Product References
Nanotubes from bacteriophage tail sheath proteins: internalisation by cancer cells and macrophages.
Nanoscale advances
Gabrielaitis D,Zitkute V,Saveikyte L,Labutyte G,Skapas M,Meskys R,Casaite V,Sasnauskiene A,Neniskyte U
MA1-065 was used in Western Blotting to demonstrate that gp053 nanotubes retained the cargo's enzymatic activity post-assembly and had the capacity to enter cancer cells.
Tue Jul 11 00:00:00 EDT 2023
Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx).
eLife
Damstra HGJ,Mohar B,Eddison M,Akhmanova A,Kapitein LC,Tillberg PW
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunocytochemistry
Fri Feb 18 00:00:00 EST 2022
The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state.
Nature communications
Atwal S,Wongsantichon J,Giengkam S,Saharat K,Pittayasathornthun YJ,Chuenklin S,Wang LC,Chung T,Huh H,Lee SH,Sobota RM,Salje J
MA1-065 was used in Immunocytochemistry-immunoflourescence to show that Ot bacteria that have budded out of host cells are in a distinct developmental stage compared with intracellular bacteria.
Thu Jun 23 00:00:00 EDT 2022
NG2/CSPG4 regulates cartilage degeneration during TMJ osteoarthritis.
Frontiers in dental medicine
Reed DA,Zhao Y,Bagheri Varzaneh M,Shin JS,Rozynek J,Miloro M,Han M
MA1-065 was used in Immunocytochemistry to implicate NG2/CSPG4 in the mechanical homeostasis of temporomandibular joint (TMJ) cartilage and in the progression of degenerative arthropathies including osteoarthritis.
Thu Feb 02 00:00:00 EST 2023
Load adaptation by endocytic actin networks.
Molecular biology of the cell
Kaplan C,Kenny SJ,Chen X,Schöneberg J,Sitarska E,Diz-Muñoz A,Akamatsu M,Xu K,Drubin DG
MA1-065 was used in Immunocytochemistry-immunofluorescence to propose that actin assembly increases in response to increased load to ensure CME robustness over a range of plasma membrane tensions.
Sun May 15 00:00:00 EDT 2022
Vibropolyfection: coupling polymer-mediated gene delivery to mechanical stimulation to enhance transfection of adherent cells.
Journal of nanobiotechnology
Ponti F,Bono N,Russo L,Bigini P,Mantovani D,Candiani G
MA1-065 was used in Immunocytochemistry-immunoflourescence to devise a brand-new gene delivery strategy to boost dramatically the transfection efficiency of two gold standard nucleic acid (NA)/polymer nanoparticles (polyplexes) in vitro.
Sat Aug 06 00:00:00 EDT 2022
The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells.
Nature communications
Prasai B,Haber GJ,Strub MP,Ahn R,Ciemniecki JA,Sochacki KA,Taraska JW
MA1-065 was used in Immunocytochemistry to propose that the circumferential distribution of Rabs and Rab-effectors could aid in the efficient transport, capture, docking, and rapid fusion of calcium-triggered exocytic vesicles in excitable cells.
Fri Jun 25 00:00:00 EDT 2021
Physiological blood-brain transport is impaired with age by a shift in transcytosis.
Nature
Yang AC,Stevens MY,Chen MB,Lee DP,Stähli D,Gate D,Contrepois K,Chen W,Iram T,Zhang L,Vest RT,Chaney A,Lehallier B,Olsson N,du Bois H,Hsieh R,Cropper HC,Berdnik D,Li L,Wang EY,Traber GM,Bertozzi CR,Luo J,Snyder MP,Elias JE,Quake SR,James ML,Wyss-Coray T
MA1-065 was used in Immunocytochemistry-immunoflourescence to reveal the extent of physiological protein transcytosis to the healthy brain, a mechanism of widespread blood-brain barrier dysfunction with age and a strategy for enhanced drug delivery.
Wed Jul 01 00:00:00 EDT 2020
Acute Statin Treatment Improves Antibody Accumulation in EGFR- and PSMA-Expressing Tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research
Pereira PMR,Mandleywala K,Ragupathi A,Lewis JS
MA1-065 was used in Western Blot to determined the potential of lovastatin, simvastatin, and rosuvastatin in preclinically modulating epidermal growth factor receptor (EGFR) and prostate-specific membrane antigen receptor density at the tumor cell surface.
Tue Dec 01 00:00:00 EST 2020
HHV-7 U21 exploits Golgi quality control carriers to reroute class I MHC molecules to lysosomes.
Molecular biology of the cell
Dirck AT,Whyte ML,Hudson AW
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunocytochemistry
Sat Feb 01 00:00:00 EST 2020
HHV-7 U21 exploits Golgi quality control carriers to reroute class I MHC molecules to lysosomes.
Molecular biology of the cell
Dirck AT,Whyte ML,Hudson AW
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunocytochemistry
Sat Feb 01 00:00:00 EST 2020
TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversions.
Molecular biology of the cell
Aki S,Yoshioka K,Takuwa N,Takuwa Y
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunocytochemistry
Sun Mar 01 00:00:00 EST 2020
TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversions.
Molecular biology of the cell
Aki S,Yoshioka K,Takuwa N,Takuwa Y
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunocytochemistry
Sun Mar 01 00:00:00 EST 2020
Structurally distinct endocytic pathways for B cell receptors in B lymphocytes.
