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Product Details
PA5-78923
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of rat Caspase-6 (P18) (7-27aa FYRSREVLDPAEQYKMDHKRR).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746039
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Caspase 6 is an enzyme that in humans is encoded by the caspase 6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Using radiation hybrid mapping, the Caspase 6 gene is localized to human chromosome 4q25-q26. Caspase 6 functions as a downstream enzyme in the caspase activation cascade. And Caspase 6 can cleave lamin A to its signature apoptotic fragment.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptotic protease Mch-2; CASP-6; Caspase-6
Gene Aliases: CASP-6; Casp6; Mch2
UniProt ID: (Mouse) O08738
Entrez Gene ID: (Mouse) 12368, (Rat) 83584
lens development in camera-type eye
acute inflammatory response to non-antigenic stimulus
proteolysis
apoptotic process
response to heat
response to glucose
response to organic substance
response to metal ion
response to iron ion
response to organonitrogen compound
response to gamma radiation
epithelial cell differentiation
response to estradiol
response to testosterone
response to cytokine
response to hydrogen peroxide
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of retinal cell programmed cell death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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