Product References
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Phytotherapy research : PTR
Zhang L,Zhang X,Che D,Zeng L,Zhang Y,Nan K,Zhang X,Zhang H,Guo Z
Sun Jan 01 00:00:00 EST 2023
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Translational stroke research
Lu D,Liu Y,Huang H,Hu M,Li T,Wang S,Shen S,Wu R,Cai W,Lu T,Lu Z
Fri Dec 01 00:00:00 EST 2023
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Translational stroke research
Lu D,Liu Y,Huang H,Hu M,Li T,Wang S,Shen S,Wu R,Cai W,Lu T,Lu Z
Fri Dec 01 00:00:00 EST 2023
Ionizing Radiation Triggers the Antitumor Immunity by Inducing Gasdermin E-Mediated Pyroptosis in Tumor Cells.
International journal of radiation oncology, biology, physics
Cao W,Chen G,Wu L,Yu KN,Sun M,Yang M,Jiang Y,Jiang Y,Xu Y,Peng S,Han W
Wed Feb 01 00:00:00 EST 2023
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Acta pharmacologica Sinica
Liang JP,He YM,Cui YL,Sun YN,He GS,Zhu ZG,Mao XL
Sat Jul 01 00:00:00 EDT 2023
Towards Developing Novel Prostate Cancer Recurrence Suppressors: Acute Toxicity of Pseurotin A, an Orally Active PCSK9 Axis-Targeting Small-Molecule in Swiss Albino Mice.
Molecules (Basel, Switzerland)
McGehee OC,Ebrahim HY,Rad AH,Abdelwahed KS,Mudhish EA,King JA,Helal IE,Meyer SA,El Sayed KA
Thu Feb 02 00:00:00 EST 2023
A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Theranostics
Guo Q,Xin M,Lu Q,Feng D,Yang V,Peng LF,Whelan KA,Hu W,Wu S,Yang X,Wang H,Rothberg BS,Gamero AM,Gerhard GS,Gao B,Yang L
Wed May 10 00:00:00 EDT 2023
GSDMD knockdown exacerbates hippocampal damage and seizure susceptibility by crosstalk between pyroptosis and apoptosis in kainic acid-induced temporal lobe epilepsy.
Biochimica et biophysica acta. Molecular basis of disease
Lin A,Guo Y,Zhang H,Lin P,Tao K,Jiang L,Xu D,Chen B
Thu Jun 01 00:00:00 EDT 2023
METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.
Cell death & disease
Sun K,Chen L,Li Y,Huang B,Yan Q,Wu C,Lai Q,Fang Y,Cai J,Liu Y,Chen J,Wang X,Zhu Y,Dong S,Tan J,Li A,Liu S,Zhang Y
Tue Feb 21 00:00:00 EST 2023
RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis.
Cellular oncology (Dordrecht)
Yao H,Zhang S,Xie H,Fan Y,Miao M,Zhu R,Yuan L,Gu M,You Y,You B
Tue Aug 01 00:00:00 EDT 2023
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Nature communications
Hu M,Li T,Ma X,Liu S,Li C,Huang Z,Lin Y,Wu R,Wang S,Lu D,Lu T,Men X,Shen S,Huang H,Liu Y,Song K,Jian B,Jiang Y,Qiu W,Liu Q,Lu Z,Cai W
Tue Jul 04 00:00:00 EDT 2023
Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis.
Phytochemistry
Liu Y,Liu MY,Bi LL,Tian YY,Qiu PC,Qian XY,Wang MC,Tang HF,Lu YY,Zhang BL
Wed Mar 01 00:00:00 EST 2023
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
Toxicology and applied pharmacology
Fu NJ,Xi RY,Shi XK,Li RZ,Zhang ZH,Li LY,Zhang GL,Wang F
Fri Apr 15 00:00:00 EDT 2022
Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-AThr288-geminin dual signaling pathways.
Frontiers in pharmacology
Zhao H,Jia P,Nanding K,Wu M,Bai X,Morigen M,Fan L
Wed Jan 11 00:00:00 EST 2023
The expression profile of lung long non-coding RNAs and mRNAs in a mouse model of smoke inhalation injury.
