Product References
Dual targets of lethal apoptosis and protective autophagy in liver cancer with periplocymarin elicit a limited therapeutic effect.
International journal of oncology
Hao Y,Song T,Wang M,Li T,Zhao C,Li T,Hou Y,He H
Wed Mar 01 00:00:00 EST 2023
Evocalcet Rescues Secondary Hyperparathyroidism-driven Cortical Porosity in CKD Male Rats.
Endocrinology
Hasegawa T,Tokunaga S,Yamamoto T,Sakai M,Hongo H,Kawata T,Amizuka N
Sat Feb 11 00:00:00 EST 2023
De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics.
Nature communications
Rowland LA,Guilherme A,Henriques F,DiMarzio C,Munroe S,Wetoska N,Kelly M,Reddig K,Hendricks G,Pan M,Han X,Ilkayeva OR,Newgard CB,Czech MP
Mon Mar 13 00:00:00 EDT 2023
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Cells
Gai C,Zhao Y,Xin D,Li T,Cheng Y,Jiang Z,Song Y,Liu D,Wang Z
Thu Mar 09 00:00:00 EST 2023
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Cells
Gai C,Zhao Y,Xin D,Li T,Cheng Y,Jiang Z,Song Y,Liu D,Wang Z
Thu Mar 09 00:00:00 EST 2023
The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study.
BMC cancer
E Y,Yu Q,Sun T,Xue H,Zhao XR,Zheng HC
Thu Jun 08 00:00:00 EDT 2023
The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study.
BMC cancer
E Y,Yu Q,Sun T,Xue H,Zhao XR,Zheng HC
Thu Jun 08 00:00:00 EDT 2023
Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.
bioRxiv : the preprint server for biology
Zheng W,Chang IC,Limberis J,Budzik JM,Zha BS,Howard Z,Chen L,Ernst JD
Sun May 28 00:00:00 EDT 2023
Cathepsin B mediates the lysosomal-mitochondrial apoptosis pathway in arsenic-induced microglial cell injury.
Human & experimental toxicology
Zhang Z,Pi R,Jiang Y,Ahmad M,Luo H,Luo J,Yang J,Sun B
Wed May 10 00:00:00 EDT 2023
Cathepsin B mediates the lysosomal-mitochondrial apoptosis pathway in arsenic-induced microglial cell injury.
Human & experimental toxicology
Zhang Z,Pi R,Jiang Y,Ahmad M,Luo H,Luo J,Yang J,Sun B
Wed May 10 00:00:00 EDT 2023
The cell type dependent sorting of CD9- and CD81 to extracellular vesicles can be exploited to convey tumor sensitive cargo to target cells.
Drug delivery
Zuppone S,Zarovni N,Vago R
Fri Dec 01 00:00:00 EST 2023
3, 14, 19-Triacetyl Andrographolide alleviates the cognitive dysfunction of 3 × Tg-AD mice by inducing initiation and promoting degradation process of autophagy.
Phytotherapy research : PTR
Zhang H,Xie X,Shi J,Zhao Q,Luo D,Hao J,Zhou Y,Han G,Pang X
Wed Feb 01 00:00:00 EST 2023
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
The Science of the total environment
Pei X,Liu D,Li J,Li L,Ding X,Zhang W,Li Z,Xu G,Li C,Li D
Mon Mar 20 00:00:00 EDT 2023
In addition to its endosomal escape effect, platycodin D also synergizes with ribosomal inactivation protein to induce apoptosis in hepatoma cells through AKT and MAPK signaling pathways.
Chemico-biological interactions
Lei J,Zhao J,Long MY,Cao XW,Wang FJ
Thu Sep 01 00:00:00 EDT 2022
Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis.
Frontiers in immunology
Hu Y,Shi Y,Chen H,Tao M,Zhou X,Li J,Ma X,Wang Y,Liu N
Tue May 03 00:00:00 EDT 2022
Polystyrene micro(nano)plastics damage the organelles of RBL-2H3 cells and promote MOAP-1 to induce apoptosis.