Molecular biology of the cell
Roberts AD,Davenport TM,Dickey AM,Ahn R,Sochacki KA,Taraska JW
MA1-065 was used in Immunocytochemistry-immunoflourescence to study the mechanism of antigen-induced BCR clustering and internalisation in the B cell line with use of fluorescence.
Tue Dec 01 00:00:00 EST 2020
Structurally distinct endocytic pathways for B cell receptors in B lymphocytes.
Molecular biology of the cell
Roberts AD,Davenport TM,Dickey AM,Ahn R,Sochacki KA,Taraska JW
MA1-065 was used in Immunocytochemistry-immunoflourescence to study the mechanism of antigen-induced BCR clustering and internalisation in the B cell line with use of fluorescence.
Tue Dec 01 00:00:00 EST 2020
A unique role for clathrin light chain A in cell spreading and migration.
Journal of cell science
Tsygankova OM,Keen JH
MA1-065 was used in Immunocytochemistry-immunoflourescence to comprise the first identification of CLCa-specific functions, with implications for normal and neoplastic integrin-based signaling and cell migration.
Wed May 15 00:00:00 EDT 2019
Characterizing chloride-dependent acidification in brain clathrin-coated vesicles 1.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Weston MR,Mindell JA
MA1-065 was used in Immunoprecipitation to determine the identity and function of this presumed Cl- transporting protein.
Sat Jun 01 00:00:00 EDT 2019
A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits.
Cell
Almeida-Souza L,Frank RAW,García-Nafría J,Colussi A,Gunawardana N,Johnson CM,Yu M,Howard G,Andrews B,Vallis Y,McMahon HT
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunofluorescence
Thu Jul 12 00:00:00 EDT 2018
Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees.
Cell systems
Zlatic SA,Vrailas-Mortimer A,Gokhale A,Carey LJ,Scott E,Burch R,McCall MM,Rudin-Rush S,Davis JB,Hartwig C,Werner E,Li L,Petris M,Faundez V
MA1-065 was used in Western Blotting to obtain mechanistic information by comparing proteomes of cells from individuals with rare disorders with proteomes from their disease-free consanguineous relatives.
Wed Mar 28 00:00:00 EDT 2018
Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry.
PLoS pathogens
Ford C,Nans A,Boucrot E,Hayward RD
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunocytochemistry
Tue May 01 00:00:00 EDT 2018
ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Krey JF,Dumont RA,Wilmarth PA,David LL,Johnson KR,Barr-Gillespie PG
MA1-065 was used in Immunohistochemistry-immunofluorescence to characterise ELMO domain-containing protein 1 control of trafficking.
Wed Jan 24 00:00:00 EST 2018
Mechanisms of integrin αVβ5 clustering in flat clathrin lattices.
Journal of cell science
Zuidema A,Wang W,Kreft M,Te Molder L,Hoekman L,Bleijerveld OB,Nahidiazar L,Janssen H,Sonnenberg A
MA1-065 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot to indicate that clustering of integrin αVβ5 in FCLs is dictated by the β5 subunit cytoplasmic domain, cellular tension and recruitment of specific adaptor proteins to the β5 subunit cytoplasmic domains.
Mon Nov 05 00:00:00 EST 2018
Mechanisms of integrin αVβ5 clustering in flat clathrin lattices.
Journal of cell science
Zuidema A,Wang W,Kreft M,Te Molder L,Hoekman L,Bleijerveld OB,Nahidiazar L,Janssen H,Sonnenberg A
MA1-065 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot to indicate that clustering of integrin αVβ5 in FCLs is dictated by the β5 subunit cytoplasmic domain, cellular tension and recruitment of specific adaptor proteins to the β5 subunit cytoplasmic domains.
Mon Nov 05 00:00:00 EST 2018
Nanoscale manipulation of membrane curvature for probing endocytosis in live cells.
Nature nanotechnology
Zhao W,Hanson L,Lou HY,Akamatsu M,Chowdary PD,Santoro F,Marks JR,Grassart A,Drubin DG,Cui Y,Cui B
MA1-065 was used in Immunocytochemistry to explore how the plasma membrane curvature affects the activities of endocytic proteins.
Tue Aug 01 00:00:00 EDT 2017
An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.
Frontiers in molecular neuroscience
Poulsen ET,Iannuzzi F,Rasmussen HF,Maier TJ,Enghild JJ,Jørgensen AL,Matrone C
MA1065 was used in immunocytochemistry and western blot to study amyloid precursor protein Tyr phosphorylation in mouse model of Alzheimer's disease
Mon Sep 25 00:00:00 EDT 2023
An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.
Frontiers in molecular neuroscience
Poulsen ET,Iannuzzi F,Rasmussen HF,Maier TJ,Enghild JJ,Jørgensen AL,Matrone C
MA1065 was used in immunocytochemistry and western blot to study amyloid precursor protein Tyr phosphorylation in mouse model of Alzheimer's disease
Mon Sep 25 00:00:00 EDT 2023
An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.
Frontiers in molecular neuroscience
Poulsen ET,Iannuzzi F,Rasmussen HF,Maier TJ,Enghild JJ,Jørgensen AL,Matrone C
MA1065 was used in immunocytochemistry and western blot to study amyloid precursor protein Tyr phosphorylation in mouse model of Alzheimer's disease
Mon Sep 25 00:00:00 EDT 2023
Influenza virus genome reaches the plasma membrane via a modified endoplasmic reticulum and Rab11-dependent vesicles.
