Product References
Functional Analysis of Gastric Tight Junction Proteins in Xenopus laevis Oocytes.
Membranes
Stein L,Brunner N,Amasheh S
700178 was used in Western Blot, Immunohistochemistry to establish oocytes as an expression and two-cell screening model for tight junction integrity analysis of organ- and tissue-specific claudins by the characterization of homo- and heterophilic trans-interaction dependent on barrier effectors.
Sat Jul 23 00:00:00 EDT 2022
Functional Analysis of Gastric Tight Junction Proteins in Xenopus laevis Oocytes.
Membranes
Stein L,Brunner N,Amasheh S
700178 was used in Western Blot, Immunohistochemistry to establish oocytes as an expression and two-cell screening model for tight junction integrity analysis of organ- and tissue-specific claudins by the characterization of homo- and heterophilic trans-interaction dependent on barrier effectors.
Sat Jul 23 00:00:00 EDT 2022
Functional Analysis of Gastric Tight Junction Proteins in Xenopus laevis Oocytes.
Membranes
Stein L,Brunner N,Amasheh S
700178 was used in Western Blot, Immunohistochemistry to establish oocytes as an expression and two-cell screening model for tight junction integrity analysis of organ- and tissue-specific claudins by the characterization of homo- and heterophilic trans-interaction dependent on barrier effectors.
Sat Jul 23 00:00:00 EDT 2022
Transcriptomic Analysis of Testicular Gene Expression in a Dog Model of Experimentally Induced Cryptorchidism.
Cells
Jhun H,Lee WY,Park JK,Hwang SG,Park HJ
700178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that testicular hyperthermia caused by cryptorchidism affects claudin expression, regulated germ cell death, and the proliferation of Sertoli cells.
Wed Aug 10 00:00:00 EDT 2022
Transcriptomic Analysis of Testicular Gene Expression in a Dog Model of Experimentally Induced Cryptorchidism.
Cells
Jhun H,Lee WY,Park JK,Hwang SG,Park HJ
700178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that testicular hyperthermia caused by cryptorchidism affects claudin expression, regulated germ cell death, and the proliferation of Sertoli cells.
Wed Aug 10 00:00:00 EDT 2022
Asymmetric distribution of dynamin-2 and β-catenin relative to tight junction spikes in alveolar epithelial cells.
Tissue barriers
Lynn KS,Easley KF,Martinez FJ,Reed RC,Schlingmann B,Koval M
700178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest a novel role for dynamin-2 in tight junction spike formation by reorienting junction-associated actin.
Sat Jul 03 00:00:00 EDT 2021
Clinical Significance of CLDN18.2 Expression in Metastatic Diffuse-Type Gastric Cancer.
Journal of gastric cancer
Kim SR,Shin K,Park JM,Lee HH,Song KY,Lee SH,Kim B,Kim SY,Seo J,Kim JO,Roh SY,Kim IH
700178 was used in Immunohistochemistry-immunofluorescence to investigate the clinical significance of CLDN18.2 and other cell-adherens junction molecules (Rho GTPase-activating protein [RhoGAP] and E-cadherin) in metastatic diffuse-type gastric cancer (mDGC).
Tue Dec 01 00:00:00 EST 2020
Clinical Significance of CLDN18.2 Expression in Metastatic Diffuse-Type Gastric Cancer.
Journal of gastric cancer
Kim SR,Shin K,Park JM,Lee HH,Song KY,Lee SH,Kim B,Kim SY,Seo J,Kim JO,Roh SY,Kim IH
700178 was used in Immunohistochemistry-immunofluorescence to investigate the clinical significance of CLDN18.2 and other cell-adherens junction molecules (Rho GTPase-activating protein [RhoGAP] and E-cadherin) in metastatic diffuse-type gastric cancer (mDGC).
Tue Dec 01 00:00:00 EST 2020
Core Binding Factors are essential for ovulation, luteinization, and female fertility in mice.
Scientific reports
Lee-Thacker S,Jeon H,Choi Y,Taniuchi I,Takarada T,Yoneda Y,Ko C,Jo M
700178 was used in Immunohistochemistry to provide in vivo evidence that CBFs act as essential transcriptional regulators of both ovulation and luteinization by regulating the expression of key genes that are involved in inflammation, matrix remodeling, cell differentiation, vascularization, and steroid metabolisms in mice.
Thu Jun 18 00:00:00 EDT 2020
Core Binding Factors are essential for ovulation, luteinization, and female fertility in mice.