Journal of hazardous materials
Liu L,Liu B,Zhang B,Ye Y,Jiang W
Thu Sep 15 00:00:00 EDT 2022
Methylmercury induces lysosomal membrane permeabilization through JNK-activated Bax lysosomal translocation in neuronal cells.
Toxicology letters
Tianji L,Dingbang H,Xiao C,Xiaojing M,Fei Z,Bin W
Tue Mar 01 00:00:00 EST 2022
Cathepsin L-containing exosomes from α-synuclein-activated microglia induce neurotoxicity through the P2X7 receptor.
NPJ Parkinson's disease
Jiang T,Xu C,Gao S,Zhang J,Zheng J,Wu X,Lu Q,Cao L,Yang D,Xu J,Chen X
Thu Oct 06 00:00:00 EDT 2022
Lysosomal dysfunction is associated with NLRP3 inflammasome activation in chronic unpredictable mild stress-induced depressive mice.
Behavioural brain research
Li MM,Wang X,Chen XD,Yang HL,Xu HS,Zhou P,Gao R,Zhang N,Wang J,Jiang L,Liu N
Fri Aug 26 00:00:00 EDT 2022
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy.
Aging cell
Sun J,Li Y,Yang X,Dong W,Yang J,Hu Q,Zhang C,Fang H,Liu A
Sat Jan 01 00:00:00 EST 2022
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy.
Aging cell
Sun J,Li Y,Yang X,Dong W,Yang J,Hu Q,Zhang C,Fang H,Liu A
Sat Jan 01 00:00:00 EST 2022
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.
Redox biology
Ouyang S,Li H,Lou L,Huang Q,Zhang Z,Mo J,Li M,Lu J,Zhu K,Chu Y,Ding W,Zhu J,Lin Z,Zhong L,Wang J,Yue P,Turkson J,Liu P,Wang Y,Zhang X
Wed Jun 01 00:00:00 EDT 2022
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Fan Y,Lu J,Liu J,Zhang R,Yu Z,Guan S
Mon Nov 01 00:00:00 EDT 2021
Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR-p70S6K pathway.
FEBS open bio
Zuo SQ,Li C,Liu YL,Tan YH,Wan X,Xu T,Li Q,Wang L,Wu YL,Deng FM,Tang B
Fri Oct 01 00:00:00 EDT 2021
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Microorganisms
Yuan L,Chu B,Chen S,Li Y,Liu N,Zhu Y,Zhou D
Tue Nov 16 00:00:00 EST 2021
Curcumin analogue AI-44 alleviates MSU-induced gouty arthritis in mice via inhibiting cathepsin B-mediated NLRP3 inflammasome activation.
International immunopharmacology
Gu Y,Zhu Y,Deng G,Liu S,Sun Y,Lv W
Thu Apr 01 00:00:00 EDT 2021
Curcumin analogue AI-44 alleviates MSU-induced gouty arthritis in mice via inhibiting cathepsin B-mediated NLRP3 inflammasome activation.
International immunopharmacology
Gu Y,Zhu Y,Deng G,Liu S,Sun Y,Lv W
Thu Apr 01 00:00:00 EDT 2021
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Environmental science and pollution research international
Jiang L,Qiu T,Yao X,Chen H,Yao K,Sun X,Yang G,Jiang L,Zhang C,Wang N,Zhang H,Liu X
Wed Dec 01 00:00:00 EST 2021
CTSB Knockdown Inhibits Proliferation and Tumorigenesis in HL-60 Cells.
International journal of medical sciences
Peng S,Yang Q,Li H,Pan Y,Wang J,Hu P,Zhang N
Mon Oct 18 00:00:00 EDT 2021
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Cell death & disease
Hu J,Ding X,Tian S,Chu Y,Liu Z,Li Y,Li X,Wang G,Wang L,Wang Z
Mon Apr 12 00:00:00 EDT 2021
Sodium-Glucose Co-transporter-2 Inhibitor of Dapagliflozin Attenuates Myocardial Ischemia/Reperfusion Injury by Limiting NLRP3 Inflammasome Activation and Modulating Autophagy.
