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Caspase 6 Antibody (MA5-41562) in IHC (P)
Immunohistochemistry analysis of Caspase 6 in paraffin-embedded Bovine Small intestine tissue. Samples were incubated with monoclonal antibody (Product # MA5-41562) at a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 2 µg/mL.
Product Details
MA5-41562
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine
Host/Isotype
Mouse
/ IgG, kappa
Class
Monoclonal
Type
Antibody
Clone
C1
Immunogen
Recombinant protein Caspase 6
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899044
Target Information
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CASP-6; caspase 6, apoptosis-related cysteine peptidase; Caspase-6; mCASP-6
Gene Aliases: CASP6
UniProt ID: (Bovine) Q3T0P5
Entrez Gene ID: (Bovine) 538409
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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