Nature communications
de Castro Martin IF,Fournier G,Sachse M,Pizarro-Cerda J,Risco C,Naffakh N
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Western Blot
Thu Nov 09 00:00:00 EST 2017
Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness.
The Journal of biological chemistry
Bugge M,Bergstrom B,Eide OK,Solli H,Kjønstad IF,Stenvik J,Espevik T,Nilsen NJ
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Western Blot
Fri Sep 15 00:00:00 EDT 2017
Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors.
Nature communications
Leyton-Puig D,Isogai T,Argenzio E,van den Broek B,Klarenbeek J,Janssen H,Jalink K,Innocenti M
MA1-065 was used in Immunocytochemistry-immunoflourescence to show that clathrin plaques contain the machinery for clathrin-mediated endocytosis and cell adhesion, and associate with both clathrin-coated pits and filamentous actin.
Thu Jul 13 00:00:00 EDT 2017
Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.
Nature structural & molecular biology
Wollscheid HP,Biancospino M,He F,Magistrati E,Molteni E,Lupia M,Soffientini P,Rottner K,Cavallaro U,Pozzoli U,Mapelli M,Walters KJ,Polo S
MA1-065 was used in immunocytochemistry to elucidate the function of the alpha2-linker of myosin VI
Fri Apr 01 00:00:00 EDT 2016
Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.
Nature structural & molecular biology
Wollscheid HP,Biancospino M,He F,Magistrati E,Molteni E,Lupia M,Soffientini P,Rottner K,Cavallaro U,Pozzoli U,Mapelli M,Walters KJ,Polo S
MA1-065 was used in immunocytochemistry to elucidate the function of the alpha2-linker of myosin VI
Fri Apr 01 00:00:00 EDT 2016
Axial superresolution via multiangle TIRF microscopy with sequential imaging and photobleaching.
Proceedings of the National Academy of Sciences of the United States of America
Fu Y,Winter PW,Rojas R,Wang V,McAuliffe M,Patterson GH
MA1-065 was used in immunocytochemistry to utilize multiangle TIRF microscopy with sequential imaging and photobleaching for axial superresolution
Tue Apr 19 00:00:00 EDT 2016
Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis.
EMBO reports
Wang C,Wang Y,Hu M,Chai Z,Wu Q,Huang R,Han W,Zhang CX,Zhou Z
MA1-065 was used in immunocytochemistry to characterize inhibition of clathrin-mediated and bulk endocytosis by synaptotagmin-11
Fri Jan 01 00:00:00 EST 2016
High affinity receptor labeling based on basic leucine zipper domain peptides conjugated with pH-sensitive fluorescent dye: Visualization of AMPA-type glutamate receptor endocytosis in living neurons.
Neuropharmacology
Hayashi A,Asanuma D,Kamiya M,Urano Y,Okabe S
MA1-065 was used in immunocytochemistry to establish a method for receptor labeling using a basic leucine zipper domain peptide and its specific binding cassette
Fri Jan 01 00:00:00 EST 2016
madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy.
Molecular biology of the cell
Yi J,Manna A,Barr VA,Hong J,Neuman KC,Samelson LE
MA1065 was used in immunocytochemistry to develop a new multiplex dSTORM imaging strategy to localize epitopes on activated T-cells
Mon Nov 07 00:00:00 EST 2016
Caveolin- and clathrin-independent entry of BKPyV into primary human proximal tubule epithelial cells.
Virology
Zhao L,Marciano AT,Rivet CR,Imperiale MJ
MA1-065 was used in western blot to study the clathrin- and caveolin- independent entry of BKPgammaV into primary human proximal tubule epithelial cells
Sun May 01 00:00:00 EDT 2016
Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells.
PloS one
Chiang CF,Flint M,Lin JS,Spiropoulou CF
MA1065 was used in western blot to elucidate the role of endocytic pathways in Andes virus infection
Tue Jun 13 00:00:00 EDT 2017
Endophilin marks and controls a clathrin-independent endocytic pathway.
Nature
Boucrot E,Ferreira AP,Almeida-Souza L,Debard S,Vallis Y,Howard G,Bertot L,Sauvonnet N,McMahon HT
MA1-065 was used in immunocytochemistry and western blot to identify and characterize a new endocytic route that is called fast endophilin-mediated endocytosis.
Thu Jan 22 00:00:00 EST 2015
Endophilin marks and controls a clathrin-independent endocytic pathway.
Nature
Boucrot E,Ferreira AP,Almeida-Souza L,Debard S,Vallis Y,Howard G,Bertot L,Sauvonnet N,McMahon HT
MA1-065 was used in immunocytochemistry and western blot to identify and characterize a new endocytic route that is called fast endophilin-mediated endocytosis.
Thu Jan 22 00:00:00 EST 2015
Endophilin marks and controls a clathrin-independent endocytic pathway.
Nature
Boucrot E,Ferreira AP,Almeida-Souza L,Debard S,Vallis Y,Howard G,Bertot L,Sauvonnet N,McMahon HT
MA1-065 was used in immunocytochemistry and western blot to identify and characterize a new endocytic route that is called fast endophilin-mediated endocytosis.