Bioengineered
Jiang ZY,Liu MZ,Fu ZH,Liao XC,Xu B,Shi LL,Li JQ,Guo GH
Tue Mar 01 00:00:00 EST 2022
Aberrant Expression of BUB1B Contributes to the Progression of Thyroid Carcinoma and Predicts Poor Outcomes for Patients.
Journal of Cancer
Yan HC,Xiang C
Sat Jul 16 00:00:00 EDT 2022
Ubiquitin conjugating enzyme E2 C (UBE2C) may play a dual role involved in the progression of thyroid carcinoma.
Cell death discovery
Xiang C,Yan HC
Thu Mar 24 00:00:00 EDT 2022
chi-miR-99b-3p Regulates the Proliferation of Goat Skeletal Muscle Satellite Cells In Vitro by Targeting Caspase-3 and NCOR1.
Animals : an open access journal from MDPI
Liao R,Lv Y,Dai J,Zhang D,Zhu L,Lin Y
Sun Sep 11 00:00:00 EDT 2022
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Frontiers in cell and developmental biology
Li W,Wang X,Liu T,Zhang Q,Cao J,Jiang Y,Sun Q,Li C,Wang W,Wang Y
Tue Mar 01 00:00:00 EST 2022
Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.
Cell death discovery
Han Z,Liu M,Xie Y,Zeng K,Zhan Z,Chen Y,Wang L,Chen X,Luo Y,Zeng Y,Zhan H,Lin Y,Zhang K,Zhu X,Liu S,Luo X,Zhou A
Fri Nov 04 00:00:00 EDT 2022
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.
Cancer cell international
Tong Q,Yi M,Kong P,Xu L,Huang W,Niu Y,Gan X,Zhan H,Tian R,Yan D
Tue Sep 06 00:00:00 EDT 2022
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
The American journal of Chinese medicine
Huang ZW,Tan P,Yi XK,Chen H,Sun B,Shi H,Mou ZQ,Cheng YL,Li TX,Li Q,Fu WG
Fri Nov 25 00:00:00 EST 2022
Psychosocial and behavioral problems of children and adolescents in the early stage of reopening schools after the COVID-19 pandemic: a national cross-sectional study in China.
Translational psychiatry
Wang L,Zhang Y,Chen L,Wang J,Jia F,Li F,Froehlich TE,Hou Y,Hao Y,Shi Y,Deng H,Zhang J,Huang L,Xie X,Fang S,Xu L,Xu Q,Guan H,Wang W,Shen J,Qian Y,Wang X,Shan L,Tan C,Yu Y,Wang X,Chen F,Zhang L,Li X,Shi X,Ke X,Li T
Thu Jun 03 00:00:00 EDT 2021
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
Frontiers in oncology
Wen D,Liu WL,Lu ZW,Cao YM,Ji QH,Wei WJ
Sun May 23 00:00:00 EDT 2021
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy.
Drug delivery
Song M,Xia W,Tao Z,Zhu B,Zhang W,Liu C,Chen S
Wed Dec 01 00:00:00 EST 2021
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy.
Drug delivery
Song M,Xia W,Tao Z,Zhu B,Zhang W,Liu C,Chen S
Wed Dec 01 00:00:00 EST 2021
GPR12 inhibits migration and promotes apoptosis in esophageal cancer and hypopharyngeal cancer cells.
Thoracic cancer
Zhang M,Yang X,Chen S,Jia W,Ma X,Wang J,Qian Y,Lei D,Liu H,Pan X
Sat May 01 00:00:00 EDT 2021
ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.
International journal of biological sciences
Zhang H,Xia P,Liu J,Chen Z,Ma W,Yuan Y
Mon Dec 20 00:00:00 EST 2021
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Frontiers in pharmacology
Yang M,Li WY,Xie J,Wang ZL,Wen YL,Zhao CC,Tao L,Li LF,Tian Y,Sheng J
Sat May 08 00:00:00 EDT 2021
3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.
Life sciences
Zhang L,Zheng Y,Zeng L,Zhang F,Che D,Cao Z,Huang C,Xian L,Zhang X,Zhang H,Guo Z
Mon Nov 15 00:00:00 EST 2021
Bismuth Porphyrin Antagonizes Cisplatin-Induced Nephrotoxicity via Unexpected Metallothionein-Independent Mechanisms.
iScience
Wang R,Wang S,Chan S,Wang Y,Zhang Y,Zuo Z,Chi-Fung Chan G,Li H,Sun H
Fri May 22 00:00:00 EDT 2020
A novel antisense lncRNA NT5E promotes progression by modulating the expression of SYNCRIP and predicts a poor prognosis in pancreatic cancer.