Frontiers in cardiovascular medicine
Yu YW,Que JQ,Liu S,Huang KY,Qian L,Weng YB,Rong FN,Wang L,Zhou YY,Xue YJ,Ji KT
Fri Jan 28 00:00:00 EST 2022
Autophagy Contributes to the Rapamycin-Induced Improvement of Otitis Media.
Frontiers in cellular neuroscience
Xie D,Zhao T,Zhang X,Kui L,Wang Q,Wu Y,Zheng T,Ma P,Zhang Y,Molteni H,Geng R,Yang Y,Li B,Zheng QY
Wed Feb 16 00:00:00 EST 2022
A proteomic approach towards understanding the pathogenesis of Mooren's ulcer.
Experimental eye research
Chi H,Hao W,Qi X,Zhang T,Dong Y,Gao H,Wei C,Shi W
Thu Apr 01 00:00:00 EDT 2021
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Nature
Zhang J,Velmeshev D,Hashimoto K,Huang YH,Hofmann JW,Shi X,Chen J,Leidal AM,Dishart JG,Cahill MK,Kelley KW,Liddelow SA,Seeley WW,Miller BL,Walther TC,Farese RV,Taylor JP,Ullian EM,Huang B,Debnath J,Wittmann T,Kriegstein AR,Huang EJ
Tue Dec 01 00:00:00 EST 2020
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Nature
Zhang J,Velmeshev D,Hashimoto K,Huang YH,Hofmann JW,Shi X,Chen J,Leidal AM,Dishart JG,Cahill MK,Kelley KW,Liddelow SA,Seeley WW,Miller BL,Walther TC,Farese RV,Taylor JP,Ullian EM,Huang B,Debnath J,Wittmann T,Kriegstein AR,Huang EJ
Tue Dec 01 00:00:00 EST 2020
Cilostazol alleviate nicotine induced cardiomyocytes hypertrophy through modulation of autophagy by CTSB/ROS/p38MAPK/JNK feedback loop.
International journal of biological sciences
Wang SY,Ni X,Hu KQ,Meng FL,Li M,Ma XL,Meng TT,Wu HH,Ge D,Zhao J,Li Y,Su GH
Wed Nov 10 00:00:00 EST 2021
Nicotine induces cardiac toxicity through blocking mitophagic clearance in young adult rat.
Life sciences
Jia G,Meng Z,Liu C,Ma X,Gao J,Liu J,Guo R,Yan Z,Christopher T,Lopez B,Liu W,Dai H,Lau WB,Jiao X,Zhao J,Wang ZX,Cao J,Wang Y
Tue Sep 15 00:00:00 EDT 2020
Heat shock factor 4 regulates lysosome activity by modulating the αB-crystallin-ATP6V1A-mTOR complex in ocular lens.
Biochimica et biophysica acta. General subjects
Cui X,Feng R,Wang J,Du C,Pi X,Chen D,Li J,Li H,Zhang J,Zhang J,Mu H,Zhang F,Liu M,Hu Y
Sun Mar 01 00:00:00 EST 2020
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Cell proliferation
Sheng J,Shen L,Sun L,Zhang X,Cui R,Wang L
Wed May 01 00:00:00 EDT 2019
GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus.
Emerging microbes & infections
Chen D,Hou Z,Jiang D,Zheng M,Li G,Zhang Y,Li R,Lin H,Chang J,Zeng H,Guo JT,Zhao X
Wed Jan 15 00:00:00 EST 2020
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
European journal of nutrition
Dong Y,Xu M,Kalueff AV,Song C
Wed Aug 01 00:00:00 EDT 2018
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
European journal of nutrition
Dong Y,Xu M,Kalueff AV,Song C
Wed Aug 01 00:00:00 EDT 2018
Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
Toxicology and applied pharmacology
He R,Shi X,Zhou M,Zhao Y,Pan S,Zhao C,Guo X,Wang M,Li X,Qin R
Mon Oct 01 00:00:00 EDT 2018
Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB.
Toxicology and applied pharmacology
He R,Shi X,Zhou M,Zhao Y,Pan S,Zhao C,Guo X,Wang M,Li X,Qin R
Mon Oct 01 00:00:00 EDT 2018
Promotion of autophagosome-lysosome fusion via salvianolic acid A-mediated SIRT1 up-regulation ameliorates alcoholic liver disease.
