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Invitrogen
Claudin 1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 7
Claudin 1 Antibody (PA5-20754) in ICC/IF
Immunofluorescent analysis of 4% paraformaldehyde-fixed HepG2 cells labeling CLDN1 with Claudin 1 Polyclonal Antibody (Product # PA5-20754) at 20 µg/mL, followed by goat anti-rabbit IgG secondary antibody at 1:500 dilution (green) and DAPI staining (blue).
Product Details
PA5-20754
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 20 amino acid peptide near the carboxy terminus of human CLDN1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152708
Product Specific Information
A suggested positive control is HepG2 cell lysate.
PA5-20754 can be used with blocking peptide PEP-0868.
Target Information
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Claudin-1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1
Gene Aliases: AI596271; CLD1; CLDN1; ILVASC; SEMP1; UNQ481/PRO944
UniProt ID: (Human) O95832, (Rat) P56745, (Mouse) O88551
Entrez Gene ID: (Dog) 608207, (Human) 9076, (Rat) 65129, (Mouse) 12737
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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