Thu Jan 22 00:00:00 EST 2015
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Nature neuroscience
Zhao Z,Sagare AP,Ma Q,Halliday MR,Kong P,Kisler K,Winkler EA,Ramanathan A,Kanekiyo T,Bu G,Owens NC,Rege SV,Si G,Ahuja A,Zhu D,Miller CA,Schneider JA,Maeda M,Maeda T,Sugawara T,Ichida JK,Zlokovic BV
MA1-065 was used in immunocytochemistry and western blot to determine the role of PICALM in Abeta transcytosis across the blood brain barrier.
Wed Jul 01 00:00:00 EDT 2015
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Nature neuroscience
Zhao Z,Sagare AP,Ma Q,Halliday MR,Kong P,Kisler K,Winkler EA,Ramanathan A,Kanekiyo T,Bu G,Owens NC,Rege SV,Si G,Ahuja A,Zhu D,Miller CA,Schneider JA,Maeda M,Maeda T,Sugawara T,Ichida JK,Zlokovic BV
MA1-065 was used in immunocytochemistry and western blot to determine the role of PICALM in Abeta transcytosis across the blood brain barrier.
Wed Jul 01 00:00:00 EDT 2015
Lack of CD2AP disrupts Glut4 trafficking and attenuates glucose uptake in podocytes.
Journal of cell science
Tolvanen TA,Dash SN,Polianskyte-Prause Z,Dumont V,Lehtonen S
MA1-065 was used in Immunoprecipitation to investigate the role of CD2-associated protein in insulin-dependent glucose transporter 4 trafficking and glucose uptake.
Tue Dec 15 00:00:00 EST 2015
The X-linked mental retardation protein OPHN1 interacts with Homer1b/c to control spine endocytic zone positioning and expression of synaptic potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nakano-Kobayashi A,Tai Y,Nadif Kasri N,Van Aelst L
MA1-065 was used in immunohistochemistry to study the interaction between the X-linked mental retardation protein OPHN1 and Homer1b/c and its roel in local endocytic recycling of AMPA receptors
Wed Jun 25 00:00:00 EDT 2014
The X-linked mental retardation protein OPHN1 interacts with Homer1b/c to control spine endocytic zone positioning and expression of synaptic potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nakano-Kobayashi A,Tai Y,Nadif Kasri N,Van Aelst L
MA1-065 was used in immunohistochemistry to study the interaction between the X-linked mental retardation protein OPHN1 and Homer1b/c and its roel in local endocytic recycling of AMPA receptors
Wed Jun 25 00:00:00 EDT 2014
Characterization of human astrovirus cell entry.
Journal of virology
Méndez E,Muñoz-Yañez C,Sánchez-San Martín C,Aguirre-Crespo G,Baños-Lara Mdel R,Gutierrez M,Espinosa R,Acevedo Y,Arias CF,López S
MA1-065 was used in immunocytochemistry and western blot to study the cell entry mechanism of human astrovirus
Sat Mar 01 00:00:00 EST 2014
Alternative endocytosis pathway for productive entry of hepatitis C virus.
The Journal of general virology
Matsuda M,Suzuki R,Kataoka C,Watashi K,Aizaki H,Kato N,Matsuura Y,Suzuki T,Wakita T
MA1-065 was used in immunocytochemistry to investigate the mechanisms of hepatitis C virus entry into multiple permissive human hepatocyte-derived cells
Mon Dec 01 00:00:00 EST 2014
Functional coupling of chloride-proton exchanger ClC-5 to gastric H+,K+-ATPase.
Biology open
Takahashi Y,Fujii T,Fujita K,Shimizu T,Higuchi T,Tabuchi Y,Sakamoto H,Naito I,Manabe K,Uchida S,Sasaki S,Ikari A,Tsukada K,Sakai H
MA1-065 was used in western blot to study CIC-5-to-gastric H(+)/K(+)-ATPase functional coupling
Wed Jan 15 00:00:00 EST 2014
Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways.
mBio
Olofsson A,Nygård Skalman L,Obi I,Lundmark R,Arnqvist A
MA1-065 was used in immunocytochemistry to study the role of clathrin-dependent and clathrin-independent routes in the uptake of Helicobacter pylori vesicles by gastric epithelial cells
Tue May 20 00:00:00 EDT 2014
Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yamada H,Abe T,Satoh A,Okazaki N,Tago S,Kobayashi K,Yoshida Y,Oda Y,Watanabe M,Tomizawa K,Matsui H,Takei K
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunohistochemistry
Wed Mar 06 00:00:00 EST 2013
Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yamada H,Abe T,Satoh A,Okazaki N,Tago S,Kobayashi K,Yoshida Y,Oda Y,Watanabe M,Tomizawa K,Matsui H,Takei K
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunohistochemistry
Wed Mar 06 00:00:00 EST 2013
The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.
Journal of lipid research
Sorrentino V,Nelson JK,Maspero E,Marques ARA,Scheer L,Polo S,Zelcer N
MA1-065 was used in immunocytochemistry to study the mechanism underlying the LXR-IDOL-mediated pathway of LDLR internalization and degradation
Thu Aug 01 00:00:00 EDT 2013
Netrin-1-induced activation of Notch signaling mediates glioblastoma cell invasion.
