used in western blot to study the role of CaMKII inhibition in calcium homeostasis and cardiac hypertrophy
Sat Jan 01 00:00:00 EST 2011
Couplons in rat atria form distinct subgroups defined by their molecular partners.
Journal of cell science
Schulson MN,Scriven DR,Fletcher P,Moore ED
PA1-913 was used in immunohistochemistry to investigate the localization and function of RyR2 in atria cells
Fri Apr 01 00:00:00 EDT 2011
Knockout of the Na,K-ATPase α₂-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension.
American journal of physiology. Heart and circulatory physiology
Rindler TN,Dostanic I,Lasko VM,Nieman ML,Neumann JC,Lorenz JN,Lingrel JB
PA1-913 was used in western blot to investigate the role of sodium/potassium ATPase alpha2 isoform in blood pressure maintenance
Sat Oct 01 00:00:00 EDT 2011
Antioxidant network expression abrogates oxidative posttranslational modifications in mice.
American journal of physiology. Heart and circulatory physiology
Mital R,Zhang W,Cai M,Huttinger ZM,Goodman LA,Wheeler DG,Ziolo MT,Dwyer KM,d'Apice AJ,Zweier JL,He G,Cowan PJ,Gumina RJ
PA1-913 was used in western blot to examine the therapeutic effect of antioxidant enzymes against myocardial ischemia-reperfusion injury
Sun May 01 00:00:00 EDT 2011
Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression.
American journal of physiology. Heart and circulatory physiology
Han P,Cai W,Wang Y,Lam CK,Arvanitis DA,Singh VP,Chen S,Zhang H,Zhang R,Cheng H,Kranias EG
PA1-913 was used in western blot to investigate the relationship between histidine-rich calcium binding protein HRC S96A variant overexpression and human arrhythmias
Sat Oct 01 00:00:00 EDT 2011
STAT subtype specificity and ischemic preconditioning in mice: is STAT-3 enough?
American journal of physiology. Heart and circulatory physiology
Goodman MD,Koch SE,Afzal MR,Butler KL
PA1-913 was used in western blot to investigate the association between STAT subtype and ischemic tolerance
Tue Feb 01 00:00:00 EST 2011
Organic cation transporter 3: expression in failing and nonfailing human heart and functional characterization.
Journal of cardiovascular pharmacology
Solbach TF,Grube M,Fromm MF,Zolk O
PA1-913 was used in western blot to study the expression of organic cation transporter 3 in normal and abnormal hearts
Sat Oct 01 00:00:00 EDT 2011
FKBP12.6 mice display temporal gender differences in cardiac Ca(2+)-signalling phenotype upon chronic pressure overload.
Canadian journal of physiology and pharmacology
Prévilon M,Pezet M,Semprez F,Mercadier JJ,Rouet-Benzineb P
PA1-913 was used in western blot to investigate the role of FKBP12.6 in the cardiac calcium homeostasis and in the pathogenesis of heart failure
Tue Nov 01 00:00:00 EDT 2011
4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues.
PloS one
Baddeley D,Crossman D,Rossberger S,Cheyne JE,Montgomery JM,Jayasinghe ID,Cremer C,Cannell MB,Soeller C
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Immunofluorescence
Wed Oct 05 00:00:00 EDT 2011
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway.
PloS one
Finsen AV,Lunde IG,Sjaastad I,Østli EK,Lyngra M,Jarstadmarken HO,Hasic A,Nygård S,Wilcox-Adelman SA,Goetinck PF,Lyberg T,Skrbic B,Florholmen G,Tønnessen T,Louch WE,Djurovic S,Carlson CR,Christensen G
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Fri Jul 20 00:00:00 EDT 2012
Differential effect of calsequestrin ablation on structure and function of fast and slow skeletal muscle fibers.
Journal of biomedicine & biotechnology
Paolini C,Quarta M,D'Onofrio L,Reggiani C,Protasi F
PA1-913 was used in western blot to investigate the role of calsequestrin in the structure and function of skeletal muscle fibers
Thu Jan 12 00:00:00 EST 2012
Chronic heart rate reduction with ivabradine improves systolic function of the reperfused heart through a dual mechanism involving a direct mechanical effect and a long-term increase in FKBP12/12.6 expression.
