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Product Details
MA5-18318
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6B4
Immunogen
Synthetic peptide corresponding to amino acids C-terminus of human Calumenin
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2539685
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 45 kDa, although the predicted MW is 37 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and/or wound healing by acting in an autocrine or paracrine manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calumenin; Crocalbin; crocalbin-like protein; IEF SSP 9302; multiple EF-hand protein
Gene Aliases: 9530075H20Rik; CALU
UniProt ID: (Human) Q96RL3, (Mouse) O35887
Entrez Gene ID: (Human) 813, (Mouse) 12321
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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