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Invitrogen
Carbonic Anhydrase VIII Polyclonal Antibody
FIGURE: 1 / 2
Carbonic Anhydrase VIII Antibody (PA5-47267) in WB
Western blot analysis of Carbonic Anhydrase VIII in 0.2 mg/mL lysates of human brain (cerebellum) tissue and mouse brain (cerebellum) tissue. Samples were incubated in Carbonic Anhydrase VIII polyclonal antibody (Product # PA5-47267) using a dilution of 5 µg/mL followed by HRP-conjugated Anti-Goat IgG at a dilution of 1:50. Specific bands were detected for Carbonic Anhydrase VIII/CA8 at approximately 41 and... View More
Product Details
PA5-47267
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human Carbonic AnhydraseVIII/CA8 Ala2-Gln290
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608925
Product Specific Information
In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) CA2 and rhCA3 is observed and less than 1% cross-reactivity with rhCA1, rhCA4, and rhCA9 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA-related protein; CA-RP VIII; CA-VIII; carbonate dehydratase; Carbonic anhydrase VIII; carbonic anhydrase-like sequence; carbonic anhydrase-like sequence 1; Carbonic anhydrase-related protein; CARP; MGC120502; MGC99509
Gene Aliases: AW546993; CA-RP; CA-VIII; CA8; CALS; Cals1; CAMRQ3; Car8; CARP; wdl
UniProt ID: (Human) P35219, (Mouse) P28651
Entrez Gene ID: (Human) 767, (Mouse) 12319
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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