European heart journal
Couvreur N,Tissier R,Pons S,Chetboul V,Gouni V,Bruneval P,Mandet C,Pouchelon JL,Berdeaux A,Ghaleh B
PA1-913 was used in western blot to investigate the mechanism of heart rate and blook pressure regulation by ivabradine
Tue Jun 01 00:00:00 EDT 2010
Carbon monoxide pollution promotes cardiac remodeling and ventricular arrhythmia in healthy rats.
American journal of respiratory and critical care medicine
Andre L,Boissière J,Reboul C,Perrier R,Zalvidea S,Meyer G,Thireau J,Tanguy S,Bideaux P,Hayot M,Boucher F,Obert P,Cazorla O,Richard S
PA1-913 was used in western blot to investigate the effect of carbon monoxide on heart function
Mon Mar 15 00:00:00 EDT 2010
Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.
Circulation research
Zhang T,Guo T,Mishra S,Dalton ND,Kranias EG,Peterson KL,Bers DM,Brown JH
PA1-913 was used in western blot to investigate the effect of phospholamban blockade on heart function in transgenic mice
Fri Feb 05 00:00:00 EST 2010
Mitochondrial uncoupling downregulates calsequestrin expression and reduces SR Ca2+ stores in cardiomyocytes.
Cardiovascular research
Hänninen SL,Ronkainen JJ,Leskinen H,Tavi P
PA1-913 was used in western blot to investigate the effect of mitochondrial uncoupling on specific gene expression and calcium signal in heart cells
Fri Oct 01 00:00:00 EDT 2010
Caspase-dependent protein phosphatase 2A activation contributes to endotoxin-induced cardiomyocyte contractile dysfunction.
Critical care medicine
Neviere R,Hassoun SM,Decoster B,Bouazza Y,Montaigne D,Maréchal X,Marciniak C,Marchetti P,Lancel S
PA1-913 was used in western blot to investigate the mechanism of intracellular calcium dysregulation caused by endotoxin
Fri Oct 01 00:00:00 EDT 2010
Postnatal development of mouse heart: formation of energetic microdomains.
The Journal of physiology
Piquereau J,Novotova M,Fortin D,Garnier A,Ventura-Clapier R,Veksler V,Joubert F
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Thu Jul 01 00:00:00 EDT 2010
A new regulation of IL-6 production in adult cardiomyocytes by beta-adrenergic and IL-1 beta receptors and induction of cellular hypertrophy by IL-6 trans-signalling.
Cellular signalling
Szabo-Fresnais N,Lefebvre F,Germain A,Fischmeister R,Pomérance M
PA1-913 was used in western blot to investigate the mechanism of IL6 regulation and cellular hypertrophy in adult heart muslce cells
Thu Jul 01 00:00:00 EDT 2010
Diabetes-related defects in sarcoplasmic Ca2+ release are prevented by inactivation of G(alpha)11 and G(alpha)q in murine cardiomyocytes.
Molecular and cellular biochemistry
Hoyer DP,Grönke S,Frank KF,Addicks K,Wettschureck N,Offermanns S,Erdmann E,Reuter H
PA1-913 was used in western blot to investigate the role of G-protein signaling in diabetes-defective cardiomyocytes
Sun Aug 01 00:00:00 EDT 2010
Superior calcium homeostasis of extraocular muscles.
Experimental eye research
Zeiger U,Mitchell CH,Khurana TS
PA1-913 was used in western blot to investigate the effect of calcium buffering on extraocular muscles
Mon Nov 01 00:00:00 EDT 2010
S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle.
The Biochemical journal
Woo JS,Hwang JH,Ko JK,Weisleder N,Kim DH,Ma J,Lee EH
PA1-913 was used in western blot to investigate the effect of junctophilin 2 mutation on calcium signalling in skeletal muscle
Mon Mar 15 00:00:00 EDT 2010
Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy.
International journal of experimental pathology
Pertille A,de Carvalho CL,Matsumura CY,Neto HS,Marques MJ
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Immunofluorescence
Mon Feb 01 00:00:00 EST 2010
Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy.