Journal of cell science
Ylivinkka I,Hu Y,Chen P,Rantanen V,Hautaniemi S,Nyman TA,Keski-Oja J,Hyytiäinen M
MA1-065 was used in immunocytochemistry to study the role of Notch signaling in the mechanism by which netrin-1 promotes glioblastoma cell invasiveness
Sat Jun 01 00:00:00 EDT 2013
Synaptotagmin 1 is necessary for the Ca2+ dependence of clathrin-mediated endocytosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yao LH,Rao Y,Varga K,Wang CY,Xiao P,Lindau M,Gong LW
MA1-065 was used in blocking or activating experiment to investigate the importance of calcium ion in clathrin-mediated endocytosis
Wed Mar 14 00:00:00 EDT 2012
Rift Valley fever virus strain MP-12 enters mammalian host cells via caveola-mediated endocytosis.
Journal of virology
Harmon B,Schudel BR,Maar D,Kozina C,Ikegami T,Tseng CT,Negrete OA
MA1-065 was used in western blot to study the role of caveolin-1-mediated endocytosis in the entry of the zoonotic Rift Valley virus into mammalian cells
Sat Dec 01 00:00:00 EST 2012
Cell surface ceramide controls translocation of transferrin receptor to clathrin-coated pits.
Cellular signalling
Abdel Shakor AB,Atia MM,Kwiatkowska K,Sobota A
MA1-065 was used in western blot to investigate the role of cell surface ceramide in transferrin receptor translocation and internalization
Thu Mar 01 00:00:00 EST 2012
Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.
Molecular biology of the cell
Prabhu Y,Burgos PV,Schindler C,Farías GG,Magadán JG,Bonifacino JS
MA1-065 was used in western blot to study the maintenance of BACE1 proteolysis of APP in the absence of AP-2-mediated BACE1 endocytosis
Fri Jun 01 00:00:00 EDT 2012
Multi-colour direct STORM with red emitting carbocyanines.
Biology of the cell
Lampe A,Haucke V,Sigrist SJ,Heilemann M,Schmoranzer J
MA1-065 was used in immunocytochemistry to develop Direct stochastic optical reconstruction microscopy for biological application
Sun Apr 01 00:00:00 EDT 2012
The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA.
PloS one
Varsano T,Taupin V,Guo L,Baterina OY,Farquhar MG
MA1-065 was used in immunocytochemistry to study the role of GIPC in modulating LPA1 receptor trafficking and the cellular response to lysophosphatidic acid
Tue Jun 25 00:00:00 EDT 2013
Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition.
Cell
von Kleist L,Stahlschmidt W,Bulut H,Gromova K,Puchkov D,Robertson MJ,MacGregor KA,Tomilin N,Pechstein A,Chau N,Chircop M,Sakoff J,von Kries JP,Saenger W,Kräusslich HG,Shupliakov O,Robinson PJ,McCluskey A,Haucke V
MA1-065 was used in immunocytochemistry to investigate the coated pit dynamics and the role of the clathrin terminal domain in its regulation
Fri Aug 05 00:00:00 EDT 2011
Fast, three-dimensional super-resolution imaging of live cells.
Nature methods
Jones SA,Shim SH,He J,Zhuang X
MA1-065 was used in immunocytochemistry to develop a system for rapid, high resolution live cell imaging in 3-dimensions
Wed Jun 01 00:00:00 EDT 2011
Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.
Nature cell biology
Doyon JB,Zeitler B,Cheng J,Cheng AT,Cherone JM,Santiago Y,Lee AH,Vo TD,Doyon Y,Miller JC,Paschon DE,Zhang L,Rebar EJ,Gregory PD,Urnov FD,Drubin DG
Published figure using Clathrin Heavy Chain monoclonal antibody (Product # MA1-065) in Immunofluorescence
Tue Mar 01 00:00:00 EST 2011
Sphingomyelin synthase 1-generated sphingomyelin plays an important role in transferrin trafficking and cell proliferation.
The Journal of biological chemistry
Shakor ABA,Taniguchi M,Kitatani K,Hashimoto M,Asano S,Hayashi A,Nomura K,Bielawski J,Bielawska A,Watanabe K,Kobayashi T,Igarashi Y,Umehara H,Takeya H,Okazaki T
MA1-065 was used in immunocytochemistry to investigate the role of sphingomyelin in transferrin trafficking and cell proliferation
Fri Oct 14 00:00:00 EDT 2011
Intracellular trafficking of hyaluronic acid-chitosan oligomer-based nanoparticles in cultured human ocular surface cells.
Molecular vision
Contreras-Ruiz L,de la Fuente M,Párraga JE,López-García A,Fernández I,Seijo B,Sánchez A,Calonge M,Diebold Y
MA1-065 was used in immunohistochemistry to investigate the internalization of hyaluronic acid-chitosan oligomer-based nanoparticles in cultured ocular surface cells
Thu Jan 27 00:00:00 EST 2011
Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system.
Nature cell biology
Wu M,Huang B,Graham M,Raimondi A,Heuser JE,Zhuang X,De Camilli P
MA1-065 was used in immunohistochemistry to develop a cell-free system to study the molecular mechanisms involved in membrane transport
Wed Sep 01 00:00:00 EDT 2010
EphA8-ephrinA5 signaling and clathrin-mediated endocytosis is regulated by Tiam-1, a Rac-specific guanine nucleotide exchange factor.
