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Product Details
PA5-21535
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 32 and 265 (P25774) of Cathepsin S
Conjugate
Form
Liquid
Concentration
0.67 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11153693
Product Specific Information
Recommended positive controls: HeLa, rat brain.
Predicted reactivity: Dog (89%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein CTSS, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The protein can function as an elastase over a broad pH range in alveolar macrophages.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cathepsin S
Gene Aliases: CTSS
UniProt ID: (Human) P25774, (Rat) Q02765
Entrez Gene ID: (Human) 1520, (Rat) 50654
toll-like receptor signaling pathway
adaptive immune response
proteolysis
immune response
response to acidic pH
protein processing
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
extracellular matrix disassembly
collagen catabolic process
basement membrane disassembly
antigen processing and presentation of peptide antigen
proteolysis involved in cellular protein catabolic process
cellular response to thyroid hormone stimulus
positive regulation of cation channel activity
metanephros development
bone resorption
positive regulation of inflammatory response
regulation of sensory perception of pain
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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