International journal of experimental pathology
Pertille A,de Carvalho CL,Matsumura CY,Neto HS,Marques MJ
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Immunofluorescence
Mon Feb 01 00:00:00 EST 2010
Sequential alterations in Akt, GSK3β, and calcineurin signalling in the mouse left ventricle after thoracic aortic constriction.
Canadian journal of physiology and pharmacology
Prévilon M,Pezet M,Dachez C,Mercadier JJ,Rouet-Benzineb P
PA1-913 was used in western blot to investigate the changes of gene expression in left ventricular hypertrophy
Mon Nov 01 00:00:00 EDT 2010
The calsequestrin mutation CASQ2D307H does not affect protein stability and targeting to the junctional sarcoplasmic reticulum but compromises its dynamic regulation of calcium buffering.
The Journal of biological chemistry
Kalyanasundaram A,Bal NC,Franzini-Armstrong C,Knollmann BC,Periasamy M
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Immunohistochemistry
Fri Jan 29 00:00:00 EST 2010
The calsequestrin mutation CASQ2D307H does not affect protein stability and targeting to the junctional sarcoplasmic reticulum but compromises its dynamic regulation of calcium buffering.
The Journal of biological chemistry
Kalyanasundaram A,Bal NC,Franzini-Armstrong C,Knollmann BC,Periasamy M
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Immunohistochemistry
Fri Jan 29 00:00:00 EST 2010
Altered contractility of skeletal muscle in mice deficient in titin's M-band region.
Journal of molecular biology
Ottenheijm CA,Hidalgo C,Rost K,Gotthardt M,Granzier H
PA1-913 was used in western blot to investigate the role of M-band region of titin in muscle contraction
Fri Oct 16 00:00:00 EDT 2009
Effects of AT1- and beta-adrenergic receptor antagonists on TGF-beta1-induced fibrosis in transgenic mice.
European journal of clinical investigation
Seeland U,Schäffer A,Selejan S,Hohl M,Reil JC,Müller P,Rosenkranz S,Böhm M
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Thu Oct 01 00:00:00 EDT 2009
Diltiazem and verapamil protect dystrophin-deficient muscle fibers of MDX mice from degeneration: a potential role in calcium buffering and sarcolemmal stability.
Muscle & nerve
Matsumura CY,Pertille A,Albuquerque TC,Santo Neto H,Marques MJ
PA1-913 was used in western blot to study the novel role of diltiazem and verapamil in calcium homeostasis and sarcolemmal stability
Sun Feb 01 00:00:00 EST 2009
Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model.
Circulation research
Rizzi N,Liu N,Napolitano C,Nori A,Turcato F,Colombi B,Bicciato S,Arcelli D,Spedito A,Scelsi M,Villani L,Esposito G,Boncompagni S,Protasi F,Volpe P,Priori SG
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Immunocytochemistry
Fri Aug 01 00:00:00 EDT 2008
Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction.
Cardiovascular research
Palpant NJ,Day SM,Herron TJ,Converso KL,Metzger JM
PA1-913 was used in western blot to investigate the role of single histidine-substituted troponin I on the protection of cardiac function in aged mice
Sat Nov 01 00:00:00 EDT 2008
Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo.
American journal of physiology. Heart and circulatory physiology
O'Donnell JM,Fields A,Xu X,Chowdhury SA,Geenen DL,Bi J
PA1-913 was used in western blot to study the results of adenoviral SERCA1 gene transfer in Sprague-Dawley rat hearts.
Mon Dec 01 00:00:00 EST 2008
Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active G alpha o* protein.
American journal of physiology. Heart and circulatory physiology
Zhu M,Gach AA,Liu G,Xu X,Lim CC,Zhang JX,Mao L,Chuprun K,Koch WJ,Liao R,Koren G,Blaxall BC,Mende U
PA1-913 was used in western blot to investigate the role of G alpha o on calcium cycling and contractile function in heart
Sat Mar 01 00:00:00 EST 2008
Cardiac-directed parvalbumin transgene expression in mice shows marked heart rate dependence of delayed Ca2+ buffering action.
Physiological genomics
Day SM,Coutu P,Wang W,Herron T,Turner I,Shillingford M,Lacross NC,Converso KL,Piao L,Li J,Lopatin AN,Metzger JM
PA1-913 was used in western blot to investigate the role of parvalbumin in calcium homeostasis and heart failure
Tue May 13 00:00:00 EDT 2008
Reduced expression of sarcalumenin and related Ca2+ -regulatory proteins in aged rat skeletal muscle.