RSC advances
Shi X,Sun R,Zhao Y,Fu R,Wang R,Zhao H,Wang Z,Tang F,Zhang N,Tian X,Yao J
Wed May 30 00:00:00 EDT 2018
The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability.
Autophagy
Wang D,Zhang J,Jiang W,Cao Z,Zhao F,Cai T,Aschner M,Luo W
Thu May 04 00:00:00 EDT 2017
The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability.
Autophagy
Wang D,Zhang J,Jiang W,Cao Z,Zhao F,Cai T,Aschner M,Luo W
Thu May 04 00:00:00 EDT 2017
Adipocyte-derived exosomes promote lung cancer metastasis by increasing MMP9 activity via transferring MMP3 to lung cancer cells.
Oncotarget
Wang J,Wu Y,Guo J,Fei X,Yu L,Ma S
Tue Oct 10 00:00:00 EDT 2017
Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux.
Nutrients
Xie X,Yi W,Zhang P,Wu N,Yan Q,Yang H,Tian C,Xiang S,Du M,Getachew Assefa E,Zuo X,Ying C
Sun May 14 00:00:00 EDT 2017
Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux.
Nutrients
Xie X,Yi W,Zhang P,Wu N,Yan Q,Yang H,Tian C,Xiang S,Du M,Getachew Assefa E,Zuo X,Ying C
Sun May 14 00:00:00 EDT 2017
A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells.
Cell death & disease
Fu W,Li X,Lu X,Zhang L,Li R,Zhang N,Liu S,Yang X,Wang Y,Zhao Y,Meng X,Zhu WG
Thu Oct 05 00:00:00 EDT 2017
A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells.
Cell death & disease
Fu W,Li X,Lu X,Zhang L,Li R,Zhang N,Liu S,Yang X,Wang Y,Zhao Y,Meng X,Zhu WG
Thu Oct 05 00:00:00 EDT 2017
NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy.
Cell death & disease
Wang H,Li W,Xu J,Zhang T,Zuo D,Zhou Z,Lin B,Wang G,Wang Z,Sun W,Sun M,Chang S,Cai Z,Hua Y
Thu Sep 14 00:00:00 EDT 2017
NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy.
Cell death & disease
Wang H,Li W,Xu J,Zhang T,Zuo D,Zhou Z,Lin B,Wang G,Wang Z,Sun W,Sun M,Chang S,Cai Z,Hua Y
Thu Sep 14 00:00:00 EDT 2017
Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients.
Oncology letters
Sun T,Jiang D,Zhang L,Su Q,Mao W,Jiang C
Fri Jan 01 00:00:00 EST 2016
Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients.
Oncology letters
Sun T,Jiang D,Zhang L,Su Q,Mao W,Jiang C
Fri Jan 01 00:00:00 EST 2016
Expression of cystatin C and its effect on EC9706 cells in esophageal carcinoma.
International journal of clinical and experimental pathology
Yan Y,Zhou K,Wang L,Zhou Y,Chen X,Fan Q
Wed Oct 05 00:00:00 EDT 2016
Expression of cystatin C and its effect on EC9706 cells in esophageal carcinoma.
International journal of clinical and experimental pathology
Yan Y,Zhou K,Wang L,Zhou Y,Chen X,Fan Q
Wed Oct 05 00:00:00 EDT 2016
Host-derived, pore-forming toxin-like protein and trefoil factor complex protects the host against microbial infection.
Proceedings of the National Academy of Sciences of the United States of America
Xiang Y,Yan C,Guo X,Zhou K,Li S,Gao Q,Wang X,Zhao F,Liu J,Lee WH,Zhang Y
Tue May 06 00:00:00 EDT 2014
Host-derived, pore-forming toxin-like protein and trefoil factor complex protects the host against microbial infection.
Proceedings of the National Academy of Sciences of the United States of America
Xiang Y,Yan C,Guo X,Zhou K,Li S,Gao Q,Wang X,Zhao F,Liu J,Lee WH,Zhang Y
Tue May 06 00:00:00 EDT 2014
