Proteintech

Cannabinoid receptor 1 Polyclonal Antibody

Cannabinoid receptor 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 6

Cannabinoid receptor 1 Antibody (17978-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 17978-1-AP ( Cannabinoid receptor 1 antibody at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Cannabinoid receptor 1 Antibody in Western Blot (WB)

Cannabinoid receptor 1 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

17978-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Cannabinoid receptor 1 Fusion Protein Ag12371 (1-121 aa encoded by BC074812)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MKSILDGLA DTTFRTITTD LLYVGSNDIQ YEDIKGDMAS KLGYFPQKFP LTSFRGSPFQ EKMTAGDNPQ LVPADQVNIT EFYNKSLSSF KENEENIQCG ENFMDIECFM VLNPSQQLAI AV (1-121 aa encoded by BC074812)

Target Information

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Electroacupuncture repairs intestinal barrier by upregulating CB1 through gut microbiota in DSS-induced acute colitis.

Chinese medicine

Yang J,Wang L,Mei M,Guo J,Yang X,Liu S

Fri Mar 10 00:00:00 EST 2023

Reward enhances resilience to chronic social defeat stress in mice: Neural ECs and mGluR5 mechanism via neuroprotection in VTA and DRN.

Frontiers in psychiatry

Shi P,Hu L,Ren H,Dai Q

Tue Mar 07 00:00:00 EST 2023

Cisplatin-Induced Anorexia and Pica Behavior in Rats Enhanced by Chronic Stress Pretreatment.

Frontiers in pharmacology

Guo Z,Duan J,Chen Y,Cai W,Yang C,Yang Z,Liu X,Xu F

Tue Aug 02 00:00:00 EDT 2022

Endocannabinoid signalling/cannabinoid receptor 2 is involved in icariin-mediated protective effects against bleomycin-induced pulmonary fibrosis.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Du W,Zhang T,Yang F,Gul A,Tang Z,Zhang H,Jiang S,Wang S,Dong J

Mon Aug 01 00:00:00 EDT 2022

L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1.

Food & function

Liu A,Lin L,Xu W,Gong Z,Liu Z,Xiao W

Mon Jul 05 00:00:00 EDT 2021

Cardiac sudden death in a young cannabis user.

Legal medicine (Tokyo, Japan)

Kasuda S,Kondo T,Terazawa I,Morimoto M,Yuui K,Kudo R

Mon Nov 01 00:00:00 EDT 2021

A combination of dietary fat intake and nicotine exposure enhances CB1 endocannabinoid receptor expression in hypothalamic nuclei in male mice.

Neuroscience letters

Guo T,Tanaka T,Matsumoto M,Kaneko K,Unzai T,Ogino Y,Aotani D,Kusakabe T,Iwakura H,Miyazawa T,Sawamoto K,Minokoshi Y,Masuzaki H,Inagaki N,Nakao K

Wed Jan 01 00:00:00 EST 2020

Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression-like behaviour via cannabinoid system in sleep deprivation rats.

Behavioural brain research

Wang T,Niu K,Fan A,Bi N,Tao H,Chen XT,Wang HL

Mon Apr 20 00:00:00 EDT 2020

N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.

International journal of molecular medicine

Liu X,Wu Y,Zhou D,Xie Y,Zhou Y,Lu Y,Yang R,Liu S

Sun Nov 01 00:00:00 EDT 2020

Trans-cinnamaldehyde shows anti-depression effect in the forced swimming test and possible involvement of the endocannabinoid system.

Biochemical and biophysical research communications

Lin J,Song Z,Chen X,Zhao R,Chen J,Chen H,Yang X,Wu Z

Tue Oct 15 00:00:00 EDT 2019

Indoxyl sulfate upregulates the cannabinoid type 1 receptor gene via an ATF3/c-Jun complex-mediated signaling pathway in the model of uremic cardiomyopathy.