Experimental gerontology
O'Connell K,Gannon J,Doran P,Ohlendieck K
PA1-913 was used in western blot to investigate the expression of sarcalumenin and related calcium-regulatory proteins in rodent skeletal muscle during aging
Wed Oct 01 00:00:00 EDT 2008
S100A1 deficiency results in prolonged ventricular repolarization in response to sympathetic activation.
General physiology and biophysics
Ackermann GE,Domenighetti AA,Deten A,Bonath I,Marenholz I,Pedrazzini T,Erne P,Heizmann CW
PA1-913 was used in western blot to investigate the role of S100A1 in normal heart function
Sun Jun 01 00:00:00 EDT 2008
Interstitial remodeling in beta1-adrenergic receptor transgenic mice.
Basic research in cardiology
Seeland U,Selejan S,Engelhardt S,Müller P,Lohse MJ,Böhm M
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Thu Mar 01 00:00:00 EST 2007
Disruption of the intracellular Ca2+ homeostasis in the cardiac excitation-contraction coupling is a crucial mechanism of arrhythmic toxicity in aconitine-induced cardiomyocytes.
Biochemical and biophysical research communications
Fu M,Wu M,Wang JF,Qiao YJ,Wang Z
PA1-913 was used in western blot to investigate the mechanism of arrhythmic cytotoxicity in heart cells treated with aconitine
Fri Mar 23 00:00:00 EDT 2007
Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia.
Circulation
di Barletta MR,Viatchenko-Karpinski S,Nori A,Memmi M,Terentyev D,Turcato F,Valle G,Rizzi N,Napolitano C,Gyorke S,Volpe P,Priori SG
PA1-913 was used in western blot to investigate the clinical phenotype and function of cardiac calsequestrin gene (CASQ2) mutations linked to catecholaminergic polymorphic ventricular tachycardia
Tue Sep 05 00:00:00 EDT 2006
High intracellular Na+ preserves myocardial function at low heart rates in isolated myocardium from failing hearts.
European journal of heart failure
Schillinger W,Teucher N,Christians C,Kohlhaas M,Sossalla S,Van Nguyen P,Schmidt AG,Schunck O,Nebendahl K,Maier LS,Zeitz O,Hasenfuss G
PA1-913 was used in western blot to study the relationship between the intracellular sodium concentrate and myocardial function
Wed Nov 01 00:00:00 EST 2006
Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy.
Cardiovascular research
Custodis F,Eberl M,Kilter H,Böhm M,Laufs U
PA1-913 was used in western blot to study the role of RhoGDIalpha and Rac1 GTPase in free radical production during myocardial hypertrophy
Sat Jul 15 00:00:00 EDT 2006
LAMP-2 deficient mice show depressed cardiac contractile function without significant changes in calcium handling.
Basic research in cardiology
Stypmann J,Janssen PM,Prestle J,Engelen MA,Kögler H,Lüllmann-Rauch R,Eckardt L,von Figura K,Landgrebe J,Mleczko A,Saftig P
PA1-913 was used in western blot to investigate the effect of LAMP-2 on cardiac contractile function and its mechanism
Sat Jul 01 00:00:00 EDT 2006
Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction.
Stem cells (Dayton, Ohio)
Dolnikov K,Shilkrut M,Zeevi-Levin N,Gerecht-Nir S,Amit M,Danon A,Itskovitz-Eldor J,Binah O
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Wed Feb 01 00:00:00 EST 2006
Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein.
Molecular and cellular biology
Jaehnig EJ,Heidt AB,Greene SB,Cornelissen I,Black BL
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Fri Dec 01 00:00:00 EST 2006
Triadin overexpression stimulates excitation-contraction coupling and increases predisposition to cellular arrhythmia in cardiac myocytes.
Circulation research
Terentyev D,Cala SE,Houle TD,Viatchenko-Karpinski S,Gyorke I,Terentyeva R,Williams SC,Gyorke S
PA1-913 was used in western blot to study the functional properties of TRD in myocardial intracellular Ca handling
Fri Apr 01 00:00:00 EST 2005
Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies.