Scientific reports
Lee-Thacker S,Jeon H,Choi Y,Taniuchi I,Takarada T,Yoneda Y,Ko C,Jo M
700178 was used in Immunohistochemistry to provide in vivo evidence that CBFs act as essential transcriptional regulators of both ovulation and luteinization by regulating the expression of key genes that are involved in inflammation, matrix remodeling, cell differentiation, vascularization, and steroid metabolisms in mice.
Thu Jun 18 00:00:00 EDT 2020
Nuclear staining of claudin-18 is a new immunohistochemical marker for diagnosing intramucosal well-differentiated gastric adenocarcinoma.
Pathology international
Takahashi Y,Tsutsumi Y,Takeuchi C,Shiogama K,Mizutani Y,Inada KI,Yamamichi N,Koike K
700178 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to evaluate the association between histopathology and immunohistochemical expression of MUC1, HER2, p53, CEA, E-cadherin, β-catenin and claudin-18.
Tue Sep 01 00:00:00 EDT 2020
Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism.
Developmental cell
Krah NM,Narayanan SM,Yugawa DE,Straley JA,Wright CVE,MacDonald RJ,Murtaugh LC
700178 was used in Immunohistochemistry to suggest that reactivation of an endogenous differentiation program can prevent and reverse oncogene-driven transformation in cells harboring tumor-driving mutations, introducing a potential paradigm for solid tumor prevention and treatment.
Mon Sep 23 00:00:00 EDT 2019
Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis.
Cellular and molecular gastroenterology and hepatology
Quilichini E,Fabre M,Dirami T,Stedman A,De Vas M,Ozguc O,Pasek RC,Cereghini S,Morillon L,Guerra C,Couvelard A,Gannon M,Haumaitre C
700178 was used in Immunohistochemistry to reveal that Hnf1b deficiency may contribute to diseases of the exocrine pancreas and could gain further insight into the etiology of pancreatitis and tumorigenesis.
Mon Jul 20 00:00:00 EDT 2020
Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes.
PloS one
Weber B,Mendler MR,Lackner I,von Zelewski A,Höfler S,Baur M,Braun CK,Hummler H,Schwarz S,Pressmar J,Kalbitz M
700178 was used in Immunocytochemistry-immunoflourescence to study early morphological, immunological and structural alterations in lung tissue after asphyxia and hemorrhage.
Fri Feb 21 00:00:00 EST 2020
Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.
The Journal of clinical investigation
Zhou B,Flodby P,Luo J,Castillo DR,Liu Y,Yu FX,McConnell A,Varghese B,Li G,Chimge NO,Sunohara M,Koss MN,Elatre W,Conti P,Liebler JM,Yang C,Marconett CN,Laird-Offringa IA,Minoo P,Guan K,Stripp BR,Crandall ED,Borok Z
700178 was used in Immunocytochemistry to establish CLDN18 as a regulator of YAP activity that serves to restrict organ size, progenitor cell proliferation, and tumorigenesis in the murine lung.
Thu Mar 01 00:00:00 EST 2018
Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.
The Journal of clinical investigation
Zhou B,Flodby P,Luo J,Castillo DR,Liu Y,Yu FX,McConnell A,Varghese B,Li G,Chimge NO,Sunohara M,Koss MN,Elatre W,Conti P,Liebler JM,Yang C,Marconett CN,Laird-Offringa IA,Minoo P,Guan K,Stripp BR,Crandall ED,Borok Z
700178 was used in Immunocytochemistry to establish CLDN18 as a regulator of YAP activity that serves to restrict organ size, progenitor cell proliferation, and tumorigenesis in the murine lung.
Thu Mar 01 00:00:00 EST 2018
Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.
The Journal of clinical investigation
Zhou B,Flodby P,Luo J,Castillo DR,Liu Y,Yu FX,McConnell A,Varghese B,Li G,Chimge NO,Sunohara M,Koss MN,Elatre W,Conti P,Liebler JM,Yang C,Marconett CN,Laird-Offringa IA,Minoo P,Guan K,Stripp BR,Crandall ED,Borok Z
700178 was used in Immunocytochemistry to establish CLDN18 as a regulator of YAP activity that serves to restrict organ size, progenitor cell proliferation, and tumorigenesis in the murine lung.
Thu Mar 01 00:00:00 EST 2018
CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro.
International journal of cancer
Luo J,Chimge NO,Zhou B,Flodby P,Castaldi A,Firth AL,Liu Y,Wang H,Yang C,Marconett CN,Crandall ED,Offringa IA,Frenkel B,Borok Z
Published figure using Claudin 18 recombinant monoclonal antibody (Product # 700178) in Western Blot
Sat Dec 15 00:00:00 EST 2018
Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs.
