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Claudin 7 Antibody (PA5-23689) in IHC (P)
Immunohistochemistry analysis of Claudin 7 in formalin fixed and paraffin embedded human prostate carcinoma. Samples were incubated with Claudin 7 polyclonal antibody (Product # PA5-23689) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-23689
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 172-201 amino acids from the C-terminal region of human CLDN7
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2541189
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Claudin-7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2
Gene Aliases: CEPTRL2; claudin-1; CLDN-7; CLDN7; CPETRL2; Hs.84359
UniProt ID: (Human) O95471
Entrez Gene ID: (Human) 1366
positive regulation of defense response to virus by host
negative regulation of cell adhesion
positive regulation of cell proliferation
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
negative regulation of protein homooligomerization
negative regulation of apoptotic process
xenophagy
positive regulation of cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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