Molecules and cells
Yoo S,Shin J,Park S
MA1-065 was used in immunocytochemistry to investigate the role of Rac-specific guanine nucleotide exchange factor Tiam-1 in EphA8-ephrinA5 signaling and endocytosis
Tue Jun 01 00:00:00 EDT 2010
Ornithine decarboxylase antizyme inhibitor 2 regulates intracellular vesicle trafficking.
Experimental cell research
Kanerva K,Mäkitie LT,Bäck N,Andersson LC
MA1-065 was used in immunocytochemistry to investigate the role of ornithine decarboxylase antizyme inhibitor 2 AZIN2 in the transport of intracellular vesicles
Thu Jul 01 00:00:00 EDT 2010
Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N-cadherin in rat liver epithelial cells.
Molecular biology of the cell
Govindarajan R,Chakraborty S,Johnson KE,Falk MM,Wheelock MJ,Johnson KR,Mehta PP
MA1-065 was used in immunocytochemistry to investigate the regulation of the Cx43 assembly by E-cadherin and N-cadherin
Wed Dec 01 00:00:00 EST 2010
Ebola virus uses clathrin-mediated endocytosis as an entry pathway.
Virology
Bhattacharyya S,Warfield KL,Ruthel G,Bavari S,Aman MJ,Hope TJ
MA1-065 was used in immunocytochemistry to characterize the entry of Ebola virus into human cells
Tue May 25 00:00:00 EDT 2010
Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development.
BMC developmental biology
Bai T,Seebald JL,Kim KE,Ding HM,Szeto DP,Chang HC
MA1-065 was used in immunocytochemistry to investigate the role of cyclin G-associated kinase during neuronal development and neurogenesis in zebrafish
Mon Jan 18 00:00:00 EST 2010
Rapid turnover of spinules at synaptic terminals.
Neuroscience
Tao-Cheng JH,Dosemeci A,Gallant PE,Miller S,Galbraith JA,Winters CA,Azzam R,Reese TS
MA1-065 was used in immunohistochemistry to study the turnover of spinules at synaptic terminals
Tue Apr 21 00:00:00 EDT 2009
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies.
PLoS biology
Pons V,Luyet PP,Morel E,Abrami L,van der Goot FG,Parton RG,Gruenberg J
MA1-065 was used in immunocytochemistry to study the role of Hrs and SNX3 in sorting and membrane invagination within multivesicular bodies
Tue Sep 02 00:00:00 EDT 2008
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.
Science signaling
Ciraolo E,Iezzi M,Marone R,Marengo S,Curcio C,Costa C,Azzolino O,Gonella C,Rubinetto C,Wu H,Dastrù W,Martin EL,Silengo L,Altruda F,Turco E,Lanzetti L,Musiani P,Rückle T,Rommel C,Backer JM,Forni G,Wymann MP,Hirsch E
MA1-065 was used in immunocytochemistry to investigate the role of the p110beta catalytic activity in diabetes and cancer.
Tue Sep 09 00:00:00 EDT 2008
Role of internalization of M2 muscarinic receptor via clathrin-coated vesicles in desensitization of the muscarinic K+ current in heart.
American journal of physiology. Heart and circulatory physiology
Yamanushi TT,Shui Z,Leach RN,Dobrzynski H,Claydon TW,Boyett MR
MA1-065 was used in immunocytochemistry to study the relationship between M2 muscarinic receptor internalization and the muscarinic potassium current in heart
Sun Apr 01 00:00:00 EDT 2007
A role for clathrin in reassembly of the Golgi apparatus.
Molecular biology of the cell
Radulescu AE,Siddhanta A,Shields D
MA1-065 was used in western blot to investigate the role of clathrin during Golgi Apparatus reassembly.
Mon Jan 01 00:00:00 EST 2007
Mass spectrometry analysis of the native protein complex containing actinin-4 in prostate cancer cells.
Molecular & cellular proteomics : MCP
Hara T,Honda K,Shitashige M,Ono M,Matsuyama H,Naito K,Hirohashi S,Yamada T
MA1-065 was used in immunocytochemistry to show that actinin-4 is co-localized with clathrin in prostate cancer cells
Thu Mar 01 00:00:00 EST 2007
Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments.
The Journal of cell biology
Lampugnani MG,Orsenigo F,Gagliani MC,Tacchetti C,Dejana E
MA1-065 was used in immunohistochemistry investigate the roles of the vascular endothelial cadherin during the VEGFR-2 internalization.
Mon Aug 14 00:00:00 EDT 2006
GBF1, a cis-Golgi and VTCs-localized ARF-GEF, is implicated in ER-to-Golgi protein traffic.
Journal of cell science
Zhao X,Claude A,Chun J,Shields DJ,Presley JF,Melançon P
MA1-065 was used in immunocytochemistry to demonstrate the role of GBF1 in COPI membrane recruitment in the early secretory pathway.
Fri Sep 15 00:00:00 EDT 2006
Trimerisation is important for the function of clathrin at the mitotic spindle.
Journal of cell science
Royle SJ,Lagnado L
MA1-065 was used in immunocytochemistry to investigate the importance of trimerization in clathrin's structure for its normal functions
Sun Oct 01 00:00:00 EDT 2006
SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development.
Human molecular genetics
Zhu PP,Soderblom C,Tao-Cheng JH,Stadler J,Blackstone C
MA1-065 was used in immunocytochemistry to study the role of the SPG3A protein atlastin-1 in neural growth cones and axon elongation
Sat Apr 15 00:00:00 EDT 2006
ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.