Human molecular genetics
Arimura T,Helbling-Leclerc A,Massart C,Varnous S,Niel F,Lacène E,Fromes Y,Toussaint M,Mura AM,Keller DI,Amthor H,Isnard R,Malissen M,Schwartz K,Bonne G
PA1-913 was used in western blot to develop a mouse model for laminopathies.
Sat Jan 01 00:00:00 EST 2005
Differential activation of stress-response signaling in load-induced cardiac hypertrophy and failure.
Physiological genomics
Rothermel BA,Berenji K,Tannous P,Kutschke W,Dey A,Nolan B,Yoo KD,Demetroulis E,Gimbel M,Cabuay B,Karimi M,Hill JA
Published figure using Calsequestrin polyclonal antibody (Product # PA1-913) in Western Blot
Wed Sep 21 00:00:00 EDT 2005
Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum.
The Journal of biological chemistry
Kaliman P,Catalucci D,Lam JT,Kondo R,Gutiérrez JC,Reddy S,Palacín M,Zorzano A,Chien KR,Ruiz-Lozano P
PA1-913 was used in western blot to examine the DMPK pathway and to try to find the molecular mechansim for DM heart pathology
Fri Mar 04 00:00:00 EST 2005
Abnormal calcium signaling and sudden cardiac death associated with mutation of calsequestrin.
Circulation research
Viatchenko-Karpinski S,Terentyev D,Györke I,Terentyeva R,Volpe P,Priori SG,Napolitano C,Nori A,Williams SC,Györke S
PA1-913 was used in western blot to investigate the relationship between CASQ2D307H's expression and the clinical phenotype seen in patients with this mutation
Fri Mar 05 00:00:00 EST 2004
Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model.
Cardiovascular research
Janczewski AM,Zahid M,Lemster BH,Frye CS,Gibson G,Higuchi Y,Kranias EG,Feldman AM,McTiernan CF
PA1-913 was used in western blot to study the effect of the phospholamban gene ablation on calcium transient and cardiac function
Tue Jun 01 00:00:00 EDT 2004
Phosphorylation-status of phospholamban and calsequestrin modifies their affinity towards commonly used antibodies.
Journal of molecular and cellular cardiology
Huke S,Periasamy M
PA1-913 was used in western blot to investigate the influence of phosphorylation on specific protein interaction with their cognate antibodies
Wed Sep 01 00:00:00 EDT 2004
Human homozygous R403W mutant cardiac myosin presents disproportionate enhancement of mechanical and enzymatic properties.
Journal of molecular and cellular cardiology
Keller DI,Coirault C,Rau T,Cheav T,Weyand M,Amann K,Lecarpentier Y,Richard P,Eschenhagen T,Carrier L
PA1-913 was used in western blot to investigate the effect of homozygous R403W mutant cardiac myosin on mechanical and enzymatic properties of myocardium
Mon Mar 01 00:00:00 EST 2004
Regulation of dihydropyridine receptor gene expression in mouse skeletal muscles by stretch and disuse.
American journal of physiology. Cell physiology
Radzyukevich TL,Heiny JA
PA1-913 was used in western blot to study the change of DHPR's gene expression in mouse skeletal muscles during physiological adaptations to disuse
Mon Nov 01 00:00:00 EST 2004
The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.
American journal of physiology. Cell physiology
Radzyukevich TL,Moseley AE,Shelly DA,Redden GA,Behbehani MM,Lingrel JB,Paul RJ,Heiny JA
PA1-913 was used in western blot to study the role of the sodium/potassium-ATPase alpha2-subunit isoform during muscle contraction
Mon Nov 01 00:00:00 EST 2004
Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity.
American journal of physiology. Heart and circulatory physiology
Schultz Jel J,Glascock BJ,Witt SA,Nieman ML,Nattamai KJ,Liu LH,Lorenz JN,Shull GE,Kimball TR,Periasamy M
PA1-913 was used in western blot to investigate the effect of chronically decreased SERCA2 calcium pump activity on heart failure in mice
Mon Mar 01 00:00:00 EST 2004
Effects of chronic endothelin-1 stimulation on cardiac myocyte contractile function.