Tissue barriers
Chen H,Lu R,Zhang YG,Sun J
700178 was used in Western Blotting to study the role of the vitamin D receptor in lung barrier integrity.
Mon Apr 01 00:00:00 EDT 2019
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
eLife
Krah NM,De La O JP,Swift GH,Hoang CQ,Willet SG,Chen Pan F,Cash GM,Bronner MP,Wright CV,MacDonald RJ,Murtaugh LC
Published figure using Claudin 18 monoclonal antibody (Product # 700178) in Immunohistochemistry
Tue Jul 07 00:00:00 EDT 2015
The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function.
American journal of physiology. Lung cellular and molecular physiology
Overgaard CE,Schlingmann B,Dorsainvil White S,Ward C,Fan X,Swarnakar S,Brown LA,Guidot DM,Koval M
700178 was used in western blot to test if the relative balance of GM-CSF and TGF-β signaling regulates lung epithelial barrier function.
Mon Jun 15 00:00:00 EDT 2015
The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function.
American journal of physiology. Lung cellular and molecular physiology
Overgaard CE,Schlingmann B,Dorsainvil White S,Ward C,Fan X,Swarnakar S,Brown LA,Guidot DM,Koval M
700178 was used in western blot to test if the relative balance of GM-CSF and TGF-β signaling regulates lung epithelial barrier function.
Mon Jun 15 00:00:00 EDT 2015
NF-κB inhibitors impair lung epithelial tight junctions in the absence of inflammation.
Tissue barriers
Ward C,Schlingmann B,Stecenko AA,Guidot DM,Koval M
700178 was used in immunohistochemistry to investigate the effect of NF-kappaB inhibitors on lung epithelial tight junctions in the absence of inflammation
Fri Apr 03 00:00:00 EDT 2015
NF-κB inhibitors impair lung epithelial tight junctions in the absence of inflammation.
Tissue barriers
Ward C,Schlingmann B,Stecenko AA,Guidot DM,Koval M
700178 was used in immunohistochemistry to investigate the effect of NF-kappaB inhibitors on lung epithelial tight junctions in the absence of inflammation
Fri Apr 03 00:00:00 EDT 2015
CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.
Cancer immunology research
Zhang Y,Yan W,Mathew E,Bednar F,Wan S,Collins MA,Evans RA,Welling TH,Vonderheide RH,di Magliano MP
Published figure using Claudin 18 recombinant monoclonal antibody (Product # 700178) in Immunohistochemistry
Thu May 01 00:00:00 EDT 2014
Primary gastric Merkel cell carcinoma harboring DNA polyomavirus: first description of an unusual high-grade neuroendocrine carcinoma.
Human pathology
Capella C,Marando A,Longhi E,Bernasconi B,Finzi G,Parravicini C,Sessa F,La Rosa S
700178 was used in immunohistochemistry to reoprt on a case of an unusual primary gastric Merkel cell carcinoma
Sun Jun 01 00:00:00 EDT 2014
Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
Cancer research
Zhang Y,Yan W,Collins MA,Bednar F,Rakshit S,Zetter BR,Stanger BZ,Chung I,Rhim AD,di Magliano MP
Published figure using Claudin 18 recombinant monoclonal antibody (Product # 700178) in Immunohistochemistry
Tue Oct 15 00:00:00 EDT 2013
Linear and micronodular neuroendocrine cell hyperplasia in an ovarian mucinous cystadenoma.
Pathology, research and practice
Dainese E,Cimetti L,Capella C,Riva C
700178 was used in immunohistochemistry to report on a case of ovarian mucinous cystadenoma
Tue Oct 01 00:00:00 EDT 2013
Distribution of LGR5+ cells and associated implications during the early stage of gastric tumorigenesis.
PloS one
Jang BG,Lee BL,Kim WH
700178 was used in immunohistochemistry to study the potential cancer stem cell role of LGR5+ cells in gastric tumorigenesis
Fri Sep 19 00:00:00 EDT 2014
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice.
The Journal of clinical investigation
Collins MA,Bednar F,Zhang Y,Brisset JC,Galbán S,Galbán CJ,Rakshit S,Flannagan KS,Adsay NV,Pasca di Magliano M
Published figure using Claudin 18 recombinant monoclonal antibody (Product # 700178) in Immunohistochemistry
Wed Feb 01 00:00:00 EST 2012