Molecular and cellular biology
Grewal PK,Boton M,Ramirez K,Collins BE,Saito A,Green RS,Ohtsubo K,Chui D,Marth JD
MA1-065 was used in immunohistochemistry to investigate the roles of the ST6Gal-I during the normal and pathogenic immune signaling.
Sat Jul 01 00:00:00 EDT 2006
Interaction of SPIN90 with syndapin is implicated in clathrin-mediated endocytic pathway in fibroblasts.
Genes to cells : devoted to molecular & cellular mechanisms
Kim SH,Choi HJ,Lee KW,Hong NH,Sung BH,Choi KY,Kim SM,Chang S,Eom SH,Song WK
MA1-065 was used in immunohistochemistry to study the function of SPIN90 in the receptor-mediated endocytic pathway
Sun Oct 01 00:00:00 EDT 2006
Epidermal growth factor receptor exposed to oxidative stress undergoes Src- and caveolin-1-dependent perinuclear trafficking.
The Journal of biological chemistry
Khan EM,Heidinger JM,Levy M,Lisanti MP,Ravid T,Goldkorn T
MA1-065 was used in western blot to investigate the role of oxidative stress during tumorigenesis.
Fri May 19 00:00:00 EDT 2006
TTP specifically regulates the internalization of the transferrin receptor.
Cell
Tosoni D,Puri C,Confalonieri S,Salcini AE,De Camilli P,Tacchetti C,Di Fiore PP
MA1-065 was used in immunohistochemistry to study the regulation of transferrin receptor internalization by the SH3-containing protein TTP
Fri Dec 02 00:00:00 EST 2005
Clathrin-independent endocytosis of ubiquitinated cargos.
Proceedings of the National Academy of Sciences of the United States of America
Sigismund S,Woelk T,Puri C,Maspero E,Tacchetti C,Transidico P,Di Fiore PP,Polo S
MA1-065 was used in immunocytochemistry to investigate the internalization of EGFR mediated by ubiquitination
Tue Feb 22 00:00:00 EST 2005
Analysis of foot-and-mouth disease virus internalization events in cultured cells.
Journal of virology
O'Donnell V,LaRocco M,Duque H,Baxt B
MA1-065 was used in immunocytochemistry to study the internalization of foot-and-mouth disease virus in cultured human cells
Fri Jul 01 00:00:00 EDT 2005
Increased expression of protein C-mannosylation in the aortic vessels of diabetic Zucker rats.
Glycobiology
Ihara Y,Manabe S,Kanda M,Kawano H,Nakayama T,Sekine I,Kondo T,Ito Y
MA1-065 was used in immunocytochemistry to study the increased levels of C-mannosylation of proteins in the aortic vessels of diabetic Zucker rats
Fri Apr 01 00:00:00 EST 2005
Exchange of clathrin, AP2 and epsin on clathrin-coated pits in permeabilized tissue culture cells.
Journal of cell science
Yim YI,Scarselletta S,Zang F,Wu X,Lee DW,Kang YS,Eisenberg E,Greene LE
MA1-065 was used in immunocytochemistry to investigate the mechanism of exchange of clathrin, AP2 and epsin on clathrin-coated pits in permeabilized tissue culture cells
Wed Jun 01 00:00:00 EDT 2005
A novel GTPase-activating protein for ARF6 directly interacts with clathrin and regulates clathrin-dependent endocytosis.
Molecular biology of the cell
Tanabe K,Torii T,Natsume W,Braesch-Andersen S,Watanabe T,Satake M
MA1-065 was used in immunocytochemistry to study SMAP1, a novel GTPase-activating protein for Arf6 that directly binds clathrin and modulates clathrin-mediated endocytosis
Fri Apr 01 00:00:00 EST 2005
Actin dynamics coupled to clathrin-coated vesicle formation at the trans-Golgi network.
The Journal of cell biology
Carreno S,Engqvist-Goldstein AE,Zhang CX,McDonald KL,Drubin DG
MA1-065 was used in immunocytochemistry to investigate the roles of actin and Hip1R during the lysosome biogenesis.
Mon Jun 21 00:00:00 EDT 2004
Differences in endosomal targeting of human (beta)1- and (beta)2-adrenergic receptors following clathrin-mediated endocytosis.
Journal of cell science
Liang W,Curran PK,Hoang Q,Moreland RT,Fishman PH
MA1-065 was used in immunocytochemistry to study the internalization of adrenergic receptors.
Sun Feb 15 00:00:00 EST 2004
RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery.
Molecular biology of the cell
Engqvist-Goldstein AE,Zhang CX,Carreno S,Barroso C,Heuser JE,Drubin DG
MA1-065 was used in immunocytochemistry to investigate the role of Huntingtin interacting protein 1R at the interface between the actin cytoskeleton and the endocytic machinery
Thu Apr 01 00:00:00 EST 2004
Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment.
Molecular biology of the cell
Ivanov AI,Nusrat A,Parkos CA
MA1-065 was used in immunocytochemistry to investigate the mechanism of endocytosis of adherens junction proteins and tight junction proteins in T84 epithelial cells
Thu Jan 01 00:00:00 EST 2004
Detergent-resistant membrane microdomains facilitate Ib oligomer formation and biological activity of Clostridium perfringens iota-toxin.