American journal of physiology. Heart and circulatory physiology
Zolk O,Münzel F,Eschenhagen T
PA1-913 was used in western blot to investigate the effects of chronic endothelin-1 (ET-1) stimulation on the contractile function of cardiac myocyte
Thu Apr 01 00:00:00 EST 2004
Mechanical load-dependent regulation of gene expression in monocrotaline-induced right ventricular hypertrophy in the rat.
Circulation research
Kögler H,Hartmann O,Leineweber K,Nguyen van P,Schott P,Brodde OE,Hasenfuss G
PA1-913 was used in western blot to investigate the effects of increased mechanical load on the regulation of gene expression in the myocardium
Fri Aug 08 00:00:00 EDT 2003
Na(+)-Ca(2+) exchanger overexpression predisposes to reactive oxygen species-induced injury.
Cardiovascular research
Wagner S,Seidler T,Picht E,Maier LS,Kazanski V,Teucher N,Schillinger W,Pieske B,Isenberg G,Hasenfuss G,Kögler H
PA1-913 was used in western blot to demonstrate that the overexpression of sodium/calcium exchanger is more susceptible to reactive oxygen species (ROS)-induced injury
Sat Nov 01 00:00:00 EST 2003
Gender differences in sarcoplasmic reticulum calcium loading after isoproterenol.
American journal of physiology. Heart and circulatory physiology
Chen J,Petranka J,Yamamura K,London RE,Steenbergen C,Murphy E
PA1-913 was used in western blot to study the possible relationship between SR calcium loading after isoproterenol and gender as well as its correlation with gender differences in ischemia-reperfusion injury
Mon Dec 01 00:00:00 EST 2003
Targeted inhibition of Ca2+/calmodulin-dependent protein kinase II in cardiac longitudinal sarcoplasmic reticulum results in decreased phospholamban phosphorylation at threonine 17.
The Journal of biological chemistry
Ji Y,Li B,Reed TD,Lorenz JN,Kaetzel MA,Dedman JR
PA1-913 was used in western blot to investigate the role of the calcium/calmodulin-dependent kinase II pathway in cardiac disease.
Fri Jul 04 00:00:00 EDT 2003
Augmented expression of cardiotrophin-1 in failing human hearts is accompanied by diminished glycoprotein 130 receptor protein abundance.
Circulation
Zolk O,Ng LL,O'Brien RJ,Weyand M,Eschenhagen T
PA1-913 was used in western blot to investigate the role of gp130 receptor downregulation for CT-1 expression and the gp130 signaling pathway regulation in failing human hearts
Tue Sep 17 00:00:00 EDT 2002
A novel and rapid approach to isolating functional ryanodine receptors.
Biochemical and biophysical research communications
West DJ,Smith EC,Williams AJ
PA1-913 was used in western blot to develop a method for the rapid isolation of ryanodine receptors in a functional state
Fri Jun 07 00:00:00 EDT 2002
Supramolecular calsequestrin complex.
European journal of biochemistry
Glover L,Quinn S,Ryan M,Pette D,Ohlendieck K
PA1-913 was used in western blot to investigate the formation of supramolecular calsequestrin complex
Sun Sep 01 00:00:00 EDT 2002
Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality.
Circulation
Dash R,Kadambi V,Schmidt AG,Tepe NM,Biniakiewicz D,Gerst MJ,Canning AM,Abraham WT,Hoit BD,Liggett SB,Lorenz JN,Dorn GW,Kranias EG
PA1-913 was used in western blot to investigate the role of phospholamban (PLB) in the development of cardiomyopathy and early mortality
Tue Feb 13 00:00:00 EST 2001
Identification of triadin 1 as the predominant triadin isoform expressed in mammalian myocardium.
The Journal of biological chemistry
Kobayashi YM,Jones LR
PA1-913 was used in western blot to study the expression of triadin isoform in mammalian cardiac muscle
Fri Oct 01 00:00:00 EDT 1999
Developmental changes in cardiac sarcoplasmic reticulum in sheep.
The Journal of biological chemistry
Mahony L,Jones LR
PA1-913 was used in western blot to investigate the protein components of cardiac sarcoplasmic reticulum vesicles and corresponding changes of functions during sheep development
Sat Nov 15 00:00:00 EST 1986
