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Invitrogen
Clathrin Heavy Chain Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 5
Clathrin Heavy Chain Antibody (PA5-25804) in IHC (P)
Immunohistochemistry analysis of Clathrin Heavy Chain in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with Clathrin Heavy Chain polyclonal antibody (Product # PA5-25804) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-25804
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 1019-1048 amino acids from the central region of human CLTC
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2543304
Product Specific Information
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
Target Information
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain on chromosome 17; Clathrin heavy chain on chromosome 22; clathrin, heavy chain (Hc); clathrin, heavy chain-like 1; clathrin, heavy polypeptide (Hc); Clathrin, heavy polypeptide D; clathrin, heavy polypeptide-like 1; clathrin, heavy polypeptide-like 2; CLH-17; CLH-22
Gene Aliases: CHC; CHC17; CHC22; CLH-17; CLH17; CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD; Hc; KIAA0034
UniProt ID: (Human) Q00610, (Human) P53675
Entrez Gene ID: (Human) 1213, (Human) 8218
osteoblast differentiation
intracellular protein transport
receptor-mediated endocytosis
mitotic nuclear division
antigen processing and presentation of exogenous peptide antigen via MHC class II
receptor internalization
transferrin transport
retrograde transport, endosome to Golgi
Wnt signaling pathway, planar cell polarity pathway
negative regulation of hyaluronan biosynthetic process
negative regulation of protein localization to plasma membrane
signal transduction
anatomical structure morphogenesis
positive regulation of glucose import
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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