Infection and immunity
Hale ML,Marvaud JC,Popoff MR,Stiles BG
MA1-065 was used in western blot to locate iota b (Ib) oligomers in detergent-resistant membrane microdomains (DRMs) extracted from Vero cells
Thu Apr 01 00:00:00 EST 2004
PP1 inhibitor induces degradation of RETMEN2A and RETMEN2B oncoproteins through proteosomal targeting.
Cancer research
Carniti C,Perego C,Mondellini P,Pierotti MA,Bongarzone I
MA1-065 was used in immunocytochemistry to investigate the effect of PP1 inhibitor on RETMEN2A and RETMEN2B oncoproteins
Thu May 01 00:00:00 EDT 2003
Spatial regulation of Galphai protein signaling in clathrin-coated membrane microdomains containing GAIP.
Molecular pharmacology
Elenko E,Fischer T,Niesman I,Harding T,McQuistan T,Von Zastrow M,Farquhar MG
MA1-065 was used in immunocytochemistry to study the regulatory mechanisms of Galphai protein signaling in clathrin-coated pits
Tue Jul 01 00:00:00 EDT 2003
Targeted chemical disruption of clathrin function in living cells.
Molecular biology of the cell
Moskowitz HS,Heuser J,McGraw TE,Ryan TA
MA1-065 was used in immunocytochemistry to engineer a novel chemical tool to disrupt clathrin function in living cells.
Sat Nov 01 00:00:00 EST 2003
Sustained stimulation shifts the mechanism of endocytosis from dynamin-1-dependent rapid endocytosis to clathrin- and dynamin-2-mediated slow endocytosis in chromaffin cells.
Proceedings of the National Academy of Sciences of the United States of America
Artalejo CR,Elhamdani A,Palfrey HC
MA1-065 was used in blocking/activating experiments to study the effect of sustained stimulation on endocytosis in chromaffin cells.
Tue Apr 30 00:00:00 EDT 2002
Dynamin is involved in human epithelial cell vacuolation caused by the Helicobacter pylori-produced cytotoxin VacA.
The Journal of clinical investigation
Suzuki J,Ohnsihi H,Shibata H,Wada A,Hirayama T,Iiri T,Ueda N,Kanamaru C,Tsuchida T,Mashima H,Yasuda H,Fujita T
MA1-065 was used in immunocytochemistry to investigate the effect of VacA intoxication on the intracellular localization of clathrin
Thu Feb 01 00:00:00 EST 2001
HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.
The Journal of biological chemistry
Metzler M,Legendre-Guillemin V,Gan L,Chopra V,Kwok A,McPherson PS,Hayden MR
MA1-065 was used in western blot to study the role of HIP1 in clathrin-mediated endocytosis.
Fri Oct 19 00:00:00 EDT 2001
Role of cyclin G-associated kinase in uncoating clathrin-coated vesicles from non-neuronal cells.
The Journal of biological chemistry
Greener T,Zhao X,Nojima H,Eisenberg E,Greene LE
MA1-065 was used in immunocytochemistry to demonstrate the role of cyclin G-associated kinase in endocytic process .
Fri Jan 14 00:00:00 EST 2000
Hsc70 chaperones clathrin and primes it to interact with vesicle membranes.
The Journal of biological chemistry
Jiang R,Gao B,Prasad K,Greene LE,Eisenberg E
MA1-065 was used in immunoprecipitation to investigate the role for Hsc70 in regulating clathrin-coated vesicles uncoating.
Fri Mar 24 00:00:00 EST 2000
Clathrin-coated vesicles bearing GAIP possess GTPase-activating protein activity in vitro.
Proceedings of the National Academy of Sciences of the United States of America
Fischer T,Elenko E,McCaffery JM,DeVries L,Farquhar MG
MA1-065 was used in western blot to study the GTPase-activating protein activity in clathrin-coated vesicles.
Tue Jun 08 00:00:00 EDT 1999
An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles.
The Journal of cell biology
Engqvist-Goldstein AE,Kessels MM,Chopra VS,Hayden MR,Drubin DG
MA1-065 was used in immunocytochemistry to investigate the role of clathrin during endocytosis.
Mon Dec 27 00:00:00 EST 1999
Overexpression of proteins containing tyrosine- or leucine-based sorting signals affects transferrin receptor trafficking.
The Journal of biological chemistry
Nordeng TW,Bakke O
MA1-065 was used in immunocytochemistry to study the effect of the overexpression of proteins containing tyrosine- or leucine-based sorting signals
Fri Jul 23 00:00:00 EDT 1999
Characterization of the adaptor-related protein complex, AP-3.
The Journal of cell biology
Simpson F,Peden AA,Christopoulou L,Robinson MS
MA1-065 was used in immunocytochemistry to investigate the subunits of the adaptor-like complex and their corresponding functional properties
Mon May 19 00:00:00 EDT 1997
Targeting and mistargeting of plasma membrane adaptors in vitro.
The Journal of cell biology
Seaman MN,Ball CL,Robinson MS
MA1-065 was used in immunocytochemistry to investigate the intracellular transport and sequestration of plasma membrane adaptors
Wed Dec 01 00:00:00 EST 1993
100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties.
The Journal of cell biology
Wong DH,Brodsky FM
MA1-065 was used in immunocytochemistry to study coat protein membrane binding properties in the Golgi region
Mon Jun 01 00:00:00 EDT 1992