Journal of cellular and molecular medicine
Zhang P,Cao M,Zhang Y,Xu L,Meng F,Wu X,Xia T,Chen Q,Shi G,Wu P,Chen L,Lu Z,Yin J,Cai B,Cao S,Miao Y,Jiang K
Tue Sep 01 00:00:00 EDT 2020
Camellia oil (Camellia oleifera Abel.) attenuates CCl4-induced liver fibrosis via suppressing hepatocyte apoptosis in mice.
Food & function
Lei X,Liu Q,Liu Q,Cao Z,Zhang J,Kuang T,Fang Y,Liu G,Qian K,Fu J,Du H,Liu Z,Xiao Z,Li C,Xu X
Fri May 01 00:00:00 EDT 2020
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
Evidence-based complementary and alternative medicine : eCAM
Deng LH,Li L,Zhai Y,Michael S,Yang CY,Guo R,Chen SF,Fan GW,Zhao YQ,Liu W
Tue Nov 03 00:00:00 EST 2020
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Cellular immunology
Gong Z,Kuang Z,Li H,Li C,Ali MK,Huang F,Li P,Li Q,Huang X,Ren S,Li J,Xie J
Tue Jan 01 00:00:00 EST 2019
Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.
Cellular immunology
Gong Z,Kuang Z,Li H,Li C,Ali MK,Huang F,Li P,Li Q,Huang X,Ren S,Li J,Xie J
Tue Jan 01 00:00:00 EST 2019
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Biochemical and biophysical research communications
Zhang Y,Li Q,Yu S,Zhu C,Zhang Z,Cao H,Xu J
Tue Feb 12 00:00:00 EST 2019
Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.
Biochemical and biophysical research communications
Zhang Y,Li Q,Yu S,Zhu C,Zhang Z,Cao H,Xu J
Tue Feb 12 00:00:00 EST 2019
Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis.
OncoTargets and therapy
Xu W,Hu GQ,Da Costa C,Tang JH,Li QR,Du L,Pan YW,Lv SQ
Thu Oct 01 00:00:00 EDT 2020
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Journal of agricultural and food chemistry
Xu H,Li Y,Han B,Li Z,Wang B,Jiang P,Zhang J,Ma W,Zhou D,Li X,Ye X
Wed Sep 19 00:00:00 EDT 2018
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Journal of agricultural and food chemistry
Xu H,Li Y,Han B,Li Z,Wang B,Jiang P,Zhang J,Ma W,Zhou D,Li X,Ye X
Wed Sep 19 00:00:00 EDT 2018
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Wang X,Liu W,Wang P,Li S
Thu Nov 01 00:00:00 EDT 2018
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Wang X,Liu W,Wang P,Li S
Thu Nov 01 00:00:00 EDT 2018
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Chemical research in toxicology
Dong W,Yang B,Wang Y,Yuan J,Fan Y,Song E,Song Y
Mon Nov 19 00:00:00 EST 2018
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
Journal of agricultural and food chemistry
Han B,Jiang P,Liu W,Xu H,Li Y,Li Z,Ma H,Yu Y,Li X,Ye X
Wed Jun 20 00:00:00 EDT 2018
Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.
Journal of pineal research
Gao Y,Xiao X,Zhang C,Yu W,Guo W,Zhang Z,Li Z,Feng X,Hao J,Zhang K,Xiao B,Chen M,Huang W,Xiong S,Wu X,Deng W
Wed Mar 01 00:00:00 EST 2017
Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.
Journal of pineal research
Gao Y,Xiao X,Zhang C,Yu W,Guo W,Zhang Z,Li Z,Feng X,Hao J,Zhang K,Xiao B,Chen M,Huang W,Xiong S,Wu X,Deng W
Wed Mar 01 00:00:00 EST 2017
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Biotechnology and bioengineering
Zhang W,Xiao D,Shan L,Zhao J,Mao Q,Xia H
Wed Nov 01 00:00:00 EDT 2017
Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.
Biotechnology and bioengineering
Zhang W,Xiao D,Shan L,Zhao J,Mao Q,Xia H
Wed Nov 01 00:00:00 